Relationship between vitamin D and magnesium

Semih Kalyon

Makale detayları

Relationship between vitamin D and magnesium

Yazarlar:

Semih Kalyon

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.402-408

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286339

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: Vitamin D is a steroid hormone that plays an essential role in healthy bone structure. Magnesium plays a role as a cofactor for enzymes in vitamin D synthesis and degradation. The study aims to determine whether there is also accompanying magnesium deficiency, in patients with vitamin D deficiency or insufficiency. Materials and Methods: Patients over the age of 18 who applied to the internal medicine outpatient clinic of our tertiary center for any reason between 01.10.2018 and 01.10.2020 were screened and patients whose serum glucose, ALT, creatinine, Vitamin D, and magnesium values were all present at the same time were selected. Pregnant and lactating women, patients with malignancy, chronic renal failure, hyperparathyroidism, or hypoparathyroidism, and patients under vitamin D or magnesium supplementation were excluded. Age, gender, and laboratory data of the included patients were recorded. Results: A total of 5982 patients, 1197 male and 4785 female, were included in this study. The mean age of the cases was 42 years. There was no statistically significant relationship between Vitamin D values and magnesium or glucose levels However, there was a statistically significant relationship between serum vitamin D levels and age and serum creatinine and ALT levels. Both vitamin D and magnesium levels in women were found to be statistically significantly lower than in men. Conclusion: Since there was no relationship between Vitamin D and magnesium levels, there is no need for a routine magnesium examination to be performed in patients with vitamin D deficiency or insufficiency who are planned to take vitamin D therapy.

 Purpose: Vitamin D is a steroid hormone that plays an essential role in healthy bone structure. Magnesium plays a role as a cofactor for enzymes in vitamin D synthesis and degradation. The study aims to determine whether there is also accompanying magnesium deficiency, in patients with vitamin D deficiency or insufficiency. Materials and Methods: Patients over the age of 18 who applied to the internal medicine outpatient clinic of our tertiary center for any reason between 01.10.2018 and 01.10.2020 were screened and patients whose serum glucose, ALT, creatinine, Vitamin D, and magnesium values were all present at the same time were selected. Pregnant and lactating women, patients with malignancy, chronic renal failure, hyperparathyroidism, or hypoparathyroidism, and patients under vitamin D or magnesium supplementation were excluded. Age, gender, and laboratory data of the included patients were recorded. Results: A total of 5982 patients, 1197 male and 4785 female, were included in this study. The mean age of the cases was 42 years. There was no statistically significant relationship between Vitamin D values and magnesium or glucose levels However, there was a statistically significant relationship between serum vitamin D levels and age and serum creatinine and ALT levels. Both vitamin D and magnesium levels in women were found to be statistically significantly lower than in men. Conclusion: Since there was no relationship between Vitamin D and magnesium levels, there is no need for a routine magnesium examination to be performed in patients with vitamin D deficiency or insufficiency who are planned to take vitamin D therapy.

 Purpose: Vitamin D is a steroid hormone that plays an essential role in healthy bone structure. Magnesium plays a role as a cofactor for enzymes in vitamin D synthesis and degradation. The study aims to determine whether there is also accompanying magnesium deficiency, in patients with vitamin D deficiency or insufficiency. Materials and Methods: Patients over the age of 18 who applied to the internal medicine outpatient clinic of our tertiary center for any reason between 01.10.2018 and 01.10.2020 were screened and patients whose serum glucose, ALT, creatinine, Vitamin D, and magnesium values were all present at the same time were selected. Pregnant and lactating women, patients with malignancy, chronic renal failure, hyperparathyroidism, or hypoparathyroidism, and patients under vitamin D or magnesium supplementation were excluded. Age, gender, and laboratory data of the included patients were recorded. Results: A total of 5982 patients, 1197 male and 4785 female, were included in this study. The mean age of the cases was 42 years. There was no statistically significant relationship between Vitamin D values and magnesium or glucose levels However, there was a statistically significant relationship between serum vitamin D levels and age and serum creatinine and ALT levels. Both vitamin D and magnesium levels in women were found to be statistically significantly lower than in men. Conclusion: Since there was no relationship between Vitamin D and magnesium levels, there is no need for a routine magnesium examination to be performed in patients with vitamin D deficiency or insufficiency who are planned to take vitamin D therapy.

 Amaç: Sağlıklı kemik yapısında önemli rol oynayan D Vitamini steroid yapıda bir hormondur. Magnezyum ise birçok görevinin yanısıra D vitamin sentezi ve yıkımı enzimlerin de kofaktörü olarak rol almaktadır. D vitamin eksikliği veya yetersizliğinde aynı zamanda Magnezyum düşüklüğünün de olup olmadığını anlamak bu çalışmanın amacıdır. Gereç veYöntem: Herhangi bir sebeple 3. basamak hastanemiz dahiliye polikliniğine 01.10.2018-01.10.2020 tarihleri arasında başvuran 18 yaş üzerindeki hastalar taranıp gluko, ALT, kreatinin, D vitamini, magnezyum değerlerinin hepsi aynı anda test edilmiş hastalar seçildi. Gebeler ve emzirenler, malignitesi olanlar, kronik böbrek yetmezliği olanlar, hiperparatiroidisi, hipoparatiroidisiolanlar, D vitamin veya magnezyum desteği alanlar elendi. Geriye kalan hastaların yaş, cinsiyet ve laboratuvar değerleri kaydedildi. Bulgular: Bu çalışmaya 1197si erkekve 4785i kadın 5982 hasta alınmıştır. Olguların yaşları ortalaması 42dir. D vitamin değerleri ile magnezyum ve glukoz değerleri arasında istatistiksel olarak anlamlı bir ilişki bulunmamaktadır. Ancak D vitamin ile yaş, kreatininve ALT arasında istatistiksel olarak anlamlı bir ilişki mevcuttur ayrıca kadınlarda hem D vitamini hem de magnezyum düzeyi erkeklere göre istatistiksel olarak anlamlı düzeyde daha düşük bulunmuştur. Sonuç: D Vitamini ile magnezyum arasında bir ilişki saptanamadığından dolayı D vitamin tedavisi başlanacak olan D vitamin eksik veya yetersiz hastalara rutin magnezyum tetkikinin de yapılmasına gerek yoktur.

Makale detayları

Relationship between vitamin D and magnesium

Yazarlar:

Semih Kalyon

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.402-408

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286339

pISSN:

2602-3032

Vitamin D

magnesium

deiodinase

Vitamin D

Magnezyum

Deiyodinaz

Sayı

Makale detayları

Relationship between vitamin D and magnesium

Yazarlar: Semih Kalyon

Yayıncı: Cukurova University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Cukurova Medical Journal Vol.48 Issue 2, pp.402-408

Belge Tipi: Makale

Yayın Tarihi: 2/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286339

pISSN: 2602-3032

Vitamin D

magnesium

deiodinase

Vitamin D

Magnezyum

Deiyodinaz

Sayı

Yazarlar:

Semih Kalyon

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.402-408

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286339

pISSN:

2602-3032