Evaluation of Clinical and Microbiological Features of Intraabdominal Abscesses in A Tertiary Hospital in Türkiye

Suzan Şahin; Bülent Kaya; Serap Demir Tekol

Makale detayları

Evaluation of Clinical and Microbiological Features of Intraabdominal Abscesses in A Tertiary Hospital in Türkiye

Yazarlar:

Suzan Şahin | Bülent Kaya | Serap Demir Tekol

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Bulaşıcı Hastalıklar

Dergi:

Osmangazi Tıp Dergisi Vol.47 Issue 2, pp.277-284

Belge Tipi:

Makale

Yayın Tarihi:

2/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339261

pISSN:

1305-4953

Anahtar kelimeler:

Özet:

 Knowing the causative agents and microbiological susceptibility in intra-abdominal abscess IAA cases guides empirical antibiotic selection. We aimed to investigate the causative agents, susceptibility, and treatment options in intra-abdominal abscesses. Patients hospitalized with intra-abdominal abscesses between January 2020 and December 2022, in whom abscess material cultures yielded growth, were retrospectively analyzed. Risk factors, causative agents, antibiotic susceptibilities, and treatment options were evaluated. A total of 43 patients, with a mean age of 57.2 years range 22-88, consisting of 30 males 69.8 and 13 females 30.2, were included in the study. Eleven patients had no underlying diseases, while gastrointestinal conditions constituted the majority of underlying diseases n11, 25.6. The most common site of abscess was the liver n19, 44.2, followed by intraperitoneal n14, 32.6, retroperitoneal n5, 11.6 regions. The most frequently used imaging method was computed tomography CT in 29 patients 67.5. A total of 60 microorganisms were isolated from the 43 patients included in the study. The majority of the isolated microorganisms were Gram-negative bacteria n42, 70.0. In 15 patients 34.9 who initially received empirical antibiotic treatment, the treatment was subsequently modified to broad-spectrum antibiotics based on the resistance profile of the isolated microorganism. In patients monitored for intra-abdominal abscesses, initiating appropriate empirical antimicrobial therapy before culture results become available can be crucial. Once the infectious agent is identified and its resistance profile determined, targeted treatment can be administered. Each institutions awareness of its own antibiotic resistance patterns will guide empirical therapies effectively.

 Knowing the causative agents and microbiological susceptibility in intra-abdominal abscess IAA cases guides empirical antibiotic selection. We aimed to investigate the causative agents, susceptibility, and treatment options in intra-abdominal abscesses. Patients hospitalized with intra-abdominal abscesses between January 2020 and December 2022, in whom abscess material cultures yielded growth, were retrospectively analyzed. Risk factors, causative agents, antibiotic susceptibilities, and treatment options were evaluated. A total of 43 patients, with a mean age of 57.2 years range 22-88, consisting of 30 males 69.8 and 13 females 30.2, were included in the study. Eleven patients had no underlying diseases, while gastrointestinal conditions constituted the majority of underlying diseases n11, 25.6. The most common site of abscess was the liver n19, 44.2, followed by intraperitoneal n14, 32.6, retroperitoneal n5, 11.6 regions. The most frequently used imaging method was computed tomography CT in 29 patients 67.5. A total of 60 microorganisms were isolated from the 43 patients included in the study. The majority of the isolated microorganisms were Gram-negative bacteria n42, 70.0. In 15 patients 34.9 who initially received empirical antibiotic treatment, the treatment was subsequently modified to broad-spectrum antibiotics based on the resistance profile of the isolated microorganism. In patients monitored for intra-abdominal abscesses, initiating appropriate empirical antimicrobial therapy before culture results become available can be crucial. Once the infectious agent is identified and its resistance profile determined, targeted treatment can be administered. Each institutions awareness of its own antibiotic resistance patterns will guide empirical therapies effectively.

 Knowing the causative agents and microbiological susceptibility in intra-abdominal abscess IAA cases guides empirical antibiotic selection. We aimed to investigate the causative agents, susceptibility, and treatment options in intra-abdominal abscesses. Patients hospitalized with intra-abdominal abscesses between January 2020 and December 2022, in whom abscess material cultures yielded growth, were retrospectively analyzed. Risk factors, causative agents, antibiotic susceptibilities, and treatment options were evaluated. A total of 43 patients, with a mean age of 57.2 years range 22-88, consisting of 30 males 69.8 and 13 females 30.2, were included in the study. Eleven patients had no underlying diseases, while gastrointestinal conditions constituted the majority of underlying diseases n11, 25.6. The most common site of abscess was the liver n19, 44.2, followed by intraperitoneal n14, 32.6, retroperitoneal n5, 11.6 regions. The most frequently used imaging method was computed tomography CT in 29 patients 67.5. A total of 60 microorganisms were isolated from the 43 patients included in the study. The majority of the isolated microorganisms were Gram-negative bacteria n42, 70.0. In 15 patients 34.9 who initially received empirical antibiotic treatment, the treatment was subsequently modified to broad-spectrum antibiotics based on the resistance profile of the isolated microorganism. In patients monitored for intra-abdominal abscesses, initiating appropriate empirical antimicrobial therapy before culture results become available can be crucial. Once the infectious agent is identified and its resistance profile determined, targeted treatment can be administered. Each institutions awareness of its own antibiotic resistance patterns will guide empirical therapies effectively.

 İntraabdominal apselerde İAA etken mikroorganizmaları ve mikrobiyolojik duyarlılığı bilmek, ampirik antibiyotik seçimine rehberlik eder. İAA de etkenler, antibiyotik duyarlılığı ve tedavi seçeneklerini araştırmayı amaçladık. Ocak 2020 ile Aralık 2022 arasında intraabdominal apse nedeniyle hastaneye yatırılan ve apse materyali kültürlerinde üreme görülen hastalar risk faktörleri, etken ajanlar, antibiyotik duyarlılıkları ve tedavi seçenekleri açısından retrospektif olarak değerlendirildi. Çalışmaya ortalama yaşı 57,2 yıl aralığı 22-88 olan 30 erkek 69,8 ve 13 kadın 30,2 olmak üzere toplam 43 hasta dahil edildi. On bir hastanın altta yatan hastalığı yoktu, altta yatan hastalıkların çoğunluğunu gastrointestinal durumlar oluşturuyordu n11, 25,6. En sık görülen apse bölgesi karaciğerdi n19, 44,2, bunu intraperitoneal n14, 32,6, retroperitoneal n5, 11,6 bölgeler izledi. En sık kullanılan görüntüleme yöntemi 29 hastada 67,5 bilgisayarlı tomografi BT idi. Çalışmaya dahil edilen 43 hastadan toplam 60 mikroorganizma izole edildi. İzole edilen mikroorganizmaların çoğunluğu Gram negatif bakterilerdi n42, 70,0. Başlangıçta ampirik antibiyotik tedavisi alan 15 hastada 34,9, tedavi daha sonra izole edilen mikroorganizmanın direnç profiline göre geniş spektrumlu antibiyotiklere değiştirildi. İntraabdominal apse nedeniyle takip edilen hastalarda kültür sonuçları çıkıncaya kadar uygun ampirik antimikrobiyal tedavi başlanması hayati öneme sahip olabilmektedir. Enfeksiyon etkeni saptandıktan ve direnç durumu belirlendikten sonra etkene yönelik tedavi yapılabilmektedir. Her kurumun kendi antibiyotik direnç durumunu bilmesi ampirik tedavilerde yol gösterici olacaktır.

Makale detayları

Evaluation of Clinical and Microbiological Features of Intraabdominal Abscesses in A Tertiary Hospital in Türkiye

Yazarlar:

Suzan Şahin | Bülent Kaya | Serap Demir Tekol

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Bulaşıcı Hastalıklar

Dergi:

Osmangazi Tıp Dergisi Vol.47 Issue 2, pp.277-284

Belge Tipi:

Makale

Yayın Tarihi:

2/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339261

pISSN:

1305-4953

intra-abdominal abscesses

treatment

rezistanceintra-abdominal apse

tedavi

direnç

Sayı

Makale detayları

Evaluation of Clinical and Microbiological Features of Intraabdominal Abscesses in A Tertiary Hospital in Türkiye

Yazarlar: Suzan Şahin | Bülent Kaya | Serap Demir Tekol

Yayıncı: Eskişehir Osmangazi University

Ana Başlıklar: Bulaşıcı Hastalıklar

Dergi: Osmangazi Tıp Dergisi Vol.47 Issue 2, pp.277-284

Belge Tipi: Makale

Yayın Tarihi: 2/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001339261

pISSN: 1305-4953

intra-abdominal abscesses

treatment

rezistanceintra-abdominal apse

tedavi

direnç

Sayı

Yazarlar:

Suzan Şahin | Bülent Kaya | Serap Demir Tekol

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Bulaşıcı Hastalıklar

Dergi:

Osmangazi Tıp Dergisi Vol.47 Issue 2, pp.277-284

Belge Tipi:

Makale

Yayın Tarihi:

2/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339261

pISSN:

1305-4953