Neutrophil-Lymphocyte Ratio in Septic Arthritis Diagnosis and Treatment Follow-Up

Rıfat Şahin

Makale detayları

Neutrophil-Lymphocyte Ratio in Septic Arthritis Diagnosis and Treatment Follow-Up

Yazarlar:

Rıfat Şahin

Yayıncı:

Kafkas University

Ana Başlıklar:

Ortopedi

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 1, pp.25-30

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001317115

pISSN:

2146-2631

Anahtar kelimeler:

Özet:

 Aim: This study aimed to determine the availability of neutrophilto- lymphocyte ratio NLR in diagnosis and treatment follow-up by determining the changing values when septic arthritis SA is diagnosed and during treatment. Material and Method: This retrospective study is based on examining the laboratory results of 44 adult patients with a diagnosis of SA. Laboratory values, white blood cell count WBC, C-reactive protein CRP, and NLR of the patients on days 0, 5, 10, and 14 and the results of the joint fluid analysis were evaluated. Results: The mean number of cells in the joint fluid of the patients was 46 thousand, and the mean PMNL rate was 89.4. Microorganisms were seen in gram staining of joint puncture fluid of only four patients 9.1. The number of patients with growth in joint fluid culture was only 11 25. The mean values for days 0, 5, 10, and 14 were, respectively, 135.2, 88.1, 47.3, and 22.2 for CRP; 9.94, 7.86, 7.42, and 7.44 for WBC; 4.9, 3.8, 3.0 and 2.4 for NLR. Conclusion: NLR may serve as a valuable biomarker for diagnosing and monitoring treatment in SA, particularly given the low prevalence of microorganisms in gram stains and joint fluid cultures and the variability in cell counts in joint fluid samples. In patients diagnosed with SA, the mean NLR value is 4.9 and consistently decreases during treatment. Within two weeks of initiating treatment, NLR typically decreases by approximately half. This biomarker can aid in diagnosing and ongoing managing SA, offering a cost-effective and readily available indicator that should be routinely considered.

 Aim: This study aimed to determine the availability of neutrophilto- lymphocyte ratio NLR in diagnosis and treatment follow-up by determining the changing values when septic arthritis SA is diagnosed and during treatment. Material and Method: This retrospective study is based on examining the laboratory results of 44 adult patients with a diagnosis of SA. Laboratory values, white blood cell count WBC, C-reactive protein CRP, and NLR of the patients on days 0, 5, 10, and 14 and the results of the joint fluid analysis were evaluated. Results: The mean number of cells in the joint fluid of the patients was 46 thousand, and the mean PMNL rate was 89.4. Microorganisms were seen in gram staining of joint puncture fluid of only four patients 9.1. The number of patients with growth in joint fluid culture was only 11 25. The mean values for days 0, 5, 10, and 14 were, respectively, 135.2, 88.1, 47.3, and 22.2 for CRP; 9.94, 7.86, 7.42, and 7.44 for WBC; 4.9, 3.8, 3.0 and 2.4 for NLR. Conclusion: NLR may serve as a valuable biomarker for diagnosing and monitoring treatment in SA, particularly given the low prevalence of microorganisms in gram stains and joint fluid cultures and the variability in cell counts in joint fluid samples. In patients diagnosed with SA, the mean NLR value is 4.9 and consistently decreases during treatment. Within two weeks of initiating treatment, NLR typically decreases by approximately half. This biomarker can aid in diagnosing and ongoing managing SA, offering a cost-effective and readily available indicator that should be routinely considered.

 Aim: This study aimed to determine the availability of neutrophilto- lymphocyte ratio NLR in diagnosis and treatment follow-up by determining the changing values when septic arthritis SA is diagnosed and during treatment. Material and Method: This retrospective study is based on examining the laboratory results of 44 adult patients with a diagnosis of SA. Laboratory values, white blood cell count WBC, C-reactive protein CRP, and NLR of the patients on days 0, 5, 10, and 14 and the results of the joint fluid analysis were evaluated. Results: The mean number of cells in the joint fluid of the patients was 46 thousand, and the mean PMNL rate was 89.4. Microorganisms were seen in gram staining of joint puncture fluid of only four patients 9.1. The number of patients with growth in joint fluid culture was only 11 25. The mean values for days 0, 5, 10, and 14 were, respectively, 135.2, 88.1, 47.3, and 22.2 for CRP; 9.94, 7.86, 7.42, and 7.44 for WBC; 4.9, 3.8, 3.0 and 2.4 for NLR. Conclusion: NLR may serve as a valuable biomarker for diagnosing and monitoring treatment in SA, particularly given the low prevalence of microorganisms in gram stains and joint fluid cultures and the variability in cell counts in joint fluid samples. In patients diagnosed with SA, the mean NLR value is 4.9 and consistently decreases during treatment. Within two weeks of initiating treatment, NLR typically decreases by approximately half. This biomarker can aid in diagnosing and ongoing managing SA, offering a cost-effective and readily available indicator that should be routinely considered.

 Aim: This study aimed to determine the availability of neutrophilto- lymphocyte ratio NLR in diagnosis and treatment follow-up by determining the changing values when septic arthritis SA is diagnosed and during treatment. Material and Method: This retrospective study is based on examining the laboratory results of 44 adult patients with a diagnosis of SA. Laboratory values, white blood cell count WBC, C-reactive protein CRP, and NLR of the patients on days 0, 5, 10, and 14 and the results of the joint fluid analysis were evaluated. Results: The mean number of cells in the joint fluid of the patients was 46 thousand, and the mean PMNL rate was 89.4. Microorganisms were seen in gram staining of joint puncture fluid of only four patients 9.1. The number of patients with growth in joint fluid culture was only 11 25. The mean values for days 0, 5, 10, and 14 were, respectively, 135.2, 88.1, 47.3, and 22.2 for CRP; 9.94, 7.86, 7.42, and 7.44 for WBC; 4.9, 3.8, 3.0 and 2.4 for NLR. Conclusion: NLR may serve as a valuable biomarker for diagnosing and monitoring treatment in SA, particularly given the low prevalence of microorganisms in gram stains and joint fluid cultures and the variability in cell counts in joint fluid samples. In patients diagnosed with SA, the mean NLR value is 4.9 and consistently decreases during treatment. Within two weeks of initiating treatment, NLR typically decreases by approximately half. This biomarker can aid in diagnosing and ongoing managing SA, offering a cost-effective and readily available indicator that should be routinely considered.

Makale detayları

Neutrophil-Lymphocyte Ratio in Septic Arthritis Diagnosis and Treatment Follow-Up

Yazarlar:

Rıfat Şahin

Yayıncı:

Kafkas University

Ana Başlıklar:

Ortopedi

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 1, pp.25-30

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001317115

pISSN:

2146-2631

arthritis

septic

neutrophils

lymphocytes; biomarkers

Sayı

Makale detayları

Neutrophil-Lymphocyte Ratio in Septic Arthritis Diagnosis and Treatment Follow-Up

Yazarlar: Rıfat Şahin

Yayıncı: Kafkas University

Ana Başlıklar: Ortopedi

Dergi: Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 1, pp.25-30

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001317115

pISSN: 2146-2631

arthritis

septic

neutrophils

lymphocytes; biomarkers

Sayı

Yazarlar:

Rıfat Şahin

Yayıncı:

Kafkas University

Ana Başlıklar:

Ortopedi

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.14 Issue 1, pp.25-30

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001317115

pISSN:

2146-2631