Clinical Significance of Liver and Spleen Stiffness: Evaluation with Shear Wave Ultrasound Elastography

N.A.

Makale detayları

Clinical Significance of Liver and Spleen Stiffness: Evaluation with Shear Wave Ultrasound Elastography

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Radiology and Organ Imaging

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.77 Issue 1, pp.34-38

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001349786

pISSN:

0365-8104

Anahtar kelimeler:

Özet:

 Objectives: To investigate clinical significance of liver and spleen stiffness in patients with chronic parenchymal liver disease. Materials and Methods: Fifty patients with chronic parenchymal liver disease who underwent 2D ultrasound US shear wave elastography SWE in the Ultrasonography Unit of Ankara University Medical Faculty Hospital between November 2018-June 2021 were enrolled in our prospective study. Liver size, contour, echogenicity, presence of portosystemic collateralls, and ascites were investigated on B-mode examination. Portal vein diameter was measured. Splenic volume was calculated. Liver and spleen stiffness values were measured by 2D SWE. Serum platelet count was noted. Child- Pugh score was calculated for all patients. Results: Thirty-four patients were grouped as Child-Pugh A, 15 patients were grouped as Child-Pugh B, 1 patient was grouped as Child-Pugh C. Platelet count was between 51-360x109L. The most common conventional US finding was parenchymal heterogeneity. All patients had splenomegaly, the mean portal vein diameter was 12.58 mm, 34 patients had hepatopedal flow. Portosystemic collateralls were detected in 15 patients. Liver and spleen stiffness values were between 4.12 kPa-16.29 kPa, and 9.20 kPa-29.19 kPa, respectively. There was a positive correlation between liver and spleen stiffness p0.002. The relationship between splenic volume and spleenliver stiffness was statistically significant p0.0004, p0.008, respectively. Both liver and spleen stiffness was correlated with Child-Pugh score p0.02, p0.00003, respectively. There was no statistically significant correlation between portal vein diameter and liverspleen stiffness, and between platelet count and liver stiffness p0.05. The correlation between platelet count and spleen stiffness was statistically significant p0.002. Conclusion: SWE can provide information about the clinical status of the patients. Measuring spleen stiffness is as important as measuring liver stiffness.

 Objectives: To investigate clinical significance of liver and spleen stiffness in patients with chronic parenchymal liver disease. Materials and Methods: Fifty patients with chronic parenchymal liver disease who underwent 2D ultrasound US shear wave elastography SWE in the Ultrasonography Unit of Ankara University Medical Faculty Hospital between November 2018-June 2021 were enrolled in our prospective study. Liver size, contour, echogenicity, presence of portosystemic collateralls, and ascites were investigated on B-mode examination. Portal vein diameter was measured. Splenic volume was calculated. Liver and spleen stiffness values were measured by 2D SWE. Serum platelet count was noted. Child- Pugh score was calculated for all patients. Results: Thirty-four patients were grouped as Child-Pugh A, 15 patients were grouped as Child-Pugh B, 1 patient was grouped as Child-Pugh C. Platelet count was between 51-360x109L. The most common conventional US finding was parenchymal heterogeneity. All patients had splenomegaly, the mean portal vein diameter was 12.58 mm, 34 patients had hepatopedal flow. Portosystemic collateralls were detected in 15 patients. Liver and spleen stiffness values were between 4.12 kPa-16.29 kPa, and 9.20 kPa-29.19 kPa, respectively. There was a positive correlation between liver and spleen stiffness p0.002. The relationship between splenic volume and spleenliver stiffness was statistically significant p0.0004, p0.008, respectively. Both liver and spleen stiffness was correlated with Child-Pugh score p0.02, p0.00003, respectively. There was no statistically significant correlation between portal vein diameter and liverspleen stiffness, and between platelet count and liver stiffness p0.05. The correlation between platelet count and spleen stiffness was statistically significant p0.002. Conclusion: SWE can provide information about the clinical status of the patients. Measuring spleen stiffness is as important as measuring liver stiffness.

 Objectives: To investigate clinical significance of liver and spleen stiffness in patients with chronic parenchymal liver disease. Materials and Methods: Fifty patients with chronic parenchymal liver disease who underwent 2D ultrasound US shear wave elastography SWE in the Ultrasonography Unit of Ankara University Medical Faculty Hospital between November 2018-June 2021 were enrolled in our prospective study. Liver size, contour, echogenicity, presence of portosystemic collateralls, and ascites were investigated on B-mode examination. Portal vein diameter was measured. Splenic volume was calculated. Liver and spleen stiffness values were measured by 2D SWE. Serum platelet count was noted. Child- Pugh score was calculated for all patients. Results: Thirty-four patients were grouped as Child-Pugh A, 15 patients were grouped as Child-Pugh B, 1 patient was grouped as Child-Pugh C. Platelet count was between 51-360x109L. The most common conventional US finding was parenchymal heterogeneity. All patients had splenomegaly, the mean portal vein diameter was 12.58 mm, 34 patients had hepatopedal flow. Portosystemic collateralls were detected in 15 patients. Liver and spleen stiffness values were between 4.12 kPa-16.29 kPa, and 9.20 kPa-29.19 kPa, respectively. There was a positive correlation between liver and spleen stiffness p0.002. The relationship between splenic volume and spleenliver stiffness was statistically significant p0.0004, p0.008, respectively. Both liver and spleen stiffness was correlated with Child-Pugh score p0.02, p0.00003, respectively. There was no statistically significant correlation between portal vein diameter and liverspleen stiffness, and between platelet count and liver stiffness p0.05. The correlation between platelet count and spleen stiffness was statistically significant p0.002. Conclusion: SWE can provide information about the clinical status of the patients. Measuring spleen stiffness is as important as measuring liver stiffness.

 Amaç: Kronik karaciğer parankim hastalığı olanlarda karaciğer ve dalak sertliğinin klinik önemini araştırmaktır. Gereç ve Yöntem: Prospektif çalışmamıza, Kasım 2018-Haziran 2021 tarihleri arasında Ankara Üniversitesi Tıp Fakültesi Hastanesi Ultrasonografi Ünitesinde ultrason US shear wave elastografi SWE ve abdomen US incelemesi yapılan kronik karaciğer parankim hastalığı olan elli hasta dahil edildi. B-mod incelemede karaciğer boyutu, konturu, ekojenitesi, portosistemik kollaterallerin varlığı ve asit araştırıldı. Portal ven çapı ölçüldü. Dalak hacmi hesaplandı. Karaciğer ve dalak sertlik değerleri SWE ile ölçüldü. Serum trombosit sayısı not edildi. Tüm hastalar için Child-Pugh skoru hesaplandı. Bulgular: Otuz dört hasta Child-Pugh A, 15 hasta Child-Pugh B, 1 hasta Child-Pugh C grubundaydı. Trombosit sayısı 51-360 x109L arasındaydı. En yaygın konvansiyonel US bulgusu parankimal heterojeniteydi. Tüm hastalarda splenomegali vardı, ortalama portal ven çapı 12,58 mm idi, 34 hastada hepatopedal akım vardı. On beş hastada portosistemik kollateraller saptandı. Karaciğer ve dalak sertlik değerleri sırasıyla 4.12 kPa-16.29 kPa ve 9.20kPa-29.19 kPa arasındaydı. Karaciğer ve dalak sertliği arasında pozitif korelasyon vardı p0,002. Dalak hacmi ile dalakkaraciğer sertliği arasındaki ilişki istatistiksel olarak anlamlıydı sırasıyla p0,0004, p0,008. Hem karaciğer hem de dalak sertliği Child-Pugh skoru ile koreleydi sırasıyla p0,02, p0,00003. Portal ven çapı ile karaciğerdalak sertliği arasında ve trombosit sayısı ile karaciğer sertliği arasında istatistiksel olarak anlamlı bir ilişki yoktu p0,05. Trombosit sayısı ile dalak sertliği arasındaki korelasyon istatistiksel olarak anlamlıydı p0,002. Sonuç: SWE, hastaların klinik durumu hakkında bilgi sağlayabilir. Dalak sertliğini ölçmek, karaciğer sertliğini ölçmek kadar önemlidir.

Makale detayları

Clinical Significance of Liver and Spleen Stiffness: Evaluation with Shear Wave Ultrasound Elastography

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Radiology and Organ Imaging

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.77 Issue 1, pp.34-38

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001349786

pISSN:

0365-8104

Cirrhosis

portal hypertension

elastography

ultrasoundSiroz

portal hipertansiyon

elastografi

ultrason

Sayı

Makale detayları

Yazarlar: N.A.

Yayıncı: Ankara University

Ana Başlıklar: Radiology and Organ Imaging

Dergi: Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.77 Issue 1, pp.34-38

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001349786

pISSN: 0365-8104

Sayı

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Radiology and Organ Imaging

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.77 Issue 1, pp.34-38

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001349786

pISSN:

0365-8104