Evaluation of segmental distribution of liver metastases in colorectal carcinomas by computed tomography

Neşe Kutlutürk Şahin

Makale detayları

Evaluation of segmental distribution of liver metastases in colorectal carcinomas by computed tomography

Yazarlar:

Neşe Kutlutürk Şahin

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 1, pp.78-83

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001309834

pISSN:

2687-2781

Anahtar kelimeler:

Özet:

 Objective: We aimed to investigate the relationship between the localization of colorectal carcinomas and the topographic distribution of metastatic liver lesions. Material and Methods: Patients diagnosed with colorectal cancer and metastatic liver lesions constituted the target population of this study. Demographic data, primary tumor localization, and data regarding liver metastases were retrieved and retrospectively reviewed. Patient files, including endoscopy and computerized tomography reports, were the primary data source. In addition, data concerning segmental localization of the metastatic liver lesions based on the Couinaud classification were collected. Results: Ninety-six patients were diagnosed with colorectal cancer with liver metastases during the study period. A total of 251 metastases were detected. The number of metastases was 169 67.3 in the right and 80 31.9 in the left lobe p0.0001. Evaluation regarding Couinaud classification elucidated that the most frequently affected segment was segment VIII 23.1, while segment 1 i.e., caudate lobe was the least commonly affected segment. The liver segments with the highest number of metastatic lesions were VIII, V, VII, VI, III, II, IV, and I, respectively. There was no significant difference in the segmental distribution of metastases in patients with primary tumors in the right and left colon p0.05. Conclusion: Liver metastases of colorectal cancer are significantly more common in the right lobe than the left lobe, irrespective of the location of the colorectal tumor. Segment VIII of the right lobe is the main target of the metastases.

 Objective: We aimed to investigate the relationship between the localization of colorectal carcinomas and the topographic distribution of metastatic liver lesions. Material and Methods: Patients diagnosed with colorectal cancer and metastatic liver lesions constituted the target population of this study. Demographic data, primary tumor localization, and data regarding liver metastases were retrieved and retrospectively reviewed. Patient files, including endoscopy and computerized tomography reports, were the primary data source. In addition, data concerning segmental localization of the metastatic liver lesions based on the Couinaud classification were collected. Results: Ninety-six patients were diagnosed with colorectal cancer with liver metastases during the study period. A total of 251 metastases were detected. The number of metastases was 169 67.3 in the right and 80 31.9 in the left lobe p0.0001. Evaluation regarding Couinaud classification elucidated that the most frequently affected segment was segment VIII 23.1, while segment 1 i.e., caudate lobe was the least commonly affected segment. The liver segments with the highest number of metastatic lesions were VIII, V, VII, VI, III, II, IV, and I, respectively. There was no significant difference in the segmental distribution of metastases in patients with primary tumors in the right and left colon p0.05. Conclusion: Liver metastases of colorectal cancer are significantly more common in the right lobe than the left lobe, irrespective of the location of the colorectal tumor. Segment VIII of the right lobe is the main target of the metastases.

 Objective: We aimed to investigate the relationship between the localization of colorectal carcinomas and the topographic distribution of metastatic liver lesions. Material and Methods: Patients diagnosed with colorectal cancer and metastatic liver lesions constituted the target population of this study. Demographic data, primary tumor localization, and data regarding liver metastases were retrieved and retrospectively reviewed. Patient files, including endoscopy and computerized tomography reports, were the primary data source. In addition, data concerning segmental localization of the metastatic liver lesions based on the Couinaud classification were collected. Results: Ninety-six patients were diagnosed with colorectal cancer with liver metastases during the study period. A total of 251 metastases were detected. The number of metastases was 169 67.3 in the right and 80 31.9 in the left lobe p0.0001. Evaluation regarding Couinaud classification elucidated that the most frequently affected segment was segment VIII 23.1, while segment 1 i.e., caudate lobe was the least commonly affected segment. The liver segments with the highest number of metastatic lesions were VIII, V, VII, VI, III, II, IV, and I, respectively. There was no significant difference in the segmental distribution of metastases in patients with primary tumors in the right and left colon p0.05. Conclusion: Liver metastases of colorectal cancer are significantly more common in the right lobe than the left lobe, irrespective of the location of the colorectal tumor. Segment VIII of the right lobe is the main target of the metastases.

 Giriş: Bu çalışmada kolorektal karsinomlar ile metastatik karaciğer lezyonlarının topografik dağılımı arasındaki ilişki araştırılmıştır. Gereç ve Yöntemler: Kolorektal kanseri ve metastatik karaciğer lezyonları olan hastalar bu çalışmanın hedef popülasyonunu oluşturdu. Demografik veriler, primer tümör lokalizasyonu, ve metastatik karaciğer lezyonlarının segmental dağılımına ilişkin veriler retrospektif olarak tarandı. Hasta dosyaları, endoskopi ve bilgisayarlı tomografi raporları gözden geçirildi. Ek olarak hastaların Couinaud klasifikasyonuna göre belirlenmiş olan metastatik karaciğer lezyonlarının segmental dağılım bilgileri tarandı. Bulgular: Doksan altı hastanın karaciğer metastazı yapmış kolorektal kanseri tanısı almış olduğu öğrenildi. Toplamda 251 metastatik karaciğer lezyonu saptandı. Bunların 169 67.3 tanesi sağ lobda, 80 31.9 tanesi ise sol lobda yer almaktaydı p0.0001. Couinaud klasifikasyonuna göre yapılmış olan değerlendirmede en sık etkilenmiş olanın segment VIII 23.1, en nadir etkilenmiş olanın ise segment 1 kaudat lob öldüğü anlaşıldı. En sık tutulan karaciğer segmentleri sırasıyla segment VIII, V, VII, VI, III, II, IV, ve segment Idi. Primer tümörü sağ ve sol kolonda olan hastalar kıyaslandığında metastatik lezyonların segmental dağılımı açısından belirgin fark saptanmadı p0.05. Sonuç: Kolorektal kanserlerin karaciğer metastazları kolorektal tümörün lokalizasyonundan bağımsız olarak daha sağ lobda sol lobdan daha sıktır. Segment 8 en sık tutulan segmenttir.

Makale detayları

Evaluation of segmental distribution of liver metastases in colorectal carcinomas by computed tomography

Yazarlar:

Neşe Kutlutürk Şahin

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 1, pp.78-83

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001309834

pISSN:

2687-2781

colorectal carcinoma

liver metastasis

segmental distribution

Couinaud classificationkolorektal karsinom

karaciğer metastazı

segmental dağılım

Couinaud klasifikasyonu

Sayı

Makale detayları

Yazarlar: Neşe Kutlutürk Şahin

Yayıncı: Akdeniz University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Akdeniz Tıp Dergisi Vol.10 Issue 1, pp.78-83

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001309834

pISSN: 2687-2781

Sayı

Yazarlar:

Neşe Kutlutürk Şahin

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 1, pp.78-83

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001309834

pISSN:

2687-2781