Investigation of the Relationship Between Seizure Duration and Demographic, Clinical and Radiologic Characteristics in Focal to Bilateral Tonic-Clonic Seizures

Furkan Sarıdaş; Gizem Mesut; Aylin Bican Demir; İbrahim Bora

Makale detayları

Investigation of the Relationship Between Seizure Duration and Demographic, Clinical and Radiologic Characteristics in Focal to Bilateral Tonic-Clonic Seizures

Yazarlar:

Furkan Sarıdaş | Gizem Mesut | Aylin Bican Demir | İbrahim Bora

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Uludağ Üniversitesi Tıp Fakültesi Dergisi Vol.50 Issue 1, pp.53-60

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317389

pISSN:

1300-414X

Anahtar kelimeler:

Özet:

 Video-electroencephalographic monitoring VEM is the gold standard for objectively assessing the duration of seizures behavioral and electroencephalographic EEG activity. To date, EEG has clinically evaluated seizure durations in different patient groups. This study aims to reveal the relationship between demographic, clinical, and neuroimaging findings and seizure duration in epilepsy patients with focal onset bilateral tonic-clonic seizures FBTCS evaluated with VEM. Medical histories, neuroimaging, and clinical and ictal EEG findings obtained from VEM recordings of 58 randomly selected patients diagnosed with FBTCS in our center were retrospectively analyzed between April 2005 and January 2024. The shortest focal activity was in frontal lobe epilepsy, and the longest generalized activity was in parietooccipital lobe epilepsy. Focal activity duration was shorter in frontal and external capsule localized lesions and longer in mesial temporal localization. Focal activity duration was longer in mesial temporal sclerosis. The duration of generalized activity was longer in encephalomalacia and polymicrogyria and shorter in cortical dysplasia. Focal activity duration was shorter when lesions were accompanied by cortical atrophy. There was no correlation between the type of anti-seizure medication and seizure duration. Seizure duration may vary according to semiologic findings, radiologic features, and epilepsy syndromes. Their differences may inform the clinician about the type of epilepsy syndrome, the probability of status, and semiologic accompanying findings.

 Video-electroencephalographic monitoring VEM is the gold standard for objectively assessing the duration of seizures behavioral and electroencephalographic EEG activity. To date, EEG has clinically evaluated seizure durations in different patient groups. This study aims to reveal the relationship between demographic, clinical, and neuroimaging findings and seizure duration in epilepsy patients with focal onset bilateral tonic-clonic seizures FBTCS evaluated with VEM. Medical histories, neuroimaging, and clinical and ictal EEG findings obtained from VEM recordings of 58 randomly selected patients diagnosed with FBTCS in our center were retrospectively analyzed between April 2005 and January 2024. The shortest focal activity was in frontal lobe epilepsy, and the longest generalized activity was in parietooccipital lobe epilepsy. Focal activity duration was shorter in frontal and external capsule localized lesions and longer in mesial temporal localization. Focal activity duration was longer in mesial temporal sclerosis. The duration of generalized activity was longer in encephalomalacia and polymicrogyria and shorter in cortical dysplasia. Focal activity duration was shorter when lesions were accompanied by cortical atrophy. There was no correlation between the type of anti-seizure medication and seizure duration. Seizure duration may vary according to semiologic findings, radiologic features, and epilepsy syndromes. Their differences may inform the clinician about the type of epilepsy syndrome, the probability of status, and semiologic accompanying findings.

 Video-electroencephalographic monitoring VEM is the gold standard for objectively assessing the duration of seizures behavioral and electroencephalographic EEG activity. To date, EEG has clinically evaluated seizure durations in different patient groups. This study aims to reveal the relationship between demographic, clinical, and neuroimaging findings and seizure duration in epilepsy patients with focal onset bilateral tonic-clonic seizures FBTCS evaluated with VEM. Medical histories, neuroimaging, and clinical and ictal EEG findings obtained from VEM recordings of 58 randomly selected patients diagnosed with FBTCS in our center were retrospectively analyzed between April 2005 and January 2024. The shortest focal activity was in frontal lobe epilepsy, and the longest generalized activity was in parietooccipital lobe epilepsy. Focal activity duration was shorter in frontal and external capsule localized lesions and longer in mesial temporal localization. Focal activity duration was longer in mesial temporal sclerosis. The duration of generalized activity was longer in encephalomalacia and polymicrogyria and shorter in cortical dysplasia. Focal activity duration was shorter when lesions were accompanied by cortical atrophy. There was no correlation between the type of anti-seizure medication and seizure duration. Seizure duration may vary according to semiologic findings, radiologic features, and epilepsy syndromes. Their differences may inform the clinician about the type of epilepsy syndrome, the probability of status, and semiologic accompanying findings.

 Video-elektroensefalografik izleme VEM, nöbetlerin davranışsal ve elektroensefalografik EEG aktivite süresini objektif olarak değerlendirmek için altın standarttır. Bugüne kadar nöbet süreleri farklı hasta gruplarında klinik olarak veya EEG ile değerlendirilmiştir. Bu çalışma, VEM ile değerlendirilen fokal başlangıçlı bilateral tonik-klonik nöbet FBTKN tanısı olan epilepsi hastalarında, demografik, klinik ve nörogörüntüleme bulguları ile nöbet süresi arasındaki ilişkiyi ortaya koymayı amaçlamaktadır. Nisan 2005 ve Ocak 2024 tarihleri arasında merkezimizde FBTKN tanısı alan rastgele seçilmiş 58 hastanın tıbbi öyküleri, nörogörüntülemeler, VEM kayıtlarından elde edilen klinik ve iktal EEG bulguları retrospektif olarak analiz edildi. En kısa fokal aktivite frontal lob epilepsisinde ve en uzun jeneralize aktivite parietooksipital lob epilepsisindeydi. Fokal aktivite süresi frontal ve eksternal kapsül lokalizasyonlu lezyonlarda daha kısa, mezial temporal lokalizasyonda daha uzundu. Fokal aktivite süresi meziyal temporal sklerozda daha uzundu. Jeneralize aktivite süresi ensefalomalazi ve polimikrogiride daha uzun, kortikal displazide ise daha kısaydı. Lezyonlara kortikal atrofi eşlik ettiğinde fokal aktivite süresi daha kısaydı. Anti nöbet ilaç türü ile nöbet süreleri arasında herhangi bir korelasyon yoktu. Nöbet süreleri semiyolojik bulgulara, radyolojik özelliklere ve epilepsi sendromlarına göre değişebilir. Farklılıkları klinisyen için epilepsi sendromu türü, status olasığı, semiyolojik eşlik eden bulgular hakkında bilgi verici olabilir.

Makale detayları

Investigation of the Relationship Between Seizure Duration and Demographic, Clinical and Radiologic Characteristics in Focal to Bilateral Tonic-Clonic Seizures

Yazarlar:

Furkan Sarıdaş | Gizem Mesut | Aylin Bican Demir | İbrahim Bora

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Uludağ Üniversitesi Tıp Fakültesi Dergisi Vol.50 Issue 1, pp.53-60

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317389

pISSN:

1300-414X

Focal to Bilateral Tonic Clonic Seizure

focal activity duration

generalized activity duration

Ictal eegFokal Başlangıçlı Bilateral Tonik Klonik Nöbet

Fokal aktivite süresi

Jeneralize aktivite süresi

İktal EEG

Sayı

Makale detayları

Yazarlar: Furkan Sarıdaş | Gizem Mesut | Aylin Bican Demir | İbrahim Bora

Yayıncı: Bursa Uludağ University

Ana Başlıklar: Nöroloji ve Nöromüsküler Hastalıklar

Dergi: Uludağ Üniversitesi Tıp Fakültesi Dergisi Vol.50 Issue 1, pp.53-60

Belge Tipi: Makale

Yayın Tarihi: 5/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001317389

pISSN: 1300-414X

Sayı

Yazarlar:

Furkan Sarıdaş | Gizem Mesut | Aylin Bican Demir | İbrahim Bora

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Uludağ Üniversitesi Tıp Fakültesi Dergisi Vol.50 Issue 1, pp.53-60

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317389

pISSN:

1300-414X