The impact of hemovigilance studies on transfusion practices: Single centre experience

Samet Yaman; Gökhan Evren; Bilge Zihar; Emine Beköz; Yurdagül Kökcü; Abdulkerim Yıldız

Makale detayları

The impact of hemovigilance studies on transfusion practices: Single centre experience

Yazarlar:

Samet Yaman | Gökhan Evren | Bilge Zihar | Emine Beköz | Yurdagül Kökcü | Abdulkerim Yıldız

Yayıncı:

Hitit University

Ana Başlıklar:

Hematoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 3, pp.349-355

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329542

pISSN:

2687-4717

Anahtar kelimeler:

Özet:

 Objective: Blood product transfusion is one of the most commonly used medical interventions worldwide. However, transfusion-related adverse events TRAEs can cause morbidity and rarely even mortality. For this reason, hemovigilance studies have recently gained importance in terms of safe and effective implementation of transfusion. Material and Method: Transfusion practices issued in the period of 2016-2023 were analyzed retrospectively. All TRAE including adverse reactions AR and adverse events AE were recorded. The impact of hemovigilance practices on the incidence of TRAE was analyzed by comparing the numbers and types of events between years. Results: In the 8-year period between 2016 and 2023, a total of 135,506 blood products belonging to 45,571 patients were used. 172 adverse reactions AR were reported in 170 patients. The overall AR incidence was found to be 126.8 100000. The highest yearly AR rate was reported in 2018 with 168.04 100000. Since hemovigilance measures were tightened, a statistically significant decrease was recorded in ARs from the beginning of 2020 to date p0.001. Conclusion: The result of the current study demonstrated that a reduction in ARs could be achieved with hemovigilance measures. Although some common TRAEs like allergy seem unlikely to prevent due to the underlying pathophysiological mechanisms, we hope that our study showing that some reactions can be reduced by hemovigilance will encourage clinicians and hemovigilance units. Even though hemovigilance studies are being conducted to improve transfusion safety, the most critical concern is reducing exposure to blood components.

 Objective: Blood product transfusion is one of the most commonly used medical interventions worldwide. However, transfusion-related adverse events TRAEs can cause morbidity and rarely even mortality. For this reason, hemovigilance studies have recently gained importance in terms of safe and effective implementation of transfusion. Material and Method: Transfusion practices issued in the period of 2016-2023 were analyzed retrospectively. All TRAE including adverse reactions AR and adverse events AE were recorded. The impact of hemovigilance practices on the incidence of TRAE was analyzed by comparing the numbers and types of events between years. Results: In the 8-year period between 2016 and 2023, a total of 135,506 blood products belonging to 45,571 patients were used. 172 adverse reactions AR were reported in 170 patients. The overall AR incidence was found to be 126.8 100000. The highest yearly AR rate was reported in 2018 with 168.04 100000. Since hemovigilance measures were tightened, a statistically significant decrease was recorded in ARs from the beginning of 2020 to date p0.001. Conclusion: The result of the current study demonstrated that a reduction in ARs could be achieved with hemovigilance measures. Although some common TRAEs like allergy seem unlikely to prevent due to the underlying pathophysiological mechanisms, we hope that our study showing that some reactions can be reduced by hemovigilance will encourage clinicians and hemovigilance units. Even though hemovigilance studies are being conducted to improve transfusion safety, the most critical concern is reducing exposure to blood components.

 Objective: Blood product transfusion is one of the most commonly used medical interventions worldwide. However, transfusion-related adverse events TRAEs can cause morbidity and rarely even mortality. For this reason, hemovigilance studies have recently gained importance in terms of safe and effective implementation of transfusion. Material and Method: Transfusion practices issued in the period of 2016-2023 were analyzed retrospectively. All TRAE including adverse reactions AR and adverse events AE were recorded. The impact of hemovigilance practices on the incidence of TRAE was analyzed by comparing the numbers and types of events between years. Results: In the 8-year period between 2016 and 2023, a total of 135,506 blood products belonging to 45,571 patients were used. 172 adverse reactions AR were reported in 170 patients. The overall AR incidence was found to be 126.8 100000. The highest yearly AR rate was reported in 2018 with 168.04 100000. Since hemovigilance measures were tightened, a statistically significant decrease was recorded in ARs from the beginning of 2020 to date p0.001. Conclusion: The result of the current study demonstrated that a reduction in ARs could be achieved with hemovigilance measures. Although some common TRAEs like allergy seem unlikely to prevent due to the underlying pathophysiological mechanisms, we hope that our study showing that some reactions can be reduced by hemovigilance will encourage clinicians and hemovigilance units. Even though hemovigilance studies are being conducted to improve transfusion safety, the most critical concern is reducing exposure to blood components.

 Amaç: Kan ürünü transfüzyonu dünya çapında en yaygın kullanılan tıbbi müdahalelerden biridir. Ancak transfüzyonla ilişkili advers olaylar TRAEler, hastalarda morbiditeye ve hatta nadiren mortaliteye neden olabilir. Bu nedenle son yıllarda transfüzyonun güvenli ve etkin uygulanması açısından hemovijilans çalışmaları önem kazanmıştır. Gereç ve Yöntem: 2016-2023 döneminde yayımlanan transfüzyon uygulamaları geriye dönük olarak incelendi. Olumsuz reaksiyonlar AR ve olumsuz olaylar AE dahil olmak üzere tüm TRAE kaydedildi. Hemovijilans uygulamalarının TRAE insidansına etkisi, yıllar arasında olay sayısı ve türü karşılaştırılarak analiz edildi. Bulgular: 2016-2023 yılları arasında toplam 8 yıl boyunca toplam 45571 hasta için 135506 kan ürünü kullanıldı. 170 hastada 172 advers reaksiyon AR bildirildi. Genel AR insidansı 126,8 100000 olarak bulundu. Yıllık en yüksek AR oranı 168,04 100000 ile 2018 yılında bildirildi. Hemovijilans tedbirleri sıkılaştırıldığı için ARlerde 2020 yılı başından bugüne istatistiksel olarak anlamlı bir düşüş kaydedildi p0.001. Sonuç: Bu çalışmanın sonucu, hemovijilans önlemleriyle ARlerde azalmanın sağlanabileceğini gösterdi. Alerji gibi yaygın görülen bazı TRAElerin altta yatan patofizyolojik mekanizmalar nedeniyle önlenmesi pek mümkün görünmese de bazı reaksiyonların hemovijilans ile azaltılabileceğini gösteren çalışmamızın klinisyenleri ve hemovijilans birimlerini teşvik edeceğini umuyoruz. Hemovijilans çalışmalarıyla daha güvenli transfüzyon yapılmaya çalışılsa da en önemli konu kan bileşenlerine maruziyetin en aza indirilmesidir.

Makale detayları

The impact of hemovigilance studies on transfusion practices: Single centre experience

Yazarlar:

Samet Yaman | Gökhan Evren | Bilge Zihar | Emine Beköz | Yurdagül Kökcü | Abdulkerim Yıldız

Yayıncı:

Hitit University

Ana Başlıklar:

Hematoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 3, pp.349-355

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329542

pISSN:

2687-4717

hemovigilance

transfusion

reactionHemovijilans

Reaksiyon

Transfüzyon

Sayı

Makale detayları

The impact of hemovigilance studies on transfusion practices: Single centre experience

Yazarlar: Samet Yaman | Gökhan Evren | Bilge Zihar | Emine Beköz | Yurdagül Kökcü | Abdulkerim Yıldız

Yayıncı: Hitit University

Ana Başlıklar: Hematoloji

Dergi: Hitit Medical Journal Vol.6 Issue 3, pp.349-355

Belge Tipi: Makale

Yayın Tarihi: 10/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001329542

pISSN: 2687-4717

hemovigilance

transfusion

reactionHemovijilans

Reaksiyon

Transfüzyon

Sayı

Yazarlar:

Samet Yaman | Gökhan Evren | Bilge Zihar | Emine Beköz | Yurdagül Kökcü | Abdulkerim Yıldız

Yayıncı:

Hitit University

Ana Başlıklar:

Hematoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 3, pp.349-355

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329542

pISSN:

2687-4717