Investigation of ACTN3 rs1815739 Polymorphism,  Physical Characteristics, and Position—Relation in  Football Players: A Team Sample

N.A.

Makale detayları

Investigation of ACTN3 rs1815739 Polymorphism, Physical Characteristics, and Position—Relation in Football Players: A Team Sample

Yazarlar:

N.A.

Yayıncı:

Ataturk University

Ana Başlıklar:

Spor Hekimliği

Dergi:

Research in Sport Education and Sciences Vol.25 Issue 1, pp.14-18

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284885

pISSN:

2822-3527

Anahtar kelimeler:

Özet:

 We aimed to determine the alpha actin-3 gene rs1815739 polymorphism in professional footballers and to compare genotype and allele frequencies with sedentary individuals. Also, we aimed to determine the relationship between the genotypes of footballers and their positions. Twenty footballers participated in our study. Seventy-six participants without sports background were included in our study as the control group. DNA isolation was performed from blood samples using the PureLink DNA isolation kit according to the manufacturers procedures. rs1815739 polymorphism was performed using real-time polymerase chain reaction device. Statistical analyses of the obtained data were carried out with chi-square analysis using IBM Statistical Package for Social Sciences 21.0 IBM Statistical Package for Social Sciences Corp. program. A value of p  .05 was considered statistically significant. CC genotype was observed in 2 individuals 10, CT 35 in 7 individuals, and TT 55 in 11 individuals in footballers. In the control group, the CC, CT, and TT genotypes were determined as 15 19.7, 41 53.9, 20 26.4, respectively. The C allele was 11 27.5 in footballers and 71 46.71 in the control group; the T allele was found to be 29 72.5 in footballers and 81 53.29 in the control group. A statistically significant difference was found between the footballers and the control group in terms of genotype p.049 and allele p.028. It was determined that midfielders who require endurance are mostly in the TT genotype, while the sprinter strikers are in the CC genotype. Although the findings are compatible with the literature, similar studies should be planned with higher numbers.

 We aimed to determine the alpha actin-3 gene rs1815739 polymorphism in professional footballers and to compare genotype and allele frequencies with sedentary individuals. Also, we aimed to determine the relationship between the genotypes of footballers and their positions. Twenty footballers participated in our study. Seventy-six participants without sports background were included in our study as the control group. DNA isolation was performed from blood samples using the PureLink DNA isolation kit according to the manufacturers procedures. rs1815739 polymorphism was performed using real-time polymerase chain reaction device. Statistical analyses of the obtained data were carried out with chi-square analysis using IBM Statistical Package for Social Sciences 21.0 IBM Statistical Package for Social Sciences Corp. program. A value of p  .05 was considered statistically significant. CC genotype was observed in 2 individuals 10, CT 35 in 7 individuals, and TT 55 in 11 individuals in footballers. In the control group, the CC, CT, and TT genotypes were determined as 15 19.7, 41 53.9, 20 26.4, respectively. The C allele was 11 27.5 in footballers and 71 46.71 in the control group; the T allele was found to be 29 72.5 in footballers and 81 53.29 in the control group. A statistically significant difference was found between the footballers and the control group in terms of genotype p.049 and allele p.028. It was determined that midfielders who require endurance are mostly in the TT genotype, while the sprinter strikers are in the CC genotype. Although the findings are compatible with the literature, similar studies should be planned with higher numbers.

 We aimed to determine the alpha actin-3 gene rs1815739 polymorphism in professional footballers and to compare genotype and allele frequencies with sedentary individuals. Also, we aimed to determine the relationship between the genotypes of footballers and their positions. Twenty footballers participated in our study. Seventy-six participants without sports background were included in our study as the control group. DNA isolation was performed from blood samples using the PureLink DNA isolation kit according to the manufacturers procedures. rs1815739 polymorphism was performed using real-time polymerase chain reaction device. Statistical analyses of the obtained data were carried out with chi-square analysis using IBM Statistical Package for Social Sciences 21.0 IBM Statistical Package for Social Sciences Corp. program. A value of p  .05 was considered statistically significant. CC genotype was observed in 2 individuals 10, CT 35 in 7 individuals, and TT 55 in 11 individuals in footballers. In the control group, the CC, CT, and TT genotypes were determined as 15 19.7, 41 53.9, 20 26.4, respectively. The C allele was 11 27.5 in footballers and 71 46.71 in the control group; the T allele was found to be 29 72.5 in footballers and 81 53.29 in the control group. A statistically significant difference was found between the footballers and the control group in terms of genotype p.049 and allele p.028. It was determined that midfielders who require endurance are mostly in the TT genotype, while the sprinter strikers are in the CC genotype. Although the findings are compatible with the literature, similar studies should be planned with higher numbers.

 Çalışmamızda, profesyonel futbolcularda alfa aktinin-3 geni rs1815739 polimorfizmini belirlemeyi, genotip ve allel frekanslarını sedanter bireyler ile karşılaştırmayı hedefledik. Ayrıca futbolcuların genotipleri ile mevkileri arasındaki ilişkiyi saptamayı amaçladık. Çalışmamıza 20 futbolcu katılmıştır. Spor geçmişi olmayan 76 katılımcı kontrol grubu olarak çalışmamıza dahil olmuştur. DNA izolasyonu, kan örneklerinden PureLink DNA izolasyon kiti kullanılarak üretici firmanın prosedürlerine göre gerçekleştirilmiştir. rs1815739 polimorfizmi izole edilen DNA materyalinden Real-Time PCR cihazı ile gerçeklestirilmiştir. Elde edilen verilerin istatiksel analizlerini IBM SPSS 21.0 IBM Statistical Package for Social Sciences Corp., Armonk, NY, ABD programı kullanılarak kikare analizi ile gerçekleştirilmiştir. p  ,05 değeri istatiksel olarak anlamlı kabul edilmiştir. Futbolcularda 2 bireyde CC 10, 7 bireyde CT 35, 11 bireyde TT 55 genotipi gözlemlenmiştir. Kontrol grubunda CC, CT ve TT genotipleri sırasıyla 15 19,7, 41 53,9, 20 26,4 olarak tespit edilmiştir. C alleli futbolcularda 11 27,5, kontrol grubunda 71 46,71; T alleli ise futbolcularda 29 72,5, kontrol grubunda 81 53,29 olarak bulunmuştur. Futbolcu ile kontrol grubu arasında genotip p,049 ve allel p,028 bakımından istatistiksel olarak anlamlı fark bulunmuştur. Dayanıklılık gerektiren orta saha oyuncuları çoğunlukla TT genotipinde, sprinter özellikteki santraforlar ise CC genotipinde olduğu belirlenmiştir. Elde edilen bulgular literatürle uyum sağlamakla birlikte benzer çalışmaların daha yüksek sayılı planlanması gerekmektedir.

Makale detayları

Investigation of ACTN3 rs1815739 Polymorphism, Physical Characteristics, and Position—Relation in Football Players: A Team Sample

Yazarlar:

N.A.

Yayıncı:

Ataturk University

Ana Başlıklar:

Spor Hekimliği

Dergi:

Research in Sport Education and Sciences Vol.25 Issue 1, pp.14-18

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284885

pISSN:

2822-3527

Football

position

genetics

polymorphism

ACTN3

Futbol

mevki

genetik

polimorfizm

ACTN3

Sayı

Makale detayları

Yazarlar: N.A.

Yayıncı: Ataturk University

Ana Başlıklar: Spor Hekimliği

Dergi: Research in Sport Education and Sciences Vol.25 Issue 1, pp.14-18

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001284885

pISSN: 2822-3527

Sayı

Yazarlar:

N.A.

Yayıncı:

Ataturk University

Ana Başlıklar:

Spor Hekimliği

Dergi:

Research in Sport Education and Sciences Vol.25 Issue 1, pp.14-18

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284885

pISSN:

2822-3527