GREEN SYNTHESIS OF NEW AMINO ACID SCHIFF BASES AND THEIR BIOLOGICAL ACTIVITIES

Cigdem Yorur-Goreci; Zulal Demir; Nilay Altaş

doi:https://doi.org/10.18596/jotcsa.14900

Makale detayları

GREEN SYNTHESIS OF NEW AMINO ACID SCHIFF BASES AND THEIR BIOLOGICAL ACTIVITIES

Yazarlar:

Cigdem Yorur-Goreci | Zulal Demir | Nilay Altaş

Yayıncı:

Turkish Chemical Society

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2016 Vol.3 Issue 3, pp.15-24

Belge Tipi:

Makale

Yayın Tarihi:

1/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000503715

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.14900

Özet:

 


In this study, four new and two known amino acid Schiff base compounds derived from the condensation reaction of benzaldehyde, salicylaldehyde, pyrrole-2-carbaldehyde, pyridine-2-carbaldehyde, fluorene-2-carbaldehyde and terephthalaldehyde with 2-phenylglycine methyl ester hydrochloride have been synthesized by both conventional method and microwave irradiation protocol. The new compounds were characterized by FTIR, 1H-NMR, LC-MS and electronic spectral studies. A comparative study between conventional heating and microwave irradiation has also been reported. Based on these results, with the microwave synthesis, the yield of the products was increased from 37% upto 96% as compared to conventional method. By microwave, reactions were completed within 5.5-8.5 minutes and the products were obtained in good to high yields, with reduced time, waste, and formation byproduct. DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging effect were performed to determine antioxidant activities of the new compounds. All of the compounds exhibited significant activities in DPPH radical scavenging. 

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Makale detayları

GREEN SYNTHESIS OF NEW AMINO ACID SCHIFF BASES AND THEIR BIOLOGICAL ACTIVITIES

Yazarlar: Cigdem Yorur-Goreci | Zulal Demir | Nilay Altaş

Yayıncı: Turkish Chemical Society

Dergi: Journal of the Turkish Chemical Society Section A: Chemistry 2016 Vol.3 Issue 3, pp.15-24

Belge Tipi: Makale

Yayın Tarihi: 1/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000503715

Sıklık: Üç Aylık

eISSN: 2149-0120

DOI: https://doi.org/10.18596/jotcsa.14900

Sayı

Yazarlar:

Cigdem Yorur-Goreci | Zulal Demir | Nilay Altaş

Yayıncı:

Turkish Chemical Society

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2016 Vol.3 Issue 3, pp.15-24

Belge Tipi:

Makale

Yayın Tarihi:

1/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000503715

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.14900