The Evaluation of Basal Ganglia in Pediatric Patients with Cerebral Palsy Using Magnetic Resonance Histogram Analysis

Ferit Doğan; Mehmet Demir; Hüseyin Gümüş; Celil Yılmaz

Makale detayları

The Evaluation of Basal Ganglia in Pediatric Patients with Cerebral Palsy Using Magnetic Resonance Histogram Analysis

Yazarlar:

Ferit Doğan | Mehmet Demir | Hüseyin Gümüş | Celil Yılmaz

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.97-101

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325377

pISSN:

2148-8118

Anahtar kelimeler:

Özet:

 The aim of this study is to detect changes in the basal ganglia using magnetic resonance imaging MRI histogram in patients with cerebral palsy CP who do not have pathological signal changes in the basal ganglia on conventional MRI images. A retrospective evaluation was made of the images of 40 children with CP and 60 children with no significant intracranial findings on brain MRI examination. The histogram parameters of mean, variance, skewness, kurtosis, 1st percentile P, 10th P, 50th P, 90th P and 99th P were calculated for each patient and control group on the areas identified in the head of the thalamus, lentiform nucleus and nucleus caudatus and these were evaluated separately for each case. A significant difference was found between the groups in terms of the mean, kurtosis and 50th P values of histogram parameters obtained from the thalamus p0.001, p0.002, p0.025, respectively. A significant difference was found between the mean, skewness, kurtosis and 1st P values of histogram parameters obtained from the lentiform nuclei p0.021, p0.005, p0.015, p0.035, respectively. A significant difference was found between the mean, kurtosis, 90th P and 99th P values of the histogram parameters obtained from the head section of the nucleus caudatus p0.002, p0.03, p0.004, p0.042, respectively. Texture analysis can produce objective features that may indicate differences in the basal ganglia and thalamus in patients with CP. Texture analysis can identify changes in the basal ganglia in patients with CP who do not have pathological signal changes on conventional MRI images.

 The aim of this study is to detect changes in the basal ganglia using magnetic resonance imaging MRI histogram in patients with cerebral palsy CP who do not have pathological signal changes in the basal ganglia on conventional MRI images. A retrospective evaluation was made of the images of 40 children with CP and 60 children with no significant intracranial findings on brain MRI examination. The histogram parameters of mean, variance, skewness, kurtosis, 1st percentile P, 10th P, 50th P, 90th P and 99th P were calculated for each patient and control group on the areas identified in the head of the thalamus, lentiform nucleus and nucleus caudatus and these were evaluated separately for each case. A significant difference was found between the groups in terms of the mean, kurtosis and 50th P values of histogram parameters obtained from the thalamus p0.001, p0.002, p0.025, respectively. A significant difference was found between the mean, skewness, kurtosis and 1st P values of histogram parameters obtained from the lentiform nuclei p0.021, p0.005, p0.015, p0.035, respectively. A significant difference was found between the mean, kurtosis, 90th P and 99th P values of the histogram parameters obtained from the head section of the nucleus caudatus p0.002, p0.03, p0.004, p0.042, respectively. Texture analysis can produce objective features that may indicate differences in the basal ganglia and thalamus in patients with CP. Texture analysis can identify changes in the basal ganglia in patients with CP who do not have pathological signal changes on conventional MRI images.

 The aim of this study is to detect changes in the basal ganglia using magnetic resonance imaging MRI histogram in patients with cerebral palsy CP who do not have pathological signal changes in the basal ganglia on conventional MRI images. A retrospective evaluation was made of the images of 40 children with CP and 60 children with no significant intracranial findings on brain MRI examination. The histogram parameters of mean, variance, skewness, kurtosis, 1st percentile P, 10th P, 50th P, 90th P and 99th P were calculated for each patient and control group on the areas identified in the head of the thalamus, lentiform nucleus and nucleus caudatus and these were evaluated separately for each case. A significant difference was found between the groups in terms of the mean, kurtosis and 50th P values of histogram parameters obtained from the thalamus p0.001, p0.002, p0.025, respectively. A significant difference was found between the mean, skewness, kurtosis and 1st P values of histogram parameters obtained from the lentiform nuclei p0.021, p0.005, p0.015, p0.035, respectively. A significant difference was found between the mean, kurtosis, 90th P and 99th P values of the histogram parameters obtained from the head section of the nucleus caudatus p0.002, p0.03, p0.004, p0.042, respectively. Texture analysis can produce objective features that may indicate differences in the basal ganglia and thalamus in patients with CP. Texture analysis can identify changes in the basal ganglia in patients with CP who do not have pathological signal changes on conventional MRI images.

 Konvansiyonel manyetik rezonans görüntüleme MRG görüntülerinde bazal ganglionlarda patolojik sinyal değişiklikleri olmayan serebral palsili SP hastalarda MRG histogramını kullanarak bazal ganglionlardaki değişiklikleri tespit etmeyi amaçladık. Serebral palsili 40 çocuk ve beyin MRG incelemesinde anlamlı intrakraniyal bulgusu olmayan 60 çocuğun görüntüleri retrospektif olarak değerlendirildi. Ortalama, varyans, çarpıklık, basıklık, 1. yüzdelik P, 10. P, 50. P, 90. P ve 99. P histogram parametreleri her hasta ve kontrol grubu için talamus, lentiform ve kaudat nukleuslardan tanımlanan alanlarda hesaplandı ve her vaka için ayrı ayrı değerlendirildi. Talamustan elde edilen histogram parametrelerinin ortalama, basıklık ve 50. P değerleri açısından gruplar arasında anlamlı fark bulundu sırasıyla p0.001, p0.002, p0.025. Lentiform çekirdeklerden elde edilen histogram parametrelerinin ortalama, çarpıklık, basıklık ve 1. P değerleri arasında anlamlı bir fark bulunmuştur sırasıyla p0.021, p0.005, p0.015, p0.035. Nukleus kaudatustan elde edilen histogram parametrelerinin ortalama, basıklık, 90. P ve 99. P değerleri arasında anlamlı farklılık tespit edildi sırasıyla p0.002, p0.03, p0.004, p0.042. Doku analizi, serebral palsili hastalarda bazal ganglionlar ve talamustaki farklılıkları gösterebilecek objektif özellikler üretebilir. Doku analizi, konvansiyonel MRG görüntülerinde patolojik sinyal değişikliği olmayan SPli hastalarda bazal ganglionlardaki değişiklikleri tanımlayabilir.

Makale detayları

The Evaluation of Basal Ganglia in Pediatric Patients with Cerebral Palsy Using Magnetic Resonance Histogram Analysis

Yazarlar:

Ferit Doğan | Mehmet Demir | Hüseyin Gümüş | Celil Yılmaz

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.97-101

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325377

pISSN:

2148-8118

Basal ganglia

Texture analysis

Cerebral palsy

ThalamusBazal Ganglionlar

Doku Analizi

Serebral Palsi

Talamus

Sayı

Makale detayları

Yazarlar: Ferit Doğan | Mehmet Demir | Hüseyin Gümüş | Celil Yılmaz

Yayıncı: Mugla Sitki Kocman University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.97-101

Belge Tipi: Makale

Yayın Tarihi: 8/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001325377

pISSN: 2148-8118

Sayı

Yazarlar:

Ferit Doğan | Mehmet Demir | Hüseyin Gümüş | Celil Yılmaz

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.97-101

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325377

pISSN:

2148-8118