The Effect of Blood Base Deficit on Neonatal Convulsions and Amplitude Electroencephalography Measurements in Perinatal Asphyxia

Hüseyin Gümüş; Mehmet Kılıç

Makale detayları

The Effect of Blood Base Deficit on Neonatal Convulsions and Amplitude Electroencephalography Measurements in Perinatal Asphyxia

Yazarlar:

Hüseyin Gümüş | Mehmet Kılıç

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.207-214

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319481

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Objective: To determine the effect of blood pH levels and base deficit on neonatal convulsions and amplitude electroencephalography measurements in patients with perinatal asphyxia. Methods: This study included 102 patients monitored in the neonatal intensive care unit for perinatal asphyxia. Amplitude electroencephalography measurements and convulsions were recorded from all patients for 80 hours. Blood samples were taken in the umbilical artery for the pH analysis and calculation of base deficit. Results: The mean gestational age was 38.131.30 weeks with 6636 64.7  35.3, malefemale ratio. Fifty-seven 55.9 babies were delivered by normal spontaneous vaginal delivery, while 45 patients 44.1 had a history of cesarean delivery. There were significant differences between the mean base deficit and amplitude electroencephalography recordings at the first 24th, 48th, and 72nd hours KW32.819, p0.001; KW23.687, p0.001, and KW24.992, p0.001, respectively. Sixty-five 63.7 of the patients had neonatal convulsions. The mean base deficit was 20.644.70 mmolL and 17.482.92 mmolL in patients with and without seizures, respectively. The mean base deficit was significantly higher in patients with neonatal seizures Z3.912; p0.001. Conclusion: Our study showed patients with abnormal amplitude electroencephalography findings and epileptic electrical activity were found to have higher base deficits at the time of diagnosis. It suggests that high base deficit levels may have a negative effect on the neurodevelopmental process in the neonatal period.

 Objective: To determine the effect of blood pH levels and base deficit on neonatal convulsions and amplitude electroencephalography measurements in patients with perinatal asphyxia. Methods: This study included 102 patients monitored in the neonatal intensive care unit for perinatal asphyxia. Amplitude electroencephalography measurements and convulsions were recorded from all patients for 80 hours. Blood samples were taken in the umbilical artery for the pH analysis and calculation of base deficit. Results: The mean gestational age was 38.131.30 weeks with 6636 64.7  35.3, malefemale ratio. Fifty-seven 55.9 babies were delivered by normal spontaneous vaginal delivery, while 45 patients 44.1 had a history of cesarean delivery. There were significant differences between the mean base deficit and amplitude electroencephalography recordings at the first 24th, 48th, and 72nd hours KW32.819, p0.001; KW23.687, p0.001, and KW24.992, p0.001, respectively. Sixty-five 63.7 of the patients had neonatal convulsions. The mean base deficit was 20.644.70 mmolL and 17.482.92 mmolL in patients with and without seizures, respectively. The mean base deficit was significantly higher in patients with neonatal seizures Z3.912; p0.001. Conclusion: Our study showed patients with abnormal amplitude electroencephalography findings and epileptic electrical activity were found to have higher base deficits at the time of diagnosis. It suggests that high base deficit levels may have a negative effect on the neurodevelopmental process in the neonatal period.

 Objective: To determine the effect of blood pH levels and base deficit on neonatal convulsions and amplitude electroencephalography measurements in patients with perinatal asphyxia. Methods: This study included 102 patients monitored in the neonatal intensive care unit for perinatal asphyxia. Amplitude electroencephalography measurements and convulsions were recorded from all patients for 80 hours. Blood samples were taken in the umbilical artery for the pH analysis and calculation of base deficit. Results: The mean gestational age was 38.131.30 weeks with 6636 64.7  35.3, malefemale ratio. Fifty-seven 55.9 babies were delivered by normal spontaneous vaginal delivery, while 45 patients 44.1 had a history of cesarean delivery. There were significant differences between the mean base deficit and amplitude electroencephalography recordings at the first 24th, 48th, and 72nd hours KW32.819, p0.001; KW23.687, p0.001, and KW24.992, p0.001, respectively. Sixty-five 63.7 of the patients had neonatal convulsions. The mean base deficit was 20.644.70 mmolL and 17.482.92 mmolL in patients with and without seizures, respectively. The mean base deficit was significantly higher in patients with neonatal seizures Z3.912; p0.001. Conclusion: Our study showed patients with abnormal amplitude electroencephalography findings and epileptic electrical activity were found to have higher base deficits at the time of diagnosis. It suggests that high base deficit levels may have a negative effect on the neurodevelopmental process in the neonatal period.

 Objective: To determine the effect of blood pH levels and base deficit on neonatal convulsions and amplitude electroencephalography measurements in patients with perinatal asphyxia. Methods: This study included 102 patients monitored in the neonatal intensive care unit for perinatal asphyxia. Amplitude electroencephalography measurements and convulsions were recorded from all patients for 80 hours. Blood samples were taken in the umbilical artery for the pH analysis and calculation of base deficit. Results: The mean gestational age was 38.131.30 weeks with 6636 64.7  35.3, malefemale ratio. Fifty-seven 55.9 babies were delivered by normal spontaneous vaginal delivery, while 45 patients 44.1 had a history of cesarean delivery. There were significant differences between the mean base deficit and amplitude electroencephalography recordings at the first 24th, 48th, and 72nd hours KW32.819, p0.001; KW23.687, p0.001, and KW24.992, p0.001, respectively. Sixty-five 63.7 of the patients had neonatal convulsions. The mean base deficit was 20.644.70 mmolL and 17.482.92 mmolL in patients with and without seizures, respectively. The mean base deficit was significantly higher in patients with neonatal seizures Z3.912; p0.001. Conclusion: Our study showed patients with abnormal amplitude electroencephalography findings and epileptic electrical activity were found to have higher base deficits at the time of diagnosis. It suggests that high base deficit levels may have a negative effect on the neurodevelopmental process in the neonatal period.

Makale detayları

The Effect of Blood Base Deficit on Neonatal Convulsions and Amplitude Electroencephalography Measurements in Perinatal Asphyxia

Yazarlar: Hüseyin Gümüş | Mehmet Kılıç

Yayıncı: Dicle University

Ana Başlıklar: Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi: Dicle Tıp Dergisi Vol.51 Issue 2, pp.207-214

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001319481

pISSN: 1300-2945

Amplitude electroencephalography

base deficit

convulsion

perinatal asphyxia

Sayı

Yazarlar:

Hüseyin Gümüş | Mehmet Kılıç

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.207-214

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319481

pISSN:

1300-2945