Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

Muhammad Zakariyyah AUMEERUDDY; Zaahira AUMEERUDDY-ELALFİ; Hudaa NEETOO; Gökhan ZENGİN; Bianca FİBRİCH; Sunelle RADEMAN; Analike Blom Van STADEN; Karina SZUMAN; İsa Anina LAMBRECHTS; Namrita LALL; Mohamad Fawzi MAHOMOODALLY

Makale detayları

Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

Yazarlar:

Muhammad Zakariyyah AUMEERUDDY | Zaahira AUMEERUDDY-ELALFİ | Hudaa NEETOO | Gökhan ZENGİN | Bianca FİBRİCH | Sunelle RADEMAN | Analike Blom Van STADEN | Karina SZUMAN | İsa Anina LAMBRECHTS | Namrita LALL | Mohamad Fawzi MAHOMOODALLY

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.89-99

Belge Tipi:

Makale

Yayın Tarihi:

11/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000513055

Sıklık:

Aylık

eISSN:

2587-2087

Özet:

 


This study was designed to evaluate and
correlate the biological, phytochemical, and physicochemical properties of two
NSS (Nigella sativa seed) oils (N1 and N2). The biological activity was evaluated
in terms of antibacterial, antioxidant (nitric oxide scavenging), antielastase,
antityrosinase, antimelanogenic, and anticancer activity. Physicochemical
properties including colour, total soluble solids (TSS), and density were also
investigated. N2 exhibited higher antibacterial, NO scavenging, extracellular
antimelanogenic, and anticancer activity against the HeLa cell line compared to
N1, which showed higher antityrosinase activity. TPC (total phenolic content)
and TFC (total flavonoid content) of N1 were significantly higher than N2 while
TTC (total tannin content) was higher in N2. In fact, TTC was strongly
correlated (R=1.000) with the antioxidant, extracellular antimelanogenic, and
HeLa cell inhibitory activity. To conclude, NSS oil may be considered as a
complementary and alternative therapy in the management of infectious and
chronic diseases but warrants further in vivo pharmacological validation and
toxicological analysis.


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Makale detayları

Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

Yazarlar: Muhammad Zakariyyah AUMEERUDDY | Zaahira AUMEERUDDY-ELALFİ | Hudaa NEETOO | Gökhan ZENGİN | Bianca FİBRİCH | Sunelle RADEMAN | Analike Blom Van STADEN | Karina SZUMAN | İsa Anina LAMBRECHTS | Namrita LALL | Mohamad Fawzi MAHOMOODALLY

Yayıncı: Istanbul University

Ana Başlıklar: Sağlık teşvikleri

Dergi: İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.89-99

Belge Tipi: Makale

Yayın Tarihi: 11/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000513055

Sıklık: Aylık

eISSN: 2587-2087

Sayı

Yazarlar:

Muhammad Zakariyyah AUMEERUDDY | Zaahira AUMEERUDDY-ELALFİ | Hudaa NEETOO | Gökhan ZENGİN | Bianca FİBRİCH | Sunelle RADEMAN | Analike Blom Van STADEN | Karina SZUMAN | İsa Anina LAMBRECHTS | Namrita LALL | Mohamad Fawzi MAHOMOODALLY

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

İstanbul Journal of Pharmacy 2018 Vol.48 Issue 3, pp.89-99

Belge Tipi:

Makale

Yayın Tarihi:

11/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000513055

Sıklık:

Aylık

eISSN:

2587-2087