The relationship of serotonin level with syndrome X and coronary artery disease

İbrahim Aktaş; Hasan Arı; Mehmet Demir; Yasemin Üstündağ

Makale detayları

The relationship of serotonin level with syndrome X and coronary artery disease

Yazarlar:

İbrahim Aktaş | Hasan Arı | Mehmet Demir | Yasemin Üstündağ

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.6 Issue 3, pp.203-209

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001318180

pISSN:

2718-0115

Anahtar kelimeler:

Özet:

 Aims: Platelets secrete serotonin 5-hydroxytryptamine which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and proliferation of smooth muscle cells. We thought serotonin which relation with coronary artery disease CAD has been shown in various data might be important for etiology and diagnosis of cardiac syndrome X CSX whichs physiopathology has not been elucidated yet. The aim of the study is to investigate relationship between serotonin level with CSX and stabile coronary artery disease. Methods: Serum serotonin levels were measured by micro ELİSA procedure in three group of patients who underwent coronary angiography. First group consisted of 30 patients 17 male, 13 female, mean age 60.56.1 who has diagnosed CSX, second group consisted 22 patients 11 male, 11 female, mean age 60.56.1 who has diagnosed stable coronary artery disease and third group consisted 28 patients 10 male, 18 female, mean age 56.610 comprised the control group. All three groups of patients demographic, biochemical, hematological and echocardiographic data were recorded. Results: The three groups were similar with respect to age, sex, body mass index and the frequencies of diabetes mellitus and smokingp.016. We detected average serum serotonin levels 49.7 ngml in syndrome X group, 41.8 ngml in CAD group and 44.8 ngml in control group. These values are not statistically significant between the groups monitoredp.91. Conclusion: The serotonin level of of CSX patients, stabile coronary artery disease patients and control group patients were measured in the serum which seperated from peripheral venous blood. Statistically significant difference in serum serotonin levels couldnt be detected between these three group.

 Aims: Platelets secrete serotonin 5-hydroxytryptamine which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and proliferation of smooth muscle cells. We thought serotonin which relation with coronary artery disease CAD has been shown in various data might be important for etiology and diagnosis of cardiac syndrome X CSX whichs physiopathology has not been elucidated yet. The aim of the study is to investigate relationship between serotonin level with CSX and stabile coronary artery disease. Methods: Serum serotonin levels were measured by micro ELİSA procedure in three group of patients who underwent coronary angiography. First group consisted of 30 patients 17 male, 13 female, mean age 60.56.1 who has diagnosed CSX, second group consisted 22 patients 11 male, 11 female, mean age 60.56.1 who has diagnosed stable coronary artery disease and third group consisted 28 patients 10 male, 18 female, mean age 56.610 comprised the control group. All three groups of patients demographic, biochemical, hematological and echocardiographic data were recorded. Results: The three groups were similar with respect to age, sex, body mass index and the frequencies of diabetes mellitus and smokingp.016. We detected average serum serotonin levels 49.7 ngml in syndrome X group, 41.8 ngml in CAD group and 44.8 ngml in control group. These values are not statistically significant between the groups monitoredp.91. Conclusion: The serotonin level of of CSX patients, stabile coronary artery disease patients and control group patients were measured in the serum which seperated from peripheral venous blood. Statistically significant difference in serum serotonin levels couldnt be detected between these three group.

 Aims: Platelets secrete serotonin 5-hydroxytryptamine which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and proliferation of smooth muscle cells. We thought serotonin which relation with coronary artery disease CAD has been shown in various data might be important for etiology and diagnosis of cardiac syndrome X CSX whichs physiopathology has not been elucidated yet. The aim of the study is to investigate relationship between serotonin level with CSX and stabile coronary artery disease. Methods: Serum serotonin levels were measured by micro ELİSA procedure in three group of patients who underwent coronary angiography. First group consisted of 30 patients 17 male, 13 female, mean age 60.56.1 who has diagnosed CSX, second group consisted 22 patients 11 male, 11 female, mean age 60.56.1 who has diagnosed stable coronary artery disease and third group consisted 28 patients 10 male, 18 female, mean age 56.610 comprised the control group. All three groups of patients demographic, biochemical, hematological and echocardiographic data were recorded. Results: The three groups were similar with respect to age, sex, body mass index and the frequencies of diabetes mellitus and smokingp.016. We detected average serum serotonin levels 49.7 ngml in syndrome X group, 41.8 ngml in CAD group and 44.8 ngml in control group. These values are not statistically significant between the groups monitoredp.91. Conclusion: The serotonin level of of CSX patients, stabile coronary artery disease patients and control group patients were measured in the serum which seperated from peripheral venous blood. Statistically significant difference in serum serotonin levels couldnt be detected between these three group.

 Aims: Platelets secrete serotonin 5-hydroxytryptamine which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and proliferation of smooth muscle cells. We thought serotonin which relation with coronary artery disease CAD has been shown in various data might be important for etiology and diagnosis of cardiac syndrome X CSX whichs physiopathology has not been elucidated yet. The aim of the study is to investigate relationship between serotonin level with CSX and stabile coronary artery disease. Methods: Serum serotonin levels were measured by micro ELİSA procedure in three group of patients who underwent coronary angiography. First group consisted of 30 patients 17 male, 13 female, mean age 60.56.1 who has diagnosed CSX, second group consisted 22 patients 11 male, 11 female, mean age 60.56.1 who has diagnosed stable coronary artery disease and third group consisted 28 patients 10 male, 18 female, mean age 56.610 comprised the control group. All three groups of patients demographic, biochemical, hematological and echocardiographic data were recorded. Results: The three groups were similar with respect to age, sex, body mass index and the frequencies of diabetes mellitus and smokingp.016. We detected average serum serotonin levels 49.7 ngml in syndrome X group, 41.8 ngml in CAD group and 44.8 ngml in control group. These values are not statistically significant between the groups monitoredp.91. Conclusion: The serotonin level of of CSX patients, stabile coronary artery disease patients and control group patients were measured in the serum which seperated from peripheral venous blood. Statistically significant difference in serum serotonin levels couldnt be detected between these three group.

Makale detayları

The relationship of serotonin level with syndrome X and coronary artery disease

Yazarlar:

İbrahim Aktaş | Hasan Arı | Mehmet Demir | Yasemin Üstündağ

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.6 Issue 3, pp.203-209

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001318180

pISSN:

2718-0115

Serotonin

Cardiac Syndrome X

Coronary Artery Disease

Sayı

Makale detayları

The relationship of serotonin level with syndrome X and coronary artery disease

Yazarlar: İbrahim Aktaş | Hasan Arı | Mehmet Demir | Yasemin Üstündağ

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Kardiyoloji

Dergi: Anatolian Current Medical Journal Vol.6 Issue 3, pp.203-209

Belge Tipi: Makale

Yayın Tarihi: 5/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001318180

pISSN: 2718-0115

Serotonin

Cardiac Syndrome X

Coronary Artery Disease

Sayı

Yazarlar:

İbrahim Aktaş | Hasan Arı | Mehmet Demir | Yasemin Üstündağ

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.6 Issue 3, pp.203-209

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001318180

pISSN:

2718-0115