Is Bacterial Profile and Antibiotics Resisance Changed in The Patients with Lower Respiratory tract İnfeciton Hospitalized to Tertiary Chest Diseases Hospital?

Gülru Polat; Güneş Şenol; Aysu Ayrancı; Damla Serçe Unat; Filiz Güldaval; Merve Ayık Türk; İhsan Topaloğlu; Ömer Selim Unat; Gülistan Karadeniz; Fatma Demirci Üçsular; Enver Yalnız; Melih Büyükşirin; Mahmut Mete Demirel

Makale detayları

Is Bacterial Profile and Antibiotics Resisance Changed in The Patients with Lower Respiratory tract İnfeciton Hospitalized to Tertiary Chest Diseases Hospital?

Yazarlar:

Gülru Polat | Güneş Şenol | Aysu Ayrancı | Damla Serçe Unat | Filiz Güldaval | Merve Ayık Türk | İhsan Topaloğlu | Ömer Selim Unat | Gülistan Karadeniz | Fatma Demirci Üçsular | Enver Yalnız | Melih Büyükşirin | Mahmut Mete Demirel

Yayıncı:

Bolu Abant Izzet Baysal University

Ana Başlıklar:

Clinical Sciences

Dergi:

Abant Medical Journal Vol.12 Issue 1, pp.10-18

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287812

pISSN:

1305-4392

Anahtar kelimeler:

Özet:

 Objective: Lower respiratory tract infections LRTIs are a major cause of mortality and morbidity in hospital admissions and inpatients. In this study, it was aimed to investigate the isolated factors, antibiotic resistance rates, previous hospitalization, and antibiotic use of patients in hospitalized LRTI cases. Materials and Methods: In this study, the demographic and clinical characteristics, microbiological features of the patients who were hospitalized with the diagnosis of LRTI and found to have growth in the cultures of the respiratory tract samples between 2013-2018 were investigated using a cross-sectional descriptive method. Results: We analyzed 484 agents isolated from 469 patients and their antibiotic resistance profiles. The mean age of the cases was 63.9 years. The most isolated agent was Pseudomonas aeruginosa n 220; 45.5. One 6 penicillin and three 17 macrolide resistant isolates were detected in 17 isolated strains of S. pneumonia. H. influenza was isolated in 34 cases. In the case, 8 ampicillin and 12 quinolone resistance were reported. Conclusion: We concluded that when starting empirical antibiotic therapy, it is necessary to consider increasing quinolone resistance and P. aeruginosa being the causative agent in almost half of the cases, questioning the frequency of previous hospitalizations and antibiotic use, and considering local antibiotic resistance patterns.

 Objective: Lower respiratory tract infections LRTIs are a major cause of mortality and morbidity in hospital admissions and inpatients. In this study, it was aimed to investigate the isolated factors, antibiotic resistance rates, previous hospitalization, and antibiotic use of patients in hospitalized LRTI cases. Materials and Methods: In this study, the demographic and clinical characteristics, microbiological features of the patients who were hospitalized with the diagnosis of LRTI and found to have growth in the cultures of the respiratory tract samples between 2013-2018 were investigated using a cross-sectional descriptive method. Results: We analyzed 484 agents isolated from 469 patients and their antibiotic resistance profiles. The mean age of the cases was 63.9 years. The most isolated agent was Pseudomonas aeruginosa n 220; 45.5. One 6 penicillin and three 17 macrolide resistant isolates were detected in 17 isolated strains of S. pneumonia. H. influenza was isolated in 34 cases. In the case, 8 ampicillin and 12 quinolone resistance were reported. Conclusion: We concluded that when starting empirical antibiotic therapy, it is necessary to consider increasing quinolone resistance and P. aeruginosa being the causative agent in almost half of the cases, questioning the frequency of previous hospitalizations and antibiotic use, and considering local antibiotic resistance patterns.

 Objective: Lower respiratory tract infections LRTIs are a major cause of mortality and morbidity in hospital admissions and inpatients. In this study, it was aimed to investigate the isolated factors, antibiotic resistance rates, previous hospitalization, and antibiotic use of patients in hospitalized LRTI cases. Materials and Methods: In this study, the demographic and clinical characteristics, microbiological features of the patients who were hospitalized with the diagnosis of LRTI and found to have growth in the cultures of the respiratory tract samples between 2013-2018 were investigated using a cross-sectional descriptive method. Results: We analyzed 484 agents isolated from 469 patients and their antibiotic resistance profiles. The mean age of the cases was 63.9 years. The most isolated agent was Pseudomonas aeruginosa n 220; 45.5. One 6 penicillin and three 17 macrolide resistant isolates were detected in 17 isolated strains of S. pneumonia. H. influenza was isolated in 34 cases. In the case, 8 ampicillin and 12 quinolone resistance were reported. Conclusion: We concluded that when starting empirical antibiotic therapy, it is necessary to consider increasing quinolone resistance and P. aeruginosa being the causative agent in almost half of the cases, questioning the frequency of previous hospitalizations and antibiotic use, and considering local antibiotic resistance patterns.

 Amaç: Alt solunum yolu enfeksiyonları ASYE hastaneye ayaktan başvurularda ve yatan hastalarda önemli mortalite ve morbidite nedenidir. Bu çalışmada hastaneye yatırılan ASYE olgularında izole edilen etkenler, antibiyotik direnç oranları, hastaların önceden hastaneye yatış ve antibiyotik kullanım durumlarının araştırılması amaçlanmıştır. Gereç ve Yöntemler: Bu çalışmada 2013-2018 yılları arasında hastanemize ASYE tanısı ile yatırılan ve solunum yolu örneği kültürlerinde üreme saptanan olguların demografik özellikleri, hastane yatış sayıları, antibiyotik kullanım öyküleri ile kültürle elde edilmiş etkenleri ve antibiyotik dirençleri kesitsel tanımlayıcı metotla araştırılmıştır. Bulgular: 469 hastadan izole edilen 484 etkeni ve bu etkenlerin antibiyotik direnç profillerini inceledik. Olguların yaş ortalaması 63,9 idi. En fazla izole edilen etken Pseudomonas aeruginosa n 220; 45,5 idi. İzole edilen 17 S. pneumonia kökeninde bir 6 penisilin, üç 17 makrolid dirençli izolat saptandı. H. influenza 34 olguda izole edildi. Olguda 8 ampisilin ve 12 kinolon direnci rapor edildi. Sonuç: Ampirik antibiyotik tedavisi başlanırken, artan kinolon direncinin ve olguların yarısına yakınında P. aeruginosa etken olduğunun göz önüne alınması, özellikle daha önce hastaneye yatış sıklığı ve antibiyotik kullanma öyküsünün sorgulanması ve lokal antibiyotik direnç paternlerinin göz önüne alınmasının gerekli olduğu sonucuna vardık.

Makale detayları

Is Bacterial Profile and Antibiotics Resisance Changed in The Patients with Lower Respiratory tract İnfeciton Hospitalized to Tertiary Chest Diseases Hospital?

Yazarlar:

Gülru Polat | Güneş Şenol | Aysu Ayrancı | Damla Serçe Unat | Filiz Güldaval | Merve Ayık Türk | İhsan Topaloğlu | Ömer Selim Unat | Gülistan Karadeniz | Fatma Demirci Üçsular | Enver Yalnız | Melih Büyükşirin | Mahmut Mete Demirel

Yayıncı:

Bolu Abant Izzet Baysal University

Ana Başlıklar:

Clinical Sciences

Dergi:

Abant Medical Journal Vol.12 Issue 1, pp.10-18

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287812

pISSN:

1305-4392

Lower Respiratory Tract Infection

Antibiotic Resistance

Bacteria Profile

HospitalizedAlt Solunum Yolu Enfeksiyonu

Antibiyotik Direnci

Bakteri Profili

Hastane Yatışı

Sayı

Makale detayları

Yazarlar: Gülru Polat | Güneş Şenol | Aysu Ayrancı | Damla Serçe Unat | Filiz Güldaval | Merve Ayık Türk | İhsan Topaloğlu | Ömer Selim Unat | Gülistan Karadeniz | Fatma Demirci Üçsular | Enver Yalnız | Melih Büyükşirin | Mahmut Mete Demirel

Yayıncı: Bolu Abant Izzet Baysal University

Ana Başlıklar: Clinical Sciences

Dergi: Abant Medical Journal Vol.12 Issue 1, pp.10-18

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001287812

pISSN: 1305-4392

Sayı

Yazarlar:

Gülru Polat | Güneş Şenol | Aysu Ayrancı | Damla Serçe Unat | Filiz Güldaval | Merve Ayık Türk | İhsan Topaloğlu | Ömer Selim Unat | Gülistan Karadeniz | Fatma Demirci Üçsular | Enver Yalnız | Melih Büyükşirin | Mahmut Mete Demirel

Yayıncı:

Bolu Abant Izzet Baysal University

Ana Başlıklar:

Clinical Sciences

Dergi:

Abant Medical Journal Vol.12 Issue 1, pp.10-18

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287812

pISSN:

1305-4392