Pulmonary and cardiac involvement in patients with rheumatoid arthritis and ankylosing spondylitis

Ahmet Hüsrev Tekeli

Makale detayları

Pulmonary and cardiac involvement in patients with rheumatoid arthritis and ankylosing spondylitis

Yazarlar:

Ahmet Hüsrev Tekeli

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

The European Research Journal Vol.9 Issue 2, pp.291-300

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282994

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: Our aim is to study the disease activity status, laboratory data and to determine the frequency of cardiac and pulmonary findings in patients with Rheumatoid arthritis RA and ankylosing spondylitis AS. Methods: Forty-five AS patients and 78 RA patients took part in the study. The C-reactive protein CRP, erythrocyte sedimentation rate ESR, albumin, creatinine, ALT, leukocyte, neutrophil ratio, hemoglobin, platelet, rheumatoid factor RF, and anti-cyclic citrullinated peptide anti-CCP levels were measured. In addition, the patients thoracic computed tomography, high-resolution computed tomography HRCT, echocardiography ECHO, and pulmonary function test PFT results were evaluated. Disease activity was assessed with the Disease Activity Score-28 DAS-28 in RA patients, whereas the Bath Ankylosing Spondylitis Disease Activity Index BASDAI was used in patients with AS. Results: The relationship between the anti-CCP value and gender was significant in RA patients. Significant differences were present between gender and hemoglobin value in RA and AS patients, whereas no significant differences were determined between CRP, ESR, platelet, and DAS-28 values. There was a significant difference between RF and ESR values in RA patients, whereas no significant difference was present between CRP, leukocyte, DAS-28, hemoglobin, and platelet values. Pulmonary involvement was determined in 35.7 of RA patients and 4.2 of AS patients. The difference between these was statistically significant. Conclusions: The most common pulmonary involvement is millimetric nonspecific nodule and the most common lesion among ECHO findings was left ventricular diastolic dysfunction in RA and AS patients. In RA, no significant difference was determined between PFT and DAS-28 results, as a result, the disease activity will not directly indicate pulmonary involvement.

 Objectives: Our aim is to study the disease activity status, laboratory data and to determine the frequency of cardiac and pulmonary findings in patients with Rheumatoid arthritis RA and ankylosing spondylitis AS. Methods: Forty-five AS patients and 78 RA patients took part in the study. The C-reactive protein CRP, erythrocyte sedimentation rate ESR, albumin, creatinine, ALT, leukocyte, neutrophil ratio, hemoglobin, platelet, rheumatoid factor RF, and anti-cyclic citrullinated peptide anti-CCP levels were measured. In addition, the patients thoracic computed tomography, high-resolution computed tomography HRCT, echocardiography ECHO, and pulmonary function test PFT results were evaluated. Disease activity was assessed with the Disease Activity Score-28 DAS-28 in RA patients, whereas the Bath Ankylosing Spondylitis Disease Activity Index BASDAI was used in patients with AS. Results: The relationship between the anti-CCP value and gender was significant in RA patients. Significant differences were present between gender and hemoglobin value in RA and AS patients, whereas no significant differences were determined between CRP, ESR, platelet, and DAS-28 values. There was a significant difference between RF and ESR values in RA patients, whereas no significant difference was present between CRP, leukocyte, DAS-28, hemoglobin, and platelet values. Pulmonary involvement was determined in 35.7 of RA patients and 4.2 of AS patients. The difference between these was statistically significant. Conclusions: The most common pulmonary involvement is millimetric nonspecific nodule and the most common lesion among ECHO findings was left ventricular diastolic dysfunction in RA and AS patients. In RA, no significant difference was determined between PFT and DAS-28 results, as a result, the disease activity will not directly indicate pulmonary involvement.

 Objectives: Our aim is to study the disease activity status, laboratory data and to determine the frequency of cardiac and pulmonary findings in patients with Rheumatoid arthritis RA and ankylosing spondylitis AS. Methods: Forty-five AS patients and 78 RA patients took part in the study. The C-reactive protein CRP, erythrocyte sedimentation rate ESR, albumin, creatinine, ALT, leukocyte, neutrophil ratio, hemoglobin, platelet, rheumatoid factor RF, and anti-cyclic citrullinated peptide anti-CCP levels were measured. In addition, the patients thoracic computed tomography, high-resolution computed tomography HRCT, echocardiography ECHO, and pulmonary function test PFT results were evaluated. Disease activity was assessed with the Disease Activity Score-28 DAS-28 in RA patients, whereas the Bath Ankylosing Spondylitis Disease Activity Index BASDAI was used in patients with AS. Results: The relationship between the anti-CCP value and gender was significant in RA patients. Significant differences were present between gender and hemoglobin value in RA and AS patients, whereas no significant differences were determined between CRP, ESR, platelet, and DAS-28 values. There was a significant difference between RF and ESR values in RA patients, whereas no significant difference was present between CRP, leukocyte, DAS-28, hemoglobin, and platelet values. Pulmonary involvement was determined in 35.7 of RA patients and 4.2 of AS patients. The difference between these was statistically significant. Conclusions: The most common pulmonary involvement is millimetric nonspecific nodule and the most common lesion among ECHO findings was left ventricular diastolic dysfunction in RA and AS patients. In RA, no significant difference was determined between PFT and DAS-28 results, as a result, the disease activity will not directly indicate pulmonary involvement.

 Objectives: Our aim is to study the disease activity status, laboratory data and to determine the frequency of cardiac and pulmonary findings in patients with Rheumatoid arthritis RA and ankylosing spondylitis AS. Methods: Forty-five AS patients and 78 RA patients took part in the study. The C-reactive protein CRP, erythrocyte sedimentation rate ESR, albumin, creatinine, ALT, leukocyte, neutrophil ratio, hemoglobin, platelet, rheumatoid factor RF, and anti-cyclic citrullinated peptide anti-CCP levels were measured. In addition, the patients thoracic computed tomography, high-resolution computed tomography HRCT, echocardiography ECHO, and pulmonary function test PFT results were evaluated. Disease activity was assessed with the Disease Activity Score-28 DAS-28 in RA patients, whereas the Bath Ankylosing Spondylitis Disease Activity Index BASDAI was used in patients with AS. Results: The relationship between the anti-CCP value and gender was significant in RA patients. Significant differences were present between gender and hemoglobin value in RA and AS patients, whereas no significant differences were determined between CRP, ESR, platelet, and DAS-28 values. There was a significant difference between RF and ESR values in RA patients, whereas no significant difference was present between CRP, leukocyte, DAS-28, hemoglobin, and platelet values. Pulmonary involvement was determined in 35.7 of RA patients and 4.2 of AS patients. The difference between these was statistically significant. Conclusions: The most common pulmonary involvement is millimetric nonspecific nodule and the most common lesion among ECHO findings was left ventricular diastolic dysfunction in RA and AS patients. In RA, no significant difference was determined between PFT and DAS-28 results, as a result, the disease activity will not directly indicate pulmonary involvement.

Makale detayları

Pulmonary and cardiac involvement in patients with rheumatoid arthritis and ankylosing spondylitis

Yazarlar: Ahmet Hüsrev Tekeli

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Rheumatology and Arthritis

Dergi: The European Research Journal Vol.9 Issue 2, pp.291-300

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282994

pISSN: 2149-3189

Rheumatoid arthritis

ankylosing spondylitis

high-resolution computed tomography

Sayı

Yazarlar:

Ahmet Hüsrev Tekeli

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

The European Research Journal Vol.9 Issue 2, pp.291-300

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282994

pISSN:

2149-3189