A trend analysis of inflammatory bowel disease in non-endemic era (1993-2023)

Yavuz Çağır; Muhammed Bahaddin Durak; Orhan Coşkun; İlyas Tenlik; Öykü Tayfur Yürekli; Mevlüt Hamamcı; Ali Atay; Oğuz Özturk; Abdurrezzak Yılmaz; Ahmet Burak Fedai; Volkan Gökbulut; Çağdaş Kalkan; Ömer Öztürk; Aylin Demirezer Bolat; Mahmut Yüksel; Hasan Tankut Köseoğlu; İlhami Yüksel

Makale detayları

A trend analysis of inflammatory bowel disease in non-endemic era (1993-2023)

Yazarlar:

Yavuz Çağır | Muhammed Bahaddin Durak | Orhan Coşkun | İlyas Tenlik | Öykü Tayfur Yürekli | Mevlüt Hamamcı | Ali Atay | Oğuz Özturk | Abdurrezzak Yılmaz | Ahmet Burak Fedai | Volkan Gökbulut | Çağdaş Kalkan | Ömer Öztürk | Aylin Demirezer Bolat | Mahmut Yüksel | Hasan Tankut Köseoğlu | İlhami Yüksel

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Journal of Health Sciences and Medicine Vol.7 Issue 5, pp.587-592

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001328468

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aims: In this study, we aimed to evaluate the demographic and epidemiological trends of ulcerative colitis UC and Crohns disease CD in non-endemic era for inflammatory bowel disease IBD during the past three decades. Methods: UC and CD patients who had follow-up at least 6 months between June 1993 and February 2023 were evaluated retrospectively. Electronic medical databases, personal queries and IBD registries have all been used to collection data on the clinical and demographic characteristic of all patients. Results: A total of 1549 adult patients with UC and CD were admitted to study. UC was diagnosed in 873 56.4 patients male 538, 61.6 and CD was diagnosed in 676 43.6 patients male 404, 59.8. Median total disease duration was 8.3 years in UC group, as well as 6.8 years in CD group. In patients with UC, proctitis was 154 17.6, left sided colitis was 410 47 and extensive colitis was 309 35.4. In CD patients, ileal involvement was found in 297 43.9, colonic in 76 11.2, ileo-colonic in 299 44.2 and isolated upper gastrointestinal involvement in 4 0.6 cases. 529 78.3 patients had inflammatory disease non-stenosing non-penetrating behavior, 45 6.7 had stenosing behavior, 102 15.1 had penetrating behavior, as well as 196 29 patients had perianal disease. Mesalazine 658 75.4 and thiopurine 397 45.5 were the most frequently used conventional treatments for UC, while thiopurine 304 45 was most commonly used for CD patients. In the last two-decade, proportion of the biologic usage were 27.9 and 32.1 in UC patients 28.5 and 31.4 in CD patients respectively. Over the three decades, abdominal surgery was 49.2, 27.8 and 36.3 in CD and colectomy rates was 2.0, 2.7 and 3.7 in UC patients. While the rate of UC patients has slightly decreased to 98 61.6, 401 58.5 and 374 53 frequency of CD patients has increased to 61 38.4, 284 41.5 and 331 47. Over the course of three decades, there were more UC patients than CD patients, however proportion of UCCD has been continuously decreased 1.61, 1.41 and 1.13 for three decades respectively. Conclusion: Our study showed that the frequency of UC and CD has significantly increased during the previous three decades in non-endemic era for IBD. While the frequency of UC patients has slightly decreased, that of CD patients has steadily increased over the past three decades. Although the use of biologics has significantly increased, proportions of the major abdominal surgeries and colectomies has not prominently changed.

 Aims: In this study, we aimed to evaluate the demographic and epidemiological trends of ulcerative colitis UC and Crohns disease CD in non-endemic era for inflammatory bowel disease IBD during the past three decades. Methods: UC and CD patients who had follow-up at least 6 months between June 1993 and February 2023 were evaluated retrospectively. Electronic medical databases, personal queries and IBD registries have all been used to collection data on the clinical and demographic characteristic of all patients. Results: A total of 1549 adult patients with UC and CD were admitted to study. UC was diagnosed in 873 56.4 patients male 538, 61.6 and CD was diagnosed in 676 43.6 patients male 404, 59.8. Median total disease duration was 8.3 years in UC group, as well as 6.8 years in CD group. In patients with UC, proctitis was 154 17.6, left sided colitis was 410 47 and extensive colitis was 309 35.4. In CD patients, ileal involvement was found in 297 43.9, colonic in 76 11.2, ileo-colonic in 299 44.2 and isolated upper gastrointestinal involvement in 4 0.6 cases. 529 78.3 patients had inflammatory disease non-stenosing non-penetrating behavior, 45 6.7 had stenosing behavior, 102 15.1 had penetrating behavior, as well as 196 29 patients had perianal disease. Mesalazine 658 75.4 and thiopurine 397 45.5 were the most frequently used conventional treatments for UC, while thiopurine 304 45 was most commonly used for CD patients. In the last two-decade, proportion of the biologic usage were 27.9 and 32.1 in UC patients 28.5 and 31.4 in CD patients respectively. Over the three decades, abdominal surgery was 49.2, 27.8 and 36.3 in CD and colectomy rates was 2.0, 2.7 and 3.7 in UC patients. While the rate of UC patients has slightly decreased to 98 61.6, 401 58.5 and 374 53 frequency of CD patients has increased to 61 38.4, 284 41.5 and 331 47. Over the course of three decades, there were more UC patients than CD patients, however proportion of UCCD has been continuously decreased 1.61, 1.41 and 1.13 for three decades respectively. Conclusion: Our study showed that the frequency of UC and CD has significantly increased during the previous three decades in non-endemic era for IBD. While the frequency of UC patients has slightly decreased, that of CD patients has steadily increased over the past three decades. Although the use of biologics has significantly increased, proportions of the major abdominal surgeries and colectomies has not prominently changed.

 Aims: In this study, we aimed to evaluate the demographic and epidemiological trends of ulcerative colitis UC and Crohns disease CD in non-endemic era for inflammatory bowel disease IBD during the past three decades. Methods: UC and CD patients who had follow-up at least 6 months between June 1993 and February 2023 were evaluated retrospectively. Electronic medical databases, personal queries and IBD registries have all been used to collection data on the clinical and demographic characteristic of all patients. Results: A total of 1549 adult patients with UC and CD were admitted to study. UC was diagnosed in 873 56.4 patients male 538, 61.6 and CD was diagnosed in 676 43.6 patients male 404, 59.8. Median total disease duration was 8.3 years in UC group, as well as 6.8 years in CD group. In patients with UC, proctitis was 154 17.6, left sided colitis was 410 47 and extensive colitis was 309 35.4. In CD patients, ileal involvement was found in 297 43.9, colonic in 76 11.2, ileo-colonic in 299 44.2 and isolated upper gastrointestinal involvement in 4 0.6 cases. 529 78.3 patients had inflammatory disease non-stenosing non-penetrating behavior, 45 6.7 had stenosing behavior, 102 15.1 had penetrating behavior, as well as 196 29 patients had perianal disease. Mesalazine 658 75.4 and thiopurine 397 45.5 were the most frequently used conventional treatments for UC, while thiopurine 304 45 was most commonly used for CD patients. In the last two-decade, proportion of the biologic usage were 27.9 and 32.1 in UC patients 28.5 and 31.4 in CD patients respectively. Over the three decades, abdominal surgery was 49.2, 27.8 and 36.3 in CD and colectomy rates was 2.0, 2.7 and 3.7 in UC patients. While the rate of UC patients has slightly decreased to 98 61.6, 401 58.5 and 374 53 frequency of CD patients has increased to 61 38.4, 284 41.5 and 331 47. Over the course of three decades, there were more UC patients than CD patients, however proportion of UCCD has been continuously decreased 1.61, 1.41 and 1.13 for three decades respectively. Conclusion: Our study showed that the frequency of UC and CD has significantly increased during the previous three decades in non-endemic era for IBD. While the frequency of UC patients has slightly decreased, that of CD patients has steadily increased over the past three decades. Although the use of biologics has significantly increased, proportions of the major abdominal surgeries and colectomies has not prominently changed.

 Aims: In this study, we aimed to evaluate the demographic and epidemiological trends of ulcerative colitis UC and Crohns disease CD in non-endemic era for inflammatory bowel disease IBD during the past three decades. Methods: UC and CD patients who had follow-up at least 6 months between June 1993 and February 2023 were evaluated retrospectively. Electronic medical databases, personal queries and IBD registries have all been used to collection data on the clinical and demographic characteristic of all patients. Results: A total of 1549 adult patients with UC and CD were admitted to study. UC was diagnosed in 873 56.4 patients male 538, 61.6 and CD was diagnosed in 676 43.6 patients male 404, 59.8. Median total disease duration was 8.3 years in UC group, as well as 6.8 years in CD group. In patients with UC, proctitis was 154 17.6, left sided colitis was 410 47 and extensive colitis was 309 35.4. In CD patients, ileal involvement was found in 297 43.9, colonic in 76 11.2, ileo-colonic in 299 44.2 and isolated upper gastrointestinal involvement in 4 0.6 cases. 529 78.3 patients had inflammatory disease non-stenosing non-penetrating behavior, 45 6.7 had stenosing behavior, 102 15.1 had penetrating behavior, as well as 196 29 patients had perianal disease. Mesalazine 658 75.4 and thiopurine 397 45.5 were the most frequently used conventional treatments for UC, while thiopurine 304 45 was most commonly used for CD patients. In the last two-decade, proportion of the biologic usage were 27.9 and 32.1 in UC patients 28.5 and 31.4 in CD patients respectively. Over the three decades, abdominal surgery was 49.2, 27.8 and 36.3 in CD and colectomy rates was 2.0, 2.7 and 3.7 in UC patients. While the rate of UC patients has slightly decreased to 98 61.6, 401 58.5 and 374 53 frequency of CD patients has increased to 61 38.4, 284 41.5 and 331 47. Over the course of three decades, there were more UC patients than CD patients, however proportion of UCCD has been continuously decreased 1.61, 1.41 and 1.13 for three decades respectively. Conclusion: Our study showed that the frequency of UC and CD has significantly increased during the previous three decades in non-endemic era for IBD. While the frequency of UC patients has slightly decreased, that of CD patients has steadily increased over the past three decades. Although the use of biologics has significantly increased, proportions of the major abdominal surgeries and colectomies has not prominently changed.

Makale detayları

A trend analysis of inflammatory bowel disease in non-endemic era (1993-2023)

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Journal of Health Sciences and Medicine Vol.7 Issue 5, pp.587-592

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001328468

pISSN:

2636-8579

Inflammatory bowel disease

ulcerative colitis

crohn’s disease

three decades

Sayı

Makale detayları

A trend analysis of inflammatory bowel disease in non-endemic era (1993-2023)

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Gastroenteroloji ve Hepatoloji

Dergi: Journal of Health Sciences and Medicine Vol.7 Issue 5, pp.587-592

Belge Tipi: Makale

Yayın Tarihi: 9/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001328468

pISSN: 2636-8579

Inflammatory bowel disease

ulcerative colitis

crohn’s disease

three decades

Sayı

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Journal of Health Sciences and Medicine Vol.7 Issue 5, pp.587-592

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001328468

pISSN:

2636-8579