EvaEvaluation of glucose challenge and oral glucose tolerance test results in pregnancy and estimation of prevalence of gestational diabetes mellitus at Sema Hospital in İstanbul

Ahmet Ruhi TORAMAN; Ahmet GÜREL; Zeynep ULUSAL; Gülnihal BÜLBÜL; Ayşe Gülçin DEMİRDÖVEN; Melek UZUN; Ali ÖZCAN; Muzaffer ÇAKMAK

Makale detayları

EvaEvaluation of glucose challenge and oral glucose tolerance test results in pregnancy and estimation of prevalence of gestational diabetes mellitus at Sema Hospital in İstanbul

Yazarlar:

Ahmet Ruhi TORAMAN | Ahmet GÜREL | Zeynep ULUSAL | Gülnihal BÜLBÜL | Ayşe Gülçin DEMİRDÖVEN | Melek UZUN | Ali ÖZCAN | Muzaffer ÇAKMAK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue Sup.1, pp.1235-1240

Belge Tipi:

Makale

Yayın Tarihi:

11/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

This study was designed to evaluate glucose screening and oral glucose tolerance test results, and to assess the prevalence of gestational diabetes in pregnant patients admitted to our hospital.  Materials and methods: This retrospective study was carried out at Sema Hospital in İstanbul, Turkey. The study subjects were recruited between January 2006 and August 2009. A glucose challenge test (GCT) was given to 1681 pregnant women and based on the results 494 went on to take an oral glucose tolerance test (OGTT). A diagnosis of gestational diabetes mellitus (GDM) was made according to the criteria defined by the National Diabetes Data Group.  Results: Out of the 1681 pregnant women tested, 58 were diagnosed with gestational diabetes. Pregnant women with GDM had GCT results greater than or equal to 145 mg/dL. While the percentage of GCT false positives was 87.8% when the cut-off value was taken to be 140 mg/dL, it was calculated to be 84.3% when the cut-off value was taken to be 145 mg/dL. For the 140 mg/dL cut-off value of GCT, specificity was 100% and sensitivity was 4.3%, and for the 145 mg/dL cut-off value of GCT, specificity was 98.3% and sensitivity was 28.3%.  Conclusion: The prevalence value in this study was calculated at 3.45%. Pregnant women diagnosed with GDM had GCT results higher than 145 mg/dL. When the cut-off value was increased from 140 mg/dL to 145 mg/dL, a decrease was observed in false positives, and an increase was observed in sensitivity.

 

This study was designed to evaluate glucose screening and oral glucose tolerance test results, and to assess the prevalence of gestational diabetes in pregnant patients admitted to our hospital.  Materials and methods: This retrospective study was carried out at Sema Hospital in İstanbul, Turkey. The study subjects were recruited between January 2006 and August 2009. A glucose challenge test (GCT) was given to 1681 pregnant women and based on the results 494 went on to take an oral glucose tolerance test (OGTT). A diagnosis of gestational diabetes mellitus (GDM) was made according to the criteria defined by the National Diabetes Data Group.  Results: Out of the 1681 pregnant women tested, 58 were diagnosed with gestational diabetes. Pregnant women with GDM had GCT results greater than or equal to 145 mg/dL. While the percentage of GCT false positives was 87.8% when the cut-off value was taken to be 140 mg/dL, it was calculated to be 84.3% when the cut-off value was taken to be 145 mg/dL. For the 140 mg/dL cut-off value of GCT, specificity was 100% and sensitivity was 4.3%, and for the 145 mg/dL cut-off value of GCT, specificity was 98.3% and sensitivity was 28.3%.  Conclusion: The prevalence value in this study was calculated at 3.45%. Pregnant women diagnosed with GDM had GCT results higher than 145 mg/dL. When the cut-off value was increased from 140 mg/dL to 145 mg/dL, a decrease was observed in false positives, and an increase was observed in sensitivity.

Makale detayları

EvaEvaluation of glucose challenge and oral glucose tolerance test results in pregnancy and estimation of prevalence of gestational diabetes mellitus at Sema Hospital in İstanbul

Yazarlar:

Ahmet Ruhi TORAMAN | Ahmet GÜREL | Zeynep ULUSAL | Gülnihal BÜLBÜL | Ayşe Gülçin DEMİRDÖVEN | Melek UZUN | Ali ÖZCAN | Muzaffer ÇAKMAK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue Sup.1, pp.1235-1240

Belge Tipi:

Makale

Yayın Tarihi:

11/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Gestation

gestational diabetes

glucose screening test

oral glucose tolerance test

prevalence

Sayı

Makale detayları

EvaEvaluation of glucose challenge and oral glucose tolerance test results in pregnancy and estimation of prevalence of gestational diabetes mellitus at Sema Hospital in İstanbul

Yazarlar: Ahmet Ruhi TORAMAN | Ahmet GÜREL | Zeynep ULUSAL | Gülnihal BÜLBÜL | Ayşe Gülçin DEMİRDÖVEN | Melek UZUN | Ali ÖZCAN | Muzaffer ÇAKMAK

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2012 Vol.42 Issue Sup.1, pp.1235-1240

Belge Tipi: Makale

Yayın Tarihi: 11/2011

Belge Dili: Türkçe

Document ID (Org No.): 2000754360

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Gestation

gestational diabetes

glucose screening test

oral glucose tolerance test

prevalence

Sayı

Yazarlar:

Ahmet Ruhi TORAMAN | Ahmet GÜREL | Zeynep ULUSAL | Gülnihal BÜLBÜL | Ayşe Gülçin DEMİRDÖVEN | Melek UZUN | Ali ÖZCAN | Muzaffer ÇAKMAK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue Sup.1, pp.1235-1240

Belge Tipi:

Makale

Yayın Tarihi:

11/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144