Chronic liver diseases and iron: a concise review with emphasis on hypotransferrinemia and hypohepcidinemia

Naciye Şemnur BÜYÜKAŞIK; Yahya BÜYÜKAŞIK

Makale detayları

Chronic liver diseases and iron: a concise review with emphasis on hypotransferrinemia and hypohepcidinemia

Yazarlar:

Naciye Şemnur BÜYÜKAŞIK | Yahya BÜYÜKAŞIK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1281-1291

Belge Tipi:

Makale

Yayın Tarihi:

9/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000751771

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Iron studies in chronic liver diseases (CLDs) have a long history. Currently we can mention certainties, uncertainties, and hopes related to this topic. It is certain that iron metabolism problems and hepatic siderosis are frequent in CLDs and they get more frequent as CLD progresses, but true iron overload is rare. There are conflicting literature data on the mechanism of siderosis, the role of iron in CLD pathogenesis, and the potential benefits of iron removal. We may hope that pharmacological approaches targeting iron metabolism disorders of CLD will be actively evaluated in the future. In this review, we aimed to present a general outlook of this extensively studied topic.

Makale detayları

Chronic liver diseases and iron: a concise review with emphasis on hypotransferrinemia and hypohepcidinemia

Yazarlar: Naciye Şemnur BÜYÜKAŞIK | Yahya BÜYÜKAŞIK

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1281-1291

Belge Tipi: Makale

Yayın Tarihi: 9/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000751771

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Naciye Şemnur BÜYÜKAŞIK | Yahya BÜYÜKAŞIK

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1281-1291

Belge Tipi:

Makale

Yayın Tarihi:

9/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000751771

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144