Assessment of antioxidant, antibacterial, antimycobacterial, and antifungal activities of some plants used as folk remedies in Turkey against dermatophytes and yeast-like fungi

Didem DELİORMAN ORHAN; Berrin ÖZÇELİK; Sanem HOŞBAŞ; Mecit VURAL

Makale detayları

Assessment of antioxidant, antibacterial, antimycobacterial, and antifungal activities of some plants used as folk remedies in Turkey against dermatophytes and yeast-like fungi

Yazarlar:

Didem DELİORMAN ORHAN | Berrin ÖZÇELİK | Sanem HOŞBAŞ | Mecit VURAL

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2012 Vol.36 Issue 6, pp.672-686

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000812553

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

Twenty-seven aqueous extracts obtained from 21 plants used in the treatment of respiratory tract infections as folk remedies in Turkey were investigated for their relative total phenolic contents and antioxidant, antibacterial, antimycobacterial, and antifungal activities. Antibacterial and antifungal activities against dermatophytes and yeast-like fungi were determined using the microdilution method. Antibacterial activity of all extracts was more pronounced against gram-positive bacteria than against gram-negative bacteria. These extracts also exhibited higher antifungal activity against Candida krusei than ketaconazole. Six extracts displayed antidermatophytic activity against Epidermophyton floccosum, while only 3 extracts were highly active against Trichophyton rubrum. The extracts showed strong activity against both Mycobacterium tuberculosis and Mycobacterium avium, except for the Teucrium polium, Urtica dioica, Salvia fruticosa, S. verticillata, Rosa canina (flower, shoot, and root), Rubus sanctus, and Crepis foetida extracts. Additionally, all extracts exhibited antioxidant activity in DPPH assay except for the Primula vulgaris, Ononis spinosa, Nepeta italica, Hedera helix, Lantana camara (orange flowers), U. dioica, and C. foetida extracts. The highest total phenolic content was observed in R. canina root extract. No correlation was observed between biological activities and the amount of phenolic compounds. All plants used in this study could be potential sources of new antimicrobial agents.

 

Twenty-seven aqueous extracts obtained from 21 plants used in the treatment of respiratory tract infections as folk remedies in Turkey were investigated for their relative total phenolic contents and antioxidant, antibacterial, antimycobacterial, and antifungal activities. Antibacterial and antifungal activities against dermatophytes and yeast-like fungi were determined using the microdilution method. Antibacterial activity of all extracts was more pronounced against gram-positive bacteria than against gram-negative bacteria. These extracts also exhibited higher antifungal activity against Candida krusei than ketaconazole. Six extracts displayed antidermatophytic activity against Epidermophyton floccosum, while only 3 extracts were highly active against Trichophyton rubrum. The extracts showed strong activity against both Mycobacterium tuberculosis and Mycobacterium avium, except for the Teucrium polium, Urtica dioica, Salvia fruticosa, S. verticillata, Rosa canina (flower, shoot, and root), Rubus sanctus, and Crepis foetida extracts. Additionally, all extracts exhibited antioxidant activity in DPPH assay except for the Primula vulgaris, Ononis spinosa, Nepeta italica, Hedera helix, Lantana camara (orange flowers), U. dioica, and C. foetida extracts. The highest total phenolic content was observed in R. canina root extract. No correlation was observed between biological activities and the amount of phenolic compounds. All plants used in this study could be potential sources of new antimicrobial agents.

Makale detayları

Assessment of antioxidant, antibacterial, antimycobacterial, and antifungal activities of some plants used as folk remedies in Turkey against dermatophytes and yeast-like fungi

Yazarlar:

Didem DELİORMAN ORHAN | Berrin ÖZÇELİK | Sanem HOŞBAŞ | Mecit VURAL

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2012 Vol.36 Issue 6, pp.672-686

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000812553

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Key words: Antioxidant activity

antimicrobial activity

total phenolic content

Sayı

Makale detayları

Assessment of antioxidant, antibacterial, antimycobacterial, and antifungal activities of some plants used as folk remedies in Turkey against dermatophytes and yeast-like fungi

Yazarlar: Didem DELİORMAN ORHAN | Berrin ÖZÇELİK | Sanem HOŞBAŞ | Mecit VURAL

Yayıncı: TUBITAK

Ana Başlıklar: Yaşam bilimleri

Dergi: Turkish Journal of Biology 2012 Vol.36 Issue 6, pp.672-686

Belge Tipi: Makale

Yayın Tarihi: 5/2012

Belge Dili: İngilizce

Document ID (Org No.): 2000812553

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Key words: Antioxidant activity

antimicrobial activity

total phenolic content

Sayı

Yazarlar:

Didem DELİORMAN ORHAN | Berrin ÖZÇELİK | Sanem HOŞBAŞ | Mecit VURAL

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2012 Vol.36 Issue 6, pp.672-686

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000812553

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152