Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells

Giray Buğra AKBABA

doi:https://doi.org/10.18596/jotcsa.974814

Makale detayları

Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells

Yazarlar:

Giray Buğra AKBABA

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

İnsan psikolojisi

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2021 Vol.8 Issue 4, pp.1145-1152

Belge Tipi:

Makale

Yayın Tarihi:

11/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000502137

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.974814

Özet:

 

Cerium(IV) oxide (CeO2) is widely used in industrial fields such as biomedical, glass, electronics, automotive, and pharmacology. In this study, the cytotoxic effects on human peripheral blood cultures of two forms of cerium(IV) oxide with different particle sizes (Bulk-sized Cerium(IV) oxide: BC and Nano-sized Cerium(IV) oxide: NC) in concentrations range of 0.001-200 ppm were investigated. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay were used to determine the cytotoxicity of these forms. According to the test results, it was determined that both forms caused severe cytotoxicity at all concentrations studied. It was observed that cytotoxicity increased with increasing concentration. NCs are more toxic at all concentrations except 100 and 200 ppm concentrations.

Makale detayları

Comparison of the cytotoxic effects of bulk and nanosized CeO2 on lymphocyte cells

Yazarlar: Giray Buğra AKBABA

Yayıncı: Turkish Chemical Society

Ana Başlıklar: İnsan psikolojisi

Dergi: Journal of the Turkish Chemical Society Section A: Chemistry 2021 Vol.8 Issue 4, pp.1145-1152

Belge Tipi: Makale

Yayın Tarihi: 11/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000502137

Sıklık: Üç Aylık

eISSN: 2149-0120

DOI: https://doi.org/10.18596/jotcsa.974814

Sayı

Yazarlar:

Giray Buğra AKBABA

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

İnsan psikolojisi

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2021 Vol.8 Issue 4, pp.1145-1152

Belge Tipi:

Makale

Yayın Tarihi:

11/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000502137

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.974814