Evaluation of Clinical and Laboratory Findings in Patients with Brucellosis

Necati Mumcu; Yusuf Özdemir; Nagehan Damar

Makale detayları

Evaluation of Clinical and Laboratory Findings in Patients with Brucellosis

Yazarlar:

Necati Mumcu | Yusuf Özdemir | Nagehan Damar

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Mikrobiyoloji

Dergi:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.51-61

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344994

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: The purpose of this study is to evaluate the demographic data, laboratory and clinical findings and organ involvement of patients diagnosed with brucellosis. Materials and Methods: The patients were divided into groups according to sex femalemale and age 40 years40 years and 30 years, 31-44 years, 45-59 years, and 60 years. Results: A total of 238 patients were assessed. Among those, 57.5 n137 were male, and the mean age was 43.815.0 years. Arthralgia 93.7, n223, myalgia 84.9, n202, and fatigue 84.5, n201 were the most common clinical symptoms. In female patients, myalgia 92.1 vs. 79.6, p0.008, fatigue 92.1 vs. 78.8, p0.005, headache 38.6 vs. 25.5, p0.031, and nausea 32.7 vs. 13.9, p0.001 were more common, whereas loss of appetite 43.5 vs. 59.9, p0.013 was less common. Weight loss 48.0 vs. 34.3, p0.034 and sacroiliitis 13.2 vs. 5.0, p0.029 were more common, whereas spondylodiscitis 2.0 vs. 9.3, p0.039 was less common in younger patients 40 years. Weight loss was more common in the 30 age group compared to the 31-44 age 55.8 vs. 32.8, p0.013 and 45-69 age groups 55.8 vs. 35.3, p0.019. Fever was less common in the 30 age group compared to the 45-59 age group 32.7 vs. 54.1, p0.015. Conclusion: In endemic areas, brucellosis should be considered in the differential diagnosis of patients with arthralgia, myalgia, fatigue, leukopenia or leukocytosis, and elevated ESR and CRP. Patients 40 years with brucellosis should be evaluated for sacroiliitis, and patients 40 years should be evaluated for spondylodiscitis complications.

 Purpose: The purpose of this study is to evaluate the demographic data, laboratory and clinical findings and organ involvement of patients diagnosed with brucellosis. Materials and Methods: The patients were divided into groups according to sex femalemale and age 40 years40 years and 30 years, 31-44 years, 45-59 years, and 60 years. Results: A total of 238 patients were assessed. Among those, 57.5 n137 were male, and the mean age was 43.815.0 years. Arthralgia 93.7, n223, myalgia 84.9, n202, and fatigue 84.5, n201 were the most common clinical symptoms. In female patients, myalgia 92.1 vs. 79.6, p0.008, fatigue 92.1 vs. 78.8, p0.005, headache 38.6 vs. 25.5, p0.031, and nausea 32.7 vs. 13.9, p0.001 were more common, whereas loss of appetite 43.5 vs. 59.9, p0.013 was less common. Weight loss 48.0 vs. 34.3, p0.034 and sacroiliitis 13.2 vs. 5.0, p0.029 were more common, whereas spondylodiscitis 2.0 vs. 9.3, p0.039 was less common in younger patients 40 years. Weight loss was more common in the 30 age group compared to the 31-44 age 55.8 vs. 32.8, p0.013 and 45-69 age groups 55.8 vs. 35.3, p0.019. Fever was less common in the 30 age group compared to the 45-59 age group 32.7 vs. 54.1, p0.015. Conclusion: In endemic areas, brucellosis should be considered in the differential diagnosis of patients with arthralgia, myalgia, fatigue, leukopenia or leukocytosis, and elevated ESR and CRP. Patients 40 years with brucellosis should be evaluated for sacroiliitis, and patients 40 years should be evaluated for spondylodiscitis complications.

 Purpose: The purpose of this study is to evaluate the demographic data, laboratory and clinical findings and organ involvement of patients diagnosed with brucellosis. Materials and Methods: The patients were divided into groups according to sex femalemale and age 40 years40 years and 30 years, 31-44 years, 45-59 years, and 60 years. Results: A total of 238 patients were assessed. Among those, 57.5 n137 were male, and the mean age was 43.815.0 years. Arthralgia 93.7, n223, myalgia 84.9, n202, and fatigue 84.5, n201 were the most common clinical symptoms. In female patients, myalgia 92.1 vs. 79.6, p0.008, fatigue 92.1 vs. 78.8, p0.005, headache 38.6 vs. 25.5, p0.031, and nausea 32.7 vs. 13.9, p0.001 were more common, whereas loss of appetite 43.5 vs. 59.9, p0.013 was less common. Weight loss 48.0 vs. 34.3, p0.034 and sacroiliitis 13.2 vs. 5.0, p0.029 were more common, whereas spondylodiscitis 2.0 vs. 9.3, p0.039 was less common in younger patients 40 years. Weight loss was more common in the 30 age group compared to the 31-44 age 55.8 vs. 32.8, p0.013 and 45-69 age groups 55.8 vs. 35.3, p0.019. Fever was less common in the 30 age group compared to the 45-59 age group 32.7 vs. 54.1, p0.015. Conclusion: In endemic areas, brucellosis should be considered in the differential diagnosis of patients with arthralgia, myalgia, fatigue, leukopenia or leukocytosis, and elevated ESR and CRP. Patients 40 years with brucellosis should be evaluated for sacroiliitis, and patients 40 years should be evaluated for spondylodiscitis complications.

 Amaç: Bu çalışmanın amacı bruselloz tanısı konulan hastaların demografik verilerini, klinik ve laboratuvar bulgularını ve organ tutulumlarını değerlendirmektir. Araçlar ve Yöntem: Hastalar cinsiyete kadınerkek ve yaşa 40 yıl40 yıl ve 30 yıl, 31-44 yıl, 45-59 yıl ve 60 yıl göre gruplara ayrıldı. Bulgular: Toplam 238 hasta değerlendirildi. Bunların 57.5i n137 erkekti ve yaş ortalaması 43.815.0 yıldı. En sık görülen klinik semptomlar artralji 93.7, n223, miyalji 84.9, n202 ve yorgunluk 84.5, n201 idi. Kadın hastalarda miyalji 92.1e karşı 79.6, p0.008, yorgunluk 92.1e karşı 78.8, p0.005, baş ağrısı 38.6ya karşı 25.5, p0.031 ve bulantı 32.7ye karşı 13.9, p0.001 daha yaygındı, iştahsızlık 43.5e karşı 59.9, p0.013 ise daha az yaygındı. Daha genç hastalarda 40 yaş kilo kaybı 48.0e karşı 34.3, p0.034 ve sakroileit 13.2ye karşı 5.0, p0.029 daha yaygındı, spondilodiskit 2.0ye karşı 9.3, p0.039 ise daha az yaygındı. Kilo kaybı 30 yaş grubunda 31-44 yaş grubuna 55.8 - 32.8, p0.013 ve 45-69 yaş grubuna 55.8 - 35.3, p0.019 göre daha yaygındı. Ateş 30 yaş grubunda 45-59 yaş grubuna 32.7 - 54.1, p0.015 göre daha az yaygındı. Sonuç: Endemik bölgelerde, artralji, miyalji, yorgunluk, lökopeni veya lökositoz ve yüksek ESR ve CRPli hastaların ayırıcı tanısında bruselloz düşünülmelidir. Brusellozlu 40 yaş hastalar sakroiliit açısından değerlendirilmeli ve 40 yaş hastalar spondilodiskit komplikasyonları açısından değerlendirilmelidir.

Makale detayları

Evaluation of Clinical and Laboratory Findings in Patients with Brucellosis

Yazarlar:

Necati Mumcu | Yusuf Özdemir | Nagehan Damar

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Mikrobiyoloji

Dergi:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.51-61

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344994

pISSN:

2619-9203

age

brucella

gender

sacroiliitis

spondylodiscitisbrusella

cinsiyet

sakroileit

spondilodiskit

yaş

Sayı

Makale detayları

Yazarlar: Necati Mumcu | Yusuf Özdemir | Nagehan Damar

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Mikrobiyoloji

Dergi: Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.51-61

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344994

pISSN: 2619-9203

Sayı

Yazarlar:

Necati Mumcu | Yusuf Özdemir | Nagehan Damar

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Mikrobiyoloji

Dergi:

Ahi Evran Tıp Dergisi Vol.9 Issue 1, pp.51-61

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344994

pISSN:

2619-9203