Neuronal Differentiation in The Cerebral Cortex  of The Rat: A Golgi-Cox Study

Necdet DEMİR

Makale detayları

Neuronal Differentiation in The Cerebral Cortex of The Rat: A Golgi-Cox Study

Yazarlar:

Necdet DEMİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 5, pp.481-490

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758234

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

The development of cerebral  cortex neurons has been studied in different  stages of pre- and postnatal periods of rats.  In order to show the neuronal processes, the  Golgi-Cox impregnation technique was used.  The first neuronal process development was  observed in the cranial and caudal poles of  the cerebral cortex during the 15th prenatal  day and continued spreading from the lateral  regions and poles towards the dorsocentral  regions of the hemispheres. The cells which  showed the first impregnation in the cerebral  cortex, were bipolar cells and their bodies  were located in the deep regions of the  hemisphere wall. Primitive multipolar cells,  which were seen in the superficial regions on  the 17th prenatal day, dispersed to the  deeper regions during the following days of  gestation. The neurons showing  impregnations formed cell groups during the  19th prenatal day. These cells were arranged  on an axis; whose perikaryons were touching  each other. At the beginning of the postnatal  period, they often appeared to be in the  deeper regions, laminae V-VI of the cortex,  later they were observed in the upper  regions. Probably, a "starter cell" created  cellular inductive effects, resulting in these  celular accumulations. After birth, cells  separated from these groups according to the  maturation level of their cellular and  neuropilic contents, cerebral growth and the  increase in number and length of neuron  processes.  As a result, in the course of the prenatal  development of the cerebral cortex,  consisting of cell proliferation and migration,  we observed differentiation and maturation  activities. The periods, in which  differentiation and maturation occur, are  predominantly late prenatal and postnatal  periods. In addition, functionally related cells  differentiate and mature in the same cell  groups.

 

The development of cerebral  cortex neurons has been studied in different  stages of pre- and postnatal periods of rats.  In order to show the neuronal processes, the  Golgi-Cox impregnation technique was used.  The first neuronal process development was  observed in the cranial and caudal poles of  the cerebral cortex during the 15th prenatal  day and continued spreading from the lateral  regions and poles towards the dorsocentral  regions of the hemispheres. The cells which  showed the first impregnation in the cerebral  cortex, were bipolar cells and their bodies  were located in the deep regions of the  hemisphere wall. Primitive multipolar cells,  which were seen in the superficial regions on  the 17th prenatal day, dispersed to the  deeper regions during the following days of  gestation. The neurons showing  impregnations formed cell groups during the  19th prenatal day. These cells were arranged  on an axis; whose perikaryons were touching  each other. At the beginning of the postnatal  period, they often appeared to be in the  deeper regions, laminae V-VI of the cortex,  later they were observed in the upper  regions. Probably, a "starter cell" created  cellular inductive effects, resulting in these  celular accumulations. After birth, cells  separated from these groups according to the  maturation level of their cellular and  neuropilic contents, cerebral growth and the  increase in number and length of neuron  processes.  As a result, in the course of the prenatal  development of the cerebral cortex,  consisting of cell proliferation and migration,  we observed differentiation and maturation  activities. The periods, in which  differentiation and maturation occur, are  predominantly late prenatal and postnatal  periods. In addition, functionally related cells  differentiate and mature in the same cell  groups.

Makale detayları

Neuronal Differentiation in The Cerebral Cortex of The Rat: A Golgi-Cox Study

Yazarlar:

Necdet DEMİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 5, pp.481-490

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758234

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Development

cerebral cortex

neuron

rat.

Sayı

Makale detayları

Neuronal Differentiation in The Cerebral Cortex of The Rat: A Golgi-Cox Study

Yazarlar: Necdet DEMİR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1998 Vol.28 Issue 5, pp.481-490

Belge Tipi: Makale

Yayın Tarihi: 4/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000758234

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Development

cerebral cortex

neuron

rat.

Sayı

Yazarlar:

Necdet DEMİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 5, pp.481-490

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758234

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144