Evaluation of Inflation, Neutrophil Lymphocyte and Platelet Lymphocyte Ratios with Other Parameters in Patients with Remarkable Leg Syndrome

Hüseyin Duru; Gül Duru; İhsan Asker

Makale detayları

Evaluation of Inflation, Neutrophil Lymphocyte and Platelet Lymphocyte Ratios with Other Parameters in Patients with Remarkable Leg Syndrome

Yazarlar:

Hüseyin Duru | Gül Duru | İhsan Asker

Yayıncı:

Karyay Karadeniz Yayımcılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Black Sea Journal of Health Science Vol.6 Issue 2, pp.270-273

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287286

pISSN:

2619-9041

Anahtar kelimeler:

Özet:

 Restless Legs Syndrome RLS is a sleep disorder with an irresistible need to move the legs. Although the pathogenesis of RLS has not been fully elucidated, it is thought that inflammation also plays a role. Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO can be used as indicators of systemic inflammation. In this study, we aimed to determine the role of inflammation in RLS by measuring the parameters considered as inflammatory indicators in patients with RLS and comparing them with some other parameters. 190 patients with RLS were included in the study. Complete blood count, C-reactive protein, uric acid measurements and Neutrophil-lymphocyte ratio NLR, platelet-lymphocyte ratio PLO, ferritin, erythrocyte sedimentation rate, calcium levels were evaluated and compared. There was a statistically significant and moderate correlation between White Blood Cell-lymphocyte ratio and Neutrophil-lymphocyte ratio NLR. There is a statistically significant and moderate correlation between neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO. Statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO in the group with low iron There is a statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR in the group with low Ca2 r0.548. There is a significant and moderate correlation. In our study, we showed an increase in neutrophil count, decrease in lymphocyte count and increase in Neutrophil-lymphocyte ratio NLR in patients with RLS. Our study supports the role of inflammation in the pathophysiology of RLS.

 Restless Legs Syndrome RLS is a sleep disorder with an irresistible need to move the legs. Although the pathogenesis of RLS has not been fully elucidated, it is thought that inflammation also plays a role. Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO can be used as indicators of systemic inflammation. In this study, we aimed to determine the role of inflammation in RLS by measuring the parameters considered as inflammatory indicators in patients with RLS and comparing them with some other parameters. 190 patients with RLS were included in the study. Complete blood count, C-reactive protein, uric acid measurements and Neutrophil-lymphocyte ratio NLR, platelet-lymphocyte ratio PLO, ferritin, erythrocyte sedimentation rate, calcium levels were evaluated and compared. There was a statistically significant and moderate correlation between White Blood Cell-lymphocyte ratio and Neutrophil-lymphocyte ratio NLR. There is a statistically significant and moderate correlation between neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO. Statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO in the group with low iron There is a statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR in the group with low Ca2 r0.548. There is a significant and moderate correlation. In our study, we showed an increase in neutrophil count, decrease in lymphocyte count and increase in Neutrophil-lymphocyte ratio NLR in patients with RLS. Our study supports the role of inflammation in the pathophysiology of RLS.

 Restless Legs Syndrome RLS is a sleep disorder with an irresistible need to move the legs. Although the pathogenesis of RLS has not been fully elucidated, it is thought that inflammation also plays a role. Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO can be used as indicators of systemic inflammation. In this study, we aimed to determine the role of inflammation in RLS by measuring the parameters considered as inflammatory indicators in patients with RLS and comparing them with some other parameters. 190 patients with RLS were included in the study. Complete blood count, C-reactive protein, uric acid measurements and Neutrophil-lymphocyte ratio NLR, platelet-lymphocyte ratio PLO, ferritin, erythrocyte sedimentation rate, calcium levels were evaluated and compared. There was a statistically significant and moderate correlation between White Blood Cell-lymphocyte ratio and Neutrophil-lymphocyte ratio NLR. There is a statistically significant and moderate correlation between neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO. Statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR and platelet-lymphocyte ratio PLO in the group with low iron There is a statistically significant and moderate correlation between Neutrophil-lymphocyte ratio NLR in the group with low Ca2 r0.548. There is a significant and moderate correlation. In our study, we showed an increase in neutrophil count, decrease in lymphocyte count and increase in Neutrophil-lymphocyte ratio NLR in patients with RLS. Our study supports the role of inflammation in the pathophysiology of RLS.

 Huzursuz Bacaklar sendromu HBS bacaklarda hareket ettirme isteği ihtiyacı olan uyku bozukluğudur. HBS etyolojisi tam olarak aydınlatılamamış olmakla enflamasyonun da rol oynadığını düşünülmektedir. Nötrofil-lenfosit oranı NLO, platelet-lenfosit oranı PLO sistemik enflamasyonun göstergesi açısından kullanılabilmektedir. Biz bu çalışmada HBS tanılı hastalarda enflamatuvar göstergeler olarak kabul edilen parametreleri ölçerek ve diğer bazı parametreler ile kıyaslayarak enflamasyonun HBSdeki rolünü belirlemeyi amaçladık. HBS tanılı 190 hasta çalışmaya dahil edildi. Tam kan sayımı, C-reaktif protein, ürik asit ölçümleri ve Nötrofil-lenfosit oranı NLO, platelet-lenfosit oranı PLO, ferritin, eritrosit sedimantasyon hızı, kalsiyum düzeyleri değerlendirildi ve karşılaştırıldı. White Blood Cell-lenfosit oranı ve Nötrofil-lenfosit oranı NLO arasında istatistiksel anlamlı ve orta düzeyli korelasyon bulunmaktadır. Nötrofil-lenfosit oranı NLO, platelet-lenfosit oranı PLO arasında istatistiksel anlamlı ve orta düzeyli korelasyon bulunmaktadır. Demiri düsük olan grupta Nötrofil-lenfosit oranı NLO, platelet-lenfosit oranı PLO arasında istatistiksel anlamlı ve orta düzeyli korelasyon bulunmaktadır. Ca2 düsük olan grupta Nötrofil-lenfosit oranı NLO arasında istatistiksel anlamlı ve orta düzeyli korelasyon bulunmaktadır r0,548. Ferritin düsük olan grupta Nötrofil-lenfosit oranı NLO, platelet-lenfosit oranı PLO arasında istatistiksel anlamlı ve orta düzeyli korelasyon bulunmaktadır. Bizim çalışmamızda HBS tanılı hastalarda nötrofil sayısında artma, lenfosit sayısında azalma ve Nötrofil-lenfosit oranında NLO artma olduğunu gösterdik. Çalışmamız HBS patofizyolojisinde enflamasyonun rolü olduğunu desteklemektedir.

Makale detayları

Evaluation of Inflation, Neutrophil Lymphocyte and Platelet Lymphocyte Ratios with Other Parameters in Patients with Remarkable Leg Syndrome

Yazarlar:

Hüseyin Duru | Gül Duru | İhsan Asker

Yayıncı:

Karyay Karadeniz Yayımcılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Black Sea Journal of Health Science Vol.6 Issue 2, pp.270-273

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287286

pISSN:

2619-9041

Restless legs syndrome

Ferritin

Calcium

Inflammation

Neutrophil

Lymphocyte

Huzursuz bacaklar sendromu

Ferritin

Kalsiyum

Enflamasyon

Nötrofil

Lenfosit

Sayı

Makale detayları

Yazarlar: Hüseyin Duru | Gül Duru | İhsan Asker

Yayıncı: Karyay Karadeniz Yayımcılık

Ana Başlıklar: İç Hastalıkları

Dergi: Black Sea Journal of Health Science Vol.6 Issue 2, pp.270-273

Belge Tipi: Makale

Yayın Tarihi: 1/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001287286

pISSN: 2619-9041

Sayı

Yazarlar:

Hüseyin Duru | Gül Duru | İhsan Asker

Yayıncı:

Karyay Karadeniz Yayımcılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Black Sea Journal of Health Science Vol.6 Issue 2, pp.270-273

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287286

pISSN:

2619-9041