Antimicrobial Activity of Ethanol and Methanol Extracts of Suillus bovinus (L.) Roussel Mushroom Collected from Selçuk University Campus

Erdoğan Güneş

Makale detayları

Antimicrobial Activity of Ethanol and Methanol Extracts of Suillus bovinus (L.) Roussel Mushroom Collected from Selçuk University Campus

Yazarlar:

Erdoğan Güneş

Yayıncı:

Selcuk University

Ana Başlıklar:

Bacteriology

Dergi:

Selcuk University Journal of Science Faculty Vol.50 Issue 2, pp.60-65

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001327763

pISSN:

2458-9411

Anahtar kelimeler:

Özet:

 The aim of this study is to determine the antimicrobial activity of ethanol and methanol extracts of Suillus bovinus mushroom against some standard pathogenic microorganisms. Broth microdilution method was used to detect antimicrobial activity. It was determined that methanol and ethanol extract of S. bovinus showed activity against gram-positive Staphylococcus aureus and Sarcina lutea and gram-negative Salmonella enteritidis bacteria at a dose of 6.25 mgml. It was detected that both extracts had an antibacterial effect against gram-negative Pseudomonas aeruginosa at a dose of 3.12 mgml. It was determided that both extracts were ineffective against Escherichia coli and Klebsiella pneumoniae bacteria. The strain in which methanol and ethanol extracts showed the highest activity was the gram-positive Bacillus cereus strain, with MIC Minimum Inhibition Concentration values of 0.19 mgml and 0.78 mgml, respectively. Additionally, the study showed that neither extract had an antifungal effect against the Candida albicans yeast strain. As a result, it is thought that the S. bovinus fungus has antibacterial activity and that the antimicrobial compounds obtained from this species with further studies will be a potential source for the development of new drugs and therapeutic agents.

 The aim of this study is to determine the antimicrobial activity of ethanol and methanol extracts of Suillus bovinus mushroom against some standard pathogenic microorganisms. Broth microdilution method was used to detect antimicrobial activity. It was determined that methanol and ethanol extract of S. bovinus showed activity against gram-positive Staphylococcus aureus and Sarcina lutea and gram-negative Salmonella enteritidis bacteria at a dose of 6.25 mgml. It was detected that both extracts had an antibacterial effect against gram-negative Pseudomonas aeruginosa at a dose of 3.12 mgml. It was determided that both extracts were ineffective against Escherichia coli and Klebsiella pneumoniae bacteria. The strain in which methanol and ethanol extracts showed the highest activity was the gram-positive Bacillus cereus strain, with MIC Minimum Inhibition Concentration values of 0.19 mgml and 0.78 mgml, respectively. Additionally, the study showed that neither extract had an antifungal effect against the Candida albicans yeast strain. As a result, it is thought that the S. bovinus fungus has antibacterial activity and that the antimicrobial compounds obtained from this species with further studies will be a potential source for the development of new drugs and therapeutic agents.

 The aim of this study is to determine the antimicrobial activity of ethanol and methanol extracts of Suillus bovinus mushroom against some standard pathogenic microorganisms. Broth microdilution method was used to detect antimicrobial activity. It was determined that methanol and ethanol extract of S. bovinus showed activity against gram-positive Staphylococcus aureus and Sarcina lutea and gram-negative Salmonella enteritidis bacteria at a dose of 6.25 mgml. It was detected that both extracts had an antibacterial effect against gram-negative Pseudomonas aeruginosa at a dose of 3.12 mgml. It was determided that both extracts were ineffective against Escherichia coli and Klebsiella pneumoniae bacteria. The strain in which methanol and ethanol extracts showed the highest activity was the gram-positive Bacillus cereus strain, with MIC Minimum Inhibition Concentration values of 0.19 mgml and 0.78 mgml, respectively. Additionally, the study showed that neither extract had an antifungal effect against the Candida albicans yeast strain. As a result, it is thought that the S. bovinus fungus has antibacterial activity and that the antimicrobial compounds obtained from this species with further studies will be a potential source for the development of new drugs and therapeutic agents.

 Bu çalışmanın amacı Suillus bovinus mantarının etanol ve metanol özütlerinin bazı standart patojen mikoorganizmalara karşı antimikrobiyal aktivitesini belirlemektir. Antimikrobiyal aktiviteyi saptamak için sıvı mikrodilüsyon metodu kullanılmıştır. S. bovinusun metanol ve etanol özütünün, gram pozitif Staphylococcus aureus ve Sarcina lutea, gram negatif Salmonella enteritidis bakterilerine karşı 6.25 mgml dozda antibakteriyel aktivite gösterdiği tespit edilmiştir. Her iki özütün gram negatif Pseudomonas aeruginosaya ise 3.12 mgml dozunda antibakteriyal etki gösterdiği saptanmıştır. Escherichia coli ve Klebsiella pneumoniae bakterilerine karşı her iki özütün de etkisiz olduğu belirlenmiştir. Metanol ve etanol özütü sırasıyla 0.19 mgml ve 0.78 mgml MİK Minimum İnhibisyon Konsantrasyonu değeriyle en yüksek aktivite gösterdikleri suş ise gram pozitif Bacillu cereus suşu olmuştur. Ayrıca yapılan çalışmada Candida albicans maya suşuna karşı her iki özütün antifungal bir etki göstermediği görülmüştür. Sonuç olarak çalışmada, S. bovinus mantarının antibakteriyal aktiviteye sahip olduğu ve ileriki çalışmalarla bu türden elde edilen antimikrobiyal bileşiklerin, yeni ilaçların ve terapötik ajanların geliştirilmesi için potansiyel bir kaynak olacağı düşünülmektedir.

Makale detayları

Antimicrobial Activity of Ethanol and Methanol Extracts of Suillus bovinus (L.) Roussel Mushroom Collected from Selçuk University Campus

Yazarlar:

Erdoğan Güneş

Yayıncı:

Selcuk University

Ana Başlıklar:

Bacteriology

Dergi:

Selcuk University Journal of Science Faculty Vol.50 Issue 2, pp.60-65

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001327763

pISSN:

2458-9411

Antimicrobial activitiy

Broth microdilütion

Mushroom extracts

Suillus bovinusAntimikrobiyal aktivite

Mantar ekstraktları

Sıvı mikrodilüsyon

Suillus bovinus

Sayı

Makale detayları

Yazarlar: Erdoğan Güneş

Yayıncı: Selcuk University

Ana Başlıklar: Bacteriology

Dergi: Selcuk University Journal of Science Faculty Vol.50 Issue 2, pp.60-65

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001327763

pISSN: 2458-9411

Sayı

Yazarlar:

Erdoğan Güneş

Yayıncı:

Selcuk University

Ana Başlıklar:

Bacteriology

Dergi:

Selcuk University Journal of Science Faculty Vol.50 Issue 2, pp.60-65

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001327763

pISSN:

2458-9411