In vitro antioxidant potential of eleven medicinal herbs in Sri Lanka: Correlation with phenols and flavonoids

Ruvini Liyanage

Makale detayları

In vitro antioxidant potential of eleven medicinal herbs in Sri Lanka: Correlation with phenols and flavonoids

Yazarlar:

Ruvini Liyanage

Yayıncı:

İzzet KARA

Ana Başlıklar:

Enzymes

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.630-644

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350185

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 Antioxidants play a crucial role in preventing and treating non-communicable diseases NCDs by scavenging free radicals. Medicinal herbs, used for centuries in traditional healthcare systems, have been gaining attention recently due to the negative effects of synthetic medicines. This study assessed the total phenolic content TPC, total flavonoid content TFC, and antioxidant activity of aqueous extracts from eleven commonly used Sri Lankan Ayurvedic plants and determined the relationship between their phenolic and flavonoid content with antioxidant activities. TPC and TFC were measured using the Folin-Ciocalteu and Aluminum chloride methods, respectively. Antioxidant activity was evaluated using ABTS, FRAP, and DPPH assays. Pearson correlation analysis assessed the relationship between TPC and TFC with antioxidant activity. Phyllanthus emblica PE showed the highest TPC, TFC, and antioxidant activity p0.05 significantly. TPC and TFC exhibited significantly positive correlations with FRAP and ABTS assays while the DPPH assay showed a negative correlation. Phenols and flavonoids in the selected extracts may significantly contribute to the antioxidant activity measured by ABTS and FRAP assays, while other secondary metabolites and their synergism effect may influence the DPPH assay. The significant antioxidant properties of PE, highlight its potential to treat various NCDs. Further studies are essential to determine their bioactivities, effective doses, and toxicity levels.

 Antioxidants play a crucial role in preventing and treating non-communicable diseases NCDs by scavenging free radicals. Medicinal herbs, used for centuries in traditional healthcare systems, have been gaining attention recently due to the negative effects of synthetic medicines. This study assessed the total phenolic content TPC, total flavonoid content TFC, and antioxidant activity of aqueous extracts from eleven commonly used Sri Lankan Ayurvedic plants and determined the relationship between their phenolic and flavonoid content with antioxidant activities. TPC and TFC were measured using the Folin-Ciocalteu and Aluminum chloride methods, respectively. Antioxidant activity was evaluated using ABTS, FRAP, and DPPH assays. Pearson correlation analysis assessed the relationship between TPC and TFC with antioxidant activity. Phyllanthus emblica PE showed the highest TPC, TFC, and antioxidant activity p0.05 significantly. TPC and TFC exhibited significantly positive correlations with FRAP and ABTS assays while the DPPH assay showed a negative correlation. Phenols and flavonoids in the selected extracts may significantly contribute to the antioxidant activity measured by ABTS and FRAP assays, while other secondary metabolites and their synergism effect may influence the DPPH assay. The significant antioxidant properties of PE, highlight its potential to treat various NCDs. Further studies are essential to determine their bioactivities, effective doses, and toxicity levels.

 Antioxidants play a crucial role in preventing and treating non-communicable diseases NCDs by scavenging free radicals. Medicinal herbs, used for centuries in traditional healthcare systems, have been gaining attention recently due to the negative effects of synthetic medicines. This study assessed the total phenolic content TPC, total flavonoid content TFC, and antioxidant activity of aqueous extracts from eleven commonly used Sri Lankan Ayurvedic plants and determined the relationship between their phenolic and flavonoid content with antioxidant activities. TPC and TFC were measured using the Folin-Ciocalteu and Aluminum chloride methods, respectively. Antioxidant activity was evaluated using ABTS, FRAP, and DPPH assays. Pearson correlation analysis assessed the relationship between TPC and TFC with antioxidant activity. Phyllanthus emblica PE showed the highest TPC, TFC, and antioxidant activity p0.05 significantly. TPC and TFC exhibited significantly positive correlations with FRAP and ABTS assays while the DPPH assay showed a negative correlation. Phenols and flavonoids in the selected extracts may significantly contribute to the antioxidant activity measured by ABTS and FRAP assays, while other secondary metabolites and their synergism effect may influence the DPPH assay. The significant antioxidant properties of PE, highlight its potential to treat various NCDs. Further studies are essential to determine their bioactivities, effective doses, and toxicity levels.

 Antioxidants play a crucial role in preventing and treating non-communicable diseases NCDs by scavenging free radicals. Medicinal herbs, used for centuries in traditional healthcare systems, have been gaining attention recently due to the negative effects of synthetic medicines. This study assessed the total phenolic content TPC, total flavonoid content TFC, and antioxidant activity of aqueous extracts from eleven commonly used Sri Lankan Ayurvedic plants and determined the relationship between their phenolic and flavonoid content with antioxidant activities. TPC and TFC were measured using the Folin-Ciocalteu and Aluminum chloride methods, respectively. Antioxidant activity was evaluated using ABTS, FRAP, and DPPH assays. Pearson correlation analysis assessed the relationship between TPC and TFC with antioxidant activity. Phyllanthus emblica PE showed the highest TPC, TFC, and antioxidant activity p0.05 significantly. TPC and TFC exhibited significantly positive correlations with FRAP and ABTS assays while the DPPH assay showed a negative correlation. Phenols and flavonoids in the selected extracts may significantly contribute to the antioxidant activity measured by ABTS and FRAP assays, while other secondary metabolites and their synergism effect may influence the DPPH assay. The significant antioxidant properties of PE, highlight its potential to treat various NCDs. Further studies are essential to determine their bioactivities, effective doses, and toxicity levels.

Makale detayları

In vitro antioxidant potential of eleven medicinal herbs in Sri Lanka: Correlation with phenols and flavonoids

Yazarlar:

Ruvini Liyanage

Yayıncı:

İzzet KARA

Ana Başlıklar:

Enzymes

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.630-644

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350185

pISSN:

2148-6905

Medicinal plants

Antioxidant activity

Total phenolic content

Total flavonoid contentMedicinal plants

Antioxidant activity

Total phenolic content

Total flavonoid content

Sayı

Makale detayları

Yazarlar: Ruvini Liyanage

Yayıncı: İzzet KARA

Ana Başlıklar: Enzymes

Dergi: International Journal of Secondary Metabolite Vol.12 Issue 3, pp.630-644

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001350185

pISSN: 2148-6905

Sayı

Yazarlar:

Ruvini Liyanage

Yayıncı:

İzzet KARA

Ana Başlıklar:

Enzymes

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.630-644

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350185

pISSN:

2148-6905