Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Haci Hasan YETER; Tolga YILDIRIM; Nesrin Damla EYÜPOĞLU; Tural PASAYEV; Abdullah Tarik ASLAN; Sila ÇETİK; Ömer Faruk AKÇAY; Arzu Topeli İSKİT; Mustafa ARICI

Makale detayları

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Yazarlar:

Haci Hasan YETER | Tolga YILDIRIM | Nesrin Damla EYÜPOĞLU | Tural PASAYEV | Abdullah Tarik ASLAN | Sila ÇETİK | Ömer Faruk AKÇAY | Arzu Topeli İSKİT | Mustafa ARICI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.543-550

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000750188

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Lack of early predictors of acute kidney injury is currently delaying timely diagnosis.This study was done to evaluate the relationship between mild to moderate proteinuria and incidence of acute kidney injury (AKI) and 28-day mortality in intensive care unit (ICU) patients. Material and methods: This observational, retrospective study was conducted in the internal medicine ICU. A total of 796 patients were screened and 525 patients were used for this analysis. Proteinuria was measured by urine dipstick test. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Results: Patients with dipstick urine protein positivity on admission had higher proportion of AKI and 28-day mortality compared to dipstick urine protein negative group [164 (59.6%) vs. 111 (44.4%) and 101 (36.7%) vs. 54 (21.6%), P = 0.01 and P  60 mL/min (hazard ratio: 1.988, 95% confidence interval 1.380-2.862). Conclusion: Proteinuria before ICU admission is a risk factor for development of AKI within seven days of ICU stay and also is a risk factor for 28-day mortality, even in patients with GFR > 60 mL/min.

Makale detayları

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Yazarlar: Haci Hasan YETER | Tolga YILDIRIM | Nesrin Damla EYÜPOĞLU | Tural PASAYEV | Abdullah Tarik ASLAN | Sila ÇETİK | Ömer Faruk AKÇAY | Arzu Topeli İSKİT | Mustafa ARICI

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.543-550

Belge Tipi: Makale

Yayın Tarihi: 3/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000750188

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Haci Hasan YETER | Tolga YILDIRIM | Nesrin Damla EYÜPOĞLU | Tural PASAYEV | Abdullah Tarik ASLAN | Sila ÇETİK | Ömer Faruk AKÇAY | Arzu Topeli İSKİT | Mustafa ARICI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.543-550

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000750188

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144