Fabrication and Characterization of Montmorillonite Doped Polymeric Composite Films Modified with Silane Agents

Şükran Melda Eskitoros Toğay; Aleyna Yeşilyurt; Sema Çörtoğlu

Makale detayları

Fabrication and Characterization of Montmorillonite Doped Polymeric Composite Films Modified with Silane Agents

Yazarlar:

Şükran Melda Eskitoros Toğay | Aleyna Yeşilyurt | Sema Çörtoğlu

Yayıncı:

Fırat University

Ana Başlıklar:

Malzeme Bilimi ve Teknolojileri | Polimer Bilimi ve Teknolojileri | Nanoteknoloji (Diğer)

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 2, pp.695-704

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317071

pISSN:

1308-9072

Anahtar kelimeler:

Özet:

 In this study, montmorillonite MMT, used as filler, was modified with two different silane agents 3- aminopropyltriethoxysilane APTES and 3-glycidoxypropyltrimethoxysilane GPTMS to increase the interfacial interaction with the organic phase and ensure homogeneous distribution in the polymer matrix. As polymer matrix, polycaprolactone PCL, a synthetic polymer with biodegradable and biocompatible properties, and polyvinylpyrrolidone PVP, a biocompatible and hydrophilic polymer, were used together and biomaterials were produced by solution casting method. The morphological, physicochemical and mechanical properties of the biomaterials proposed for use as scaffolds for bone tissue engineering were characterized by atomic force microscopy AFM, Fourier transform infrared spectroscopy FT-IR, X-ray diffractometry XRD, contact angle analysis, water absorption capacity analysis and mechanical analysis. AFM results showed that the roughness of the PCLPVP polymer matrix decreased from 0.507 µm to 0.171 µm with the addition of unmodified MMT and to 0.160 µm with the addition of MMT-APTES. The highest roughness ratio was found to be 0.530 µm in GPTMS-modified MMT doped biomaterials. When contact angle values and water absorption capacities were compared, it was observed that APTES and GPTMS-modified MMT doped biomaterials with contact angles of 68.4 and 59.7 were more hydrophilic than the biomaterial without MMT and the water absorption capacity was 125 and 144 higher than the polymer matrix without MMT and the unmodified biomaterial. In conclusion, this preliminary study suggests that APTES-modified MMT doped PCLPVP biomaterials can be used as tissue scaffolds in the treatment of bone tissue damage.

 In this study, montmorillonite MMT, used as filler, was modified with two different silane agents 3- aminopropyltriethoxysilane APTES and 3-glycidoxypropyltrimethoxysilane GPTMS to increase the interfacial interaction with the organic phase and ensure homogeneous distribution in the polymer matrix. As polymer matrix, polycaprolactone PCL, a synthetic polymer with biodegradable and biocompatible properties, and polyvinylpyrrolidone PVP, a biocompatible and hydrophilic polymer, were used together and biomaterials were produced by solution casting method. The morphological, physicochemical and mechanical properties of the biomaterials proposed for use as scaffolds for bone tissue engineering were characterized by atomic force microscopy AFM, Fourier transform infrared spectroscopy FT-IR, X-ray diffractometry XRD, contact angle analysis, water absorption capacity analysis and mechanical analysis. AFM results showed that the roughness of the PCLPVP polymer matrix decreased from 0.507 µm to 0.171 µm with the addition of unmodified MMT and to 0.160 µm with the addition of MMT-APTES. The highest roughness ratio was found to be 0.530 µm in GPTMS-modified MMT doped biomaterials. When contact angle values and water absorption capacities were compared, it was observed that APTES and GPTMS-modified MMT doped biomaterials with contact angles of 68.4 and 59.7 were more hydrophilic than the biomaterial without MMT and the water absorption capacity was 125 and 144 higher than the polymer matrix without MMT and the unmodified biomaterial. In conclusion, this preliminary study suggests that APTES-modified MMT doped PCLPVP biomaterials can be used as tissue scaffolds in the treatment of bone tissue damage.

 In this study, montmorillonite MMT, used as filler, was modified with two different silane agents 3- aminopropyltriethoxysilane APTES and 3-glycidoxypropyltrimethoxysilane GPTMS to increase the interfacial interaction with the organic phase and ensure homogeneous distribution in the polymer matrix. As polymer matrix, polycaprolactone PCL, a synthetic polymer with biodegradable and biocompatible properties, and polyvinylpyrrolidone PVP, a biocompatible and hydrophilic polymer, were used together and biomaterials were produced by solution casting method. The morphological, physicochemical and mechanical properties of the biomaterials proposed for use as scaffolds for bone tissue engineering were characterized by atomic force microscopy AFM, Fourier transform infrared spectroscopy FT-IR, X-ray diffractometry XRD, contact angle analysis, water absorption capacity analysis and mechanical analysis. AFM results showed that the roughness of the PCLPVP polymer matrix decreased from 0.507 µm to 0.171 µm with the addition of unmodified MMT and to 0.160 µm with the addition of MMT-APTES. The highest roughness ratio was found to be 0.530 µm in GPTMS-modified MMT doped biomaterials. When contact angle values and water absorption capacities were compared, it was observed that APTES and GPTMS-modified MMT doped biomaterials with contact angles of 68.4 and 59.7 were more hydrophilic than the biomaterial without MMT and the water absorption capacity was 125 and 144 higher than the polymer matrix without MMT and the unmodified biomaterial. In conclusion, this preliminary study suggests that APTES-modified MMT doped PCLPVP biomaterials can be used as tissue scaffolds in the treatment of bone tissue damage.

 Bu çalışmada, dolgu maddesi olarak kullanılan montmorillonit MMT, iki farklı silan ajanı 3- aminopropiltrietoksisilan APTES ve 3-glisidoksipropiltrimetoksisilan GPTMS ile modifiye edilmiş, organik faz ile ara yüzey etkileşiminin arttırılması ve polimer matrisi içerisinde homojen bir şekilde dağılması sağlanmıştır. Polimer matris olarak ise biyobozunur ve biyouyumlu özelliklere sahip sentetik polimerlerden polikaprolakton PCL ve biyouyumlu ve hidrofilik özelliğe sahip polivinilpirolidon PVP birlikte kullanılmış ve çözelti döküm yöntemiyle biyomalzemeler üretilmiştir. Kemik doku mühendisliğine yönelik doku iskelesi olarak kullanımı ön görülen biyomalzemelerin morfolojik, fizikokimyasal ve mekanik özellikleri, atomik kuvvet mikroskobu AFM, Fourier transform kızılötesi spektroskopisi FT-IR, X-ışını difraktometresi XRD, temas açısı analizi, su absorplama kapasitesi analizi ve mekanik analiz ile karakterize edilmiştir. AFM sonuçları, PCLPVP polimer matrisinin 0,507 µm olan pürüzlülük değerinin modifiye edilmemiş MMTnin eklenmesiyle 0,171 µm ve MMT-APTES eklenmesiyle ise 0,160 µm değerine düştüğünü göstermiştir. Pürüzlülük oranı en yüksek GPTMS ile modifiye edilmiş MMT katkılı biyomalzemelerde 0,530 µm olarak bulunmuştur. Temas açı değerleri ve su absorplama kapasiteleri karşılaştırıldığında, 68,4 ve 59,7 temas açı değerleri bulunan APTES ve GPTMS ile modifiye edilmiş MMT katkılı biyomalzemelerin, MMT katılmamış biyomalzemeden daha hidrofilik olduğu ve su absorplama kapasitesinin MMT katılmamış polimer matristen ve modifiye edilmemiş biyomalzemeden 125 ve 144 olarak daha yüksek olduğu görülmüştür. Sonuç olarak, ön değerlendirme niteliğindeki bu çalışmamız ile APTES ile modifiye edilmiş MMT katkılı PCLPVP biyomalzemelerinin kemik doku hasarlarının tedavisinde doku iskelesi olarak kullanılabileceği ön görülmektedir.

Makale detayları

Fabrication and Characterization of Montmorillonite Doped Polymeric Composite Films Modified with Silane Agents

Yazarlar:

Şükran Melda Eskitoros Toğay | Aleyna Yeşilyurt | Sema Çörtoğlu

Yayıncı:

Fırat University

Ana Başlıklar:

Malzeme Bilimi ve Teknolojileri | Polimer Bilimi ve Teknolojileri | Nanoteknoloji (Diğer)

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 2, pp.695-704

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317071

pISSN:

1308-9072

Montmorillonite

silane

polycaprolactone

polyvinylpyrrolidone

tissue scaffold.Montmorillonit

silan

polikaprolakton

polivinilpirolidon

doku iskelesi

Sayı

Makale detayları

Yazarlar: Şükran Melda Eskitoros Toğay | Aleyna Yeşilyurt | Sema Çörtoğlu

Yayıncı: Fırat University

Ana Başlıklar: Malzeme Bilimi ve Teknolojileri | Polimer Bilimi ve Teknolojileri | Nanoteknoloji (Diğer)

Dergi: Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 2, pp.695-704

Belge Tipi: Makale

Yayın Tarihi: 9/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001317071

pISSN: 1308-9072

Sayı

Yazarlar:

Şükran Melda Eskitoros Toğay | Aleyna Yeşilyurt | Sema Çörtoğlu

Yayıncı:

Fırat University

Ana Başlıklar:

Malzeme Bilimi ve Teknolojileri | Polimer Bilimi ve Teknolojileri | Nanoteknoloji (Diğer)

Dergi:

Fırat Üniversitesi Mühendislik Bilimleri Dergisi Vol.36 Issue 2, pp.695-704

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001317071

pISSN:

1308-9072