The Effect of Peripheral Adropin Application  on Hypothalamic Pituitary Adrenal Axis   in Rats

Mustafa Can GÜLER; Tuncer NACAR; Ersen ERASLAN; Ayhan TANYELİ; Elif POLAT; Selim ÇOMAKLI

Makale detayları

The Effect of Peripheral Adropin Application on Hypothalamic Pituitary Adrenal Axis in Rats

Yazarlar:

Mustafa Can GÜLER | Tuncer NACAR | Ersen ERASLAN | Ayhan TANYELİ | Elif POLAT | Selim ÇOMAKLI

Yayıncı:

Ahmet Ocak AKDEMİR

Dergi:

Turkish Journal of Science 2019 Vol.4 Issue 2, pp.60-75

Belge Tipi:

Makale

Yayın Tarihi:

10/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000639049

Sıklık:

Üç Yıllık

eISSN:

2587-0971

pISSN:

2587-0971

Özet:

 


Purpose:Hypothalamic pituitary adrenal (HPA) axis has many missions such as responses to stress and inflammatory factors. HPA axis is the primer stress response system. Adropin is a peptid structured hormone coded by energy homeostasis related gene. In this study biochemical, histopathologic and immunohistochemical effects of adropin hormone on HPA axis were examined.



Findings:While cortisole, adrenaline, noradrenaline and serotonin levels decreased, contrary dopamin levels increased. There were no important changes on melatonin levels. As a consequence of immunohistochemical staining, CRH has shown increase in adropin groups compared to other groups.


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Makale detayları

The Effect of Peripheral Adropin Application on Hypothalamic Pituitary Adrenal Axis in Rats

Yazarlar: Mustafa Can GÜLER | Tuncer NACAR | Ersen ERASLAN | Ayhan TANYELİ | Elif POLAT | Selim ÇOMAKLI

Yayıncı: Ahmet Ocak AKDEMİR

Dergi: Turkish Journal of Science 2019 Vol.4 Issue 2, pp.60-75

Belge Tipi: Makale

Yayın Tarihi: 10/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000639049

Sıklık: Üç Yıllık

eISSN: 2587-0971

pISSN: 2587-0971

Sayı

Yazarlar:

Mustafa Can GÜLER | Tuncer NACAR | Ersen ERASLAN | Ayhan TANYELİ | Elif POLAT | Selim ÇOMAKLI

Yayıncı:

Ahmet Ocak AKDEMİR

Dergi:

Turkish Journal of Science 2019 Vol.4 Issue 2, pp.60-75

Belge Tipi:

Makale

Yayın Tarihi:

10/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000639049

Sıklık:

Üç Yıllık

eISSN:

2587-0971

pISSN:

2587-0971