Molecular Investigation of Metallo-β-lactamase Encoding Gene in Nosocomial Carbapenem-Resistant Enterobacteriaceae in Iraqi Hospitals

Ahmed S. K. AL-KHAFAJI; Shaymaa Fadhel Abbas ALBAAYIT; Omyma S. IBRAHEEM; Hawraa H. ABDUL-ILAH

Makale detayları

Molecular Investigation of Metallo-β-lactamase Encoding Gene in Nosocomial Carbapenem-Resistant Enterobacteriaceae in Iraqi Hospitals

Yazarlar:

Ahmed S. K. AL-KHAFAJI | Shaymaa Fadhel Abbas ALBAAYIT | Omyma S. IBRAHEEM | Hawraa H. ABDUL-ILAH

Ana Başlıklar:

Uygulamalı fizik

Dergi:

The Eurasia Proceedings of Science Technology Engineering and Mathematics 2018 Issue 2, pp.239-243

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000661189

Özet:

 


In recent years, there has been an increasing
amount of evidence that nosocomial carbapenem-resistant Enterobacteriaceae pose
a major puplic health threat. This study aims to uncover the association of
multidrug-resistance related genes with increasing the rate of acquired
hospital infections by Enterobacteriaceae pathogens. Enterobacteriaceae species
(n=57) were detected in clinical specimens (n=45) obtained from patients with
infected wounds and burns in 3 Iraqi hospitals. Carbapenem-resistant
Enterobacteriaceae bacteria were investigated by antibacterial susceptibility tests.  The Molecular investigation by PCR analysis
showed that Klebsiella
pneumonia isolates
(n=5) and Escherichia coli isolates (n=3) are carrying
metallo-β-lactamase encoding gene (blaIMP).
It can be concluded that the expression of blaIMP is considered among the main
reasons of dominating resistance strains of Enterobacteriaceae pathogens and
thus spreading nosocomial infection in Iraqi clinical centers. However, further
molecular investigation is needed to overcome this resistance on molecular
bases when treating.

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Makale detayları

Molecular Investigation of Metallo-β-lactamase Encoding Gene in Nosocomial Carbapenem-Resistant Enterobacteriaceae in Iraqi Hospitals

Yazarlar: Ahmed S. K. AL-KHAFAJI | Shaymaa Fadhel Abbas ALBAAYIT | Omyma S. IBRAHEEM | Hawraa H. ABDUL-ILAH

Ana Başlıklar: Uygulamalı fizik

Dergi: The Eurasia Proceedings of Science Technology Engineering and Mathematics 2018 Issue 2, pp.239-243

Belge Tipi: Makale

Yayın Tarihi: 8/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000661189

Sayı

Yazarlar:

Ahmed S. K. AL-KHAFAJI | Shaymaa Fadhel Abbas ALBAAYIT | Omyma S. IBRAHEEM | Hawraa H. ABDUL-ILAH

Ana Başlıklar:

Uygulamalı fizik

Dergi:

The Eurasia Proceedings of Science Technology Engineering and Mathematics 2018 Issue 2, pp.239-243

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000661189