Deneysel Florozis Oluşturulmuş Ratlarda Tedavi ve Koruma Amaçlı Vitamin C ve Vitamin E Uygulamasının Serum Vitamin Düzeyleri Üzerine Etkisi

Ahmet Cihat ÖNER; Sedat ÇETİN; İbrahim YÖRÜK; Semiha DEDE

Makale detayları

Deneysel Florozis Oluşturulmuş Ratlarda Tedavi ve Koruma Amaçlı Vitamin C ve Vitamin E Uygulamasının Serum Vitamin Düzeyleri Üzerine Etkisi

Yazarlar:

Ahmet Cihat ÖNER | Sedat ÇETİN | İbrahim YÖRÜK | Semiha DEDE

Yayıncı:

Ataturk University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Atatürk University Journal of Veterinary Sciences 2021 Vol.16 Issue 2, pp.211-218

Belge Tipi:

Makale

Yayın Tarihi:

10/2021

Belge Dili:

Türkçe

Document ID (Org No.):

2000686075

Sıklık:

Aylık

eISSN:

2822-3608

Özet:

 

This study aimed to determine the vitamins A-D and E levels in rats with experimental fluorosis and in whom vitamins, C and E were administered for prevention and treatment. One-month-old Wistar-Albino rats were used as material in the study. Nine groups of 8 animals each were studied. Sodium fluoride (NaF) solutions (150 mg / kg) prepared in drinking water were administered ad-libitum during the study. Vitamin C (100 mg / kg), Vitamin E (300 mg / kg) and Vitamin C + Vitamin E (100 mg / kg + 300 mg / kg) were administered to the protection group with water containing 150 ppm NaF for 16 weeks / day. Water containing 150 ppm NaF was given ad-libitum for 16 weeks in the treatment group, and then Vitamin C (100 mg/kg), Vitamin E (300 mg/kg) and Vitamin C + Vitamin E (100 mg/kg + 300 mg/kg) were administered along with normal drinking water for 4 weeks. At the end of sixteen weeks, blood samples were taken from the rats and their serums were removed. Serum Retinol, α-Tocopherol, Vitamin D3 levels were determined by HPLC. In the fluorosis group, it was found that there was no change in serum vitamin A and vitamin D levels with the application of vitamins C and E for treatment and protection, but a decrease in vitamin E level. As a result, it was concluded that the administration of vitamin E is effective in both the prevention and treatment of fluorosis cases.

Makale detayları

Deneysel Florozis Oluşturulmuş Ratlarda Tedavi ve Koruma Amaçlı Vitamin C ve Vitamin E Uygulamasının Serum Vitamin Düzeyleri Üzerine Etkisi

Yazarlar: Ahmet Cihat ÖNER | Sedat ÇETİN | İbrahim YÖRÜK | Semiha DEDE

Yayıncı: Ataturk University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Atatürk University Journal of Veterinary Sciences 2021 Vol.16 Issue 2, pp.211-218

Belge Tipi: Makale

Yayın Tarihi: 10/2021

Belge Dili: Türkçe

Document ID (Org No.): 2000686075

Sıklık: Aylık

eISSN: 2822-3608

Sayı

Yazarlar:

Ahmet Cihat ÖNER | Sedat ÇETİN | İbrahim YÖRÜK | Semiha DEDE

Yayıncı:

Ataturk University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Atatürk University Journal of Veterinary Sciences 2021 Vol.16 Issue 2, pp.211-218

Belge Tipi:

Makale

Yayın Tarihi:

10/2021

Belge Dili:

Türkçe

Document ID (Org No.):

2000686075

Sıklık:

Aylık

eISSN:

2822-3608