Does recipient weight and surgical approach really matter in pediatric renal transplantation?

Eryigit Eren; Ayhan Dinçkan

Makale detayları

Does recipient weight and surgical approach really matter in pediatric renal transplantation?

Yazarlar:

Eryigit Eren | Ayhan Dinçkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.494-499

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286267

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aim: To compare the outcomes between low-weight 15 kg and normal-weight 15 kg children who underwent renal transplantation RT and investigate the impact of the surgical approach intraperitoneal or extraperitoneal RT. Material and Method: This study was designed as an observational single-centre study and was conducted in Istinye University Hospital, Istanbul, Turkey, between January 2018 and June 2021. Data including age, gender, weight, surgical approach intraperitonealextraperitoneal, complications, length of hospital stay, graft and patient survival were collected. Low-weight LW and normal-weight NW patients were compared. A p value less than 0.05 was considered statistically significant. Results: Overall, 107 33 LW and 74 NW patients aged between 1 and 17 were included. The LW group had a significantly lower age and a significantly longer duration of intensive care unit ICU, and inpatient floor stays than the NW group p0.001. Intraperitoneal RT IRT was significantly more common in the LW group 57.6 vs 42.4, while ERT was more frequent in the NW group 87.8 vs 12.2 p0.001. Both early complication and mortality rates were significantly higher in the LW group than in the NW group p0.001 and p0.031. A comparison between the LW and NW patients who underwent ERT revealed that the mean patient age was significantly lower, while the duration of ICU stay was higher in the former than in the latter group p0.001 and p0.004. However, the length of inpatient floor stay, early-term complication, and mortality rates were similar p0.05. Conclusion: The extraperitoneal approach should be encouraged in children weighing less than 15 kg.

 Aim: To compare the outcomes between low-weight 15 kg and normal-weight 15 kg children who underwent renal transplantation RT and investigate the impact of the surgical approach intraperitoneal or extraperitoneal RT. Material and Method: This study was designed as an observational single-centre study and was conducted in Istinye University Hospital, Istanbul, Turkey, between January 2018 and June 2021. Data including age, gender, weight, surgical approach intraperitonealextraperitoneal, complications, length of hospital stay, graft and patient survival were collected. Low-weight LW and normal-weight NW patients were compared. A p value less than 0.05 was considered statistically significant. Results: Overall, 107 33 LW and 74 NW patients aged between 1 and 17 were included. The LW group had a significantly lower age and a significantly longer duration of intensive care unit ICU, and inpatient floor stays than the NW group p0.001. Intraperitoneal RT IRT was significantly more common in the LW group 57.6 vs 42.4, while ERT was more frequent in the NW group 87.8 vs 12.2 p0.001. Both early complication and mortality rates were significantly higher in the LW group than in the NW group p0.001 and p0.031. A comparison between the LW and NW patients who underwent ERT revealed that the mean patient age was significantly lower, while the duration of ICU stay was higher in the former than in the latter group p0.001 and p0.004. However, the length of inpatient floor stay, early-term complication, and mortality rates were similar p0.05. Conclusion: The extraperitoneal approach should be encouraged in children weighing less than 15 kg.

 Aim: To compare the outcomes between low-weight 15 kg and normal-weight 15 kg children who underwent renal transplantation RT and investigate the impact of the surgical approach intraperitoneal or extraperitoneal RT. Material and Method: This study was designed as an observational single-centre study and was conducted in Istinye University Hospital, Istanbul, Turkey, between January 2018 and June 2021. Data including age, gender, weight, surgical approach intraperitonealextraperitoneal, complications, length of hospital stay, graft and patient survival were collected. Low-weight LW and normal-weight NW patients were compared. A p value less than 0.05 was considered statistically significant. Results: Overall, 107 33 LW and 74 NW patients aged between 1 and 17 were included. The LW group had a significantly lower age and a significantly longer duration of intensive care unit ICU, and inpatient floor stays than the NW group p0.001. Intraperitoneal RT IRT was significantly more common in the LW group 57.6 vs 42.4, while ERT was more frequent in the NW group 87.8 vs 12.2 p0.001. Both early complication and mortality rates were significantly higher in the LW group than in the NW group p0.001 and p0.031. A comparison between the LW and NW patients who underwent ERT revealed that the mean patient age was significantly lower, while the duration of ICU stay was higher in the former than in the latter group p0.001 and p0.004. However, the length of inpatient floor stay, early-term complication, and mortality rates were similar p0.05. Conclusion: The extraperitoneal approach should be encouraged in children weighing less than 15 kg.

 Amaç: Renal transplantasyon RT uygulanan düşük ağırlıklı 15 kg ve normal ağırlıklı 15 kg çocuklar arasındaki sonuçları karşılaştırmak ve cerrahi yaklaşımın intraperitoneal veya ekstraperitoneal RT etkisini araştırmak. Gereç ve Yöntem: Bu çalışma gözlemsel tek merkezli bir çalışma olarak tasarlandı ve Ocak 2018 ile Haziran 2021 tarihleri arasında İstinye Üniversitesi Hastanesi, İstanbul, Türkiyede gerçekleştirildi. Yaş, cinsiyet, kilo, cerrahi yaklaşım intraperitonealextraperitoneal, komplikasyonlar, hastanede kalış süresi, greft ve hasta sağkalımı toplandı. Düşük kilolu DK ve normal kilolu NK hastalar karşılaştırıldı. 0.05ten küçük bir p değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: 1 ile 17 yaşları arasında 107 33 DK ve 74 NK hasta dahil edildi. DK grubu, NK grubuna göre anlamlı olarak daha düşük bir yaşa ve anlamlı olarak daha uzun yoğun bakım ünitesi YBÜ ve hastane yatış süresine sahipti p0.001. İntraperitoneal RT IRT DK grubunda anlamlı olarak daha fazlaydı 57,6ya karşı 42,4, ERT ise NK grubunda 87,8e karşı 12,2 daha sıktı p0.001 . Hem erken komplikasyon hem de ölüm oranları DK grubunda NK grubuna göre anlamlı olarak yüksekti p0.001 ve p0.031. ERT uygulanan DK ve NK hastalarının karşılaştırılması, ortalama hasta yaşının anlamlı olarak daha düşük olduğunu, yoğun bakımda kalış süresinin ise ikinci gruba göre daha yüksek olduğunu gösterdi p0.001 ve p0.004. Ancak hastanede yatış süresi, erken dönem komplikasyon ve mortalite oranları benzerdi p0,05. Sonuç: 15 kgın altındaki çocuklarda ekstraperitoneal yaklaşım teşvik edilmelidir.

Makale detayları

Does recipient weight and surgical approach really matter in pediatric renal transplantation?

Yazarlar:

Eryigit Eren | Ayhan Dinçkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.494-499

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286267

pISSN:

2636-8579

Renal transplantation

Pediatric

Low-weight

Intraperitoneal

Extraperitoneal

Böbrek nakli

Pediatrik

Düşük kilo

İntraperitoneal

Ekstraperitoneal

Sayı

Makale detayları

Yazarlar: Eryigit Eren | Ayhan Dinçkan

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.494-499

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286267

pISSN: 2636-8579

Sayı

Yazarlar:

Eryigit Eren | Ayhan Dinçkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.494-499

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286267

pISSN:

2636-8579