Diterpenes from Sideritis sipylea and S. dichotoma

Gülaçtı TOPÇU*; Ahmet C. GÖREN

Makale detayları

Diterpenes from Sideritis sipylea and S. dichotoma

Yazarlar:

Gülaçtı TOPÇU* | Ahmet C. GÖREN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2002 Vol.26 Issue 2, pp.189-194

Belge Tipi:

Makale

Yayın Tarihi:

1/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000729940

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Two Sideritis species afforded eleven kaurene and one  beyerene diterpenes.  Structures of the compounds from  Sideritis sipylea} were elucidated as linearol (1),  7-epicandicandiol (2), sideridiol (3), siderol  (4), isolinearol (5), isosidol (6) and  epoxyisolinearol (7).  Linearol was treated with   m -chloroperbenzoic to afford its analogues ent-3b  ,7a ,17-trihydroxy-18-acetoxykaur-15-ene (1a) and  ent}-7a ,17,18-trihydroxy-3b -acetoxykaur-15-ene  (1b) as new compounds.  From the second species,  Sideritis dichotoma, the kaurenes sideridiol (3)   siderol (4), ent-7a ,18-dihydroxy-15b  ,16b -epoxykaurane (8)}, ent}-7a  -acetoxy,18-hydroxy-15b ,16b -epoxykaurane  (9), ent-7a  -acetoxy-15,18-dihydroxy-kaur-16-ene (10),  ent-7a ,15,18-trihydroxykaur-16-ene (11) and  the beyerene ent-7a ,18-dihydroxybeyer-15-ene  (12) were isolated.  Structural elucidation is based on NMR  techniques and mass spectrometer analyses.

 

Two Sideritis species afforded eleven kaurene and one  beyerene diterpenes.  Structures of the compounds from  Sideritis sipylea} were elucidated as linearol (1),  7-epicandicandiol (2), sideridiol (3), siderol  (4), isolinearol (5), isosidol (6) and  epoxyisolinearol (7).  Linearol was treated with   m -chloroperbenzoic to afford its analogues ent-3b  ,7a ,17-trihydroxy-18-acetoxykaur-15-ene (1a) and  ent}-7a ,17,18-trihydroxy-3b -acetoxykaur-15-ene  (1b) as new compounds.  From the second species,  Sideritis dichotoma, the kaurenes sideridiol (3)   siderol (4), ent-7a ,18-dihydroxy-15b  ,16b -epoxykaurane (8)}, ent}-7a  -acetoxy,18-hydroxy-15b ,16b -epoxykaurane  (9), ent-7a  -acetoxy-15,18-dihydroxy-kaur-16-ene (10),  ent-7a ,15,18-trihydroxykaur-16-ene (11) and  the beyerene ent-7a ,18-dihydroxybeyer-15-ene  (12) were isolated.  Structural elucidation is based on NMR  techniques and mass spectrometer analyses.

Makale detayları

Diterpenes from Sideritis sipylea and S. dichotoma

Yazarlar: Gülaçtı TOPÇU* | Ahmet C. GÖREN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2002 Vol.26 Issue 2, pp.189-194

Belge Tipi: Makale

Yayın Tarihi: 1/2002

Belge Dili: Türkçe

Document ID (Org No.): 2000729940

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Gülaçtı TOPÇU* | Ahmet C. GÖREN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2002 Vol.26 Issue 2, pp.189-194

Belge Tipi:

Makale

Yayın Tarihi:

1/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000729940

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527