The diagnostik value of eosinophil-to-lymphocyte ratio in predicting contrast-induced nephropathy in patients with ST-segment elevation myocardial infarction

Orhan Karayiğit; Murat Gök; Ahmet Balun; Alparslan Kurtul

Makale detayları

The diagnostik value of eosinophil-to-lymphocyte ratio in predicting contrast-induced nephropathy in patients with ST-segment elevation myocardial infarction

Yazarlar:

Orhan Karayiğit | Murat Gök | Ahmet Balun | Alparslan Kurtul

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.120-125

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343176

pISSN:

2718-0115

Anahtar kelimeler:

Özet:

 Aims: Inflammation is considered a major contributor to the development of contrast-induced nephropathy CIN. The purpose of this study was to assess the effectiveness of eosinophil-to-lymphocyte ratio ELR as a predictor of CIN among patients who experienced percutaneous coronary intervention PCI for ST-segment elevation myocardial infarction STEMI. Methods: The study involved 440 patients diagnosed with STEMI who underwent primary PCI. The participants were categorized into two classes based on whether they had CIN or not. ELR was calculated by dividing the eosinophil count by the lymphocyte count. Results: The group with CIN  showed significantly higher ELR levels 0.1340.063 vs. 0.0690.037, p0.001. According to the ROC curve assessment, the best threshold level of ELR to predict CIN development was identified as 0.093, with 75.9 sensitivity and 79.1 specificity AUC: 0.836; 95 CI: 0.7830.889; p0.001. Logistic regression analysis revealed that estimated glomerular filtration rate eGFR, C-reactive protein, left ventricular ejection fraction, and ELR were independent predictors of CIN. Conclusion: ELR could be an effective and reliable marker to predict CIN development in individuals with STEMI who undergo primary PCI. Early prediction of CIN risk is critical to provide intensive preventive measures for high-risk patients.

 Aims: Inflammation is considered a major contributor to the development of contrast-induced nephropathy CIN. The purpose of this study was to assess the effectiveness of eosinophil-to-lymphocyte ratio ELR as a predictor of CIN among patients who experienced percutaneous coronary intervention PCI for ST-segment elevation myocardial infarction STEMI. Methods: The study involved 440 patients diagnosed with STEMI who underwent primary PCI. The participants were categorized into two classes based on whether they had CIN or not. ELR was calculated by dividing the eosinophil count by the lymphocyte count. Results: The group with CIN  showed significantly higher ELR levels 0.1340.063 vs. 0.0690.037, p0.001. According to the ROC curve assessment, the best threshold level of ELR to predict CIN development was identified as 0.093, with 75.9 sensitivity and 79.1 specificity AUC: 0.836; 95 CI: 0.7830.889; p0.001. Logistic regression analysis revealed that estimated glomerular filtration rate eGFR, C-reactive protein, left ventricular ejection fraction, and ELR were independent predictors of CIN. Conclusion: ELR could be an effective and reliable marker to predict CIN development in individuals with STEMI who undergo primary PCI. Early prediction of CIN risk is critical to provide intensive preventive measures for high-risk patients.

 Aims: Inflammation is considered a major contributor to the development of contrast-induced nephropathy CIN. The purpose of this study was to assess the effectiveness of eosinophil-to-lymphocyte ratio ELR as a predictor of CIN among patients who experienced percutaneous coronary intervention PCI for ST-segment elevation myocardial infarction STEMI. Methods: The study involved 440 patients diagnosed with STEMI who underwent primary PCI. The participants were categorized into two classes based on whether they had CIN or not. ELR was calculated by dividing the eosinophil count by the lymphocyte count. Results: The group with CIN  showed significantly higher ELR levels 0.1340.063 vs. 0.0690.037, p0.001. According to the ROC curve assessment, the best threshold level of ELR to predict CIN development was identified as 0.093, with 75.9 sensitivity and 79.1 specificity AUC: 0.836; 95 CI: 0.7830.889; p0.001. Logistic regression analysis revealed that estimated glomerular filtration rate eGFR, C-reactive protein, left ventricular ejection fraction, and ELR were independent predictors of CIN. Conclusion: ELR could be an effective and reliable marker to predict CIN development in individuals with STEMI who undergo primary PCI. Early prediction of CIN risk is critical to provide intensive preventive measures for high-risk patients.

 Aims: Inflammation is considered a major contributor to the development of contrast-induced nephropathy CIN. The purpose of this study was to assess the effectiveness of eosinophil-to-lymphocyte ratio ELR as a predictor of CIN among patients who experienced percutaneous coronary intervention PCI for ST-segment elevation myocardial infarction STEMI. Methods: The study involved 440 patients diagnosed with STEMI who underwent primary PCI. The participants were categorized into two classes based on whether they had CIN or not. ELR was calculated by dividing the eosinophil count by the lymphocyte count. Results: The group with CIN  showed significantly higher ELR levels 0.1340.063 vs. 0.0690.037, p0.001. According to the ROC curve assessment, the best threshold level of ELR to predict CIN development was identified as 0.093, with 75.9 sensitivity and 79.1 specificity AUC: 0.836; 95 CI: 0.7830.889; p0.001. Logistic regression analysis revealed that estimated glomerular filtration rate eGFR, C-reactive protein, left ventricular ejection fraction, and ELR were independent predictors of CIN. Conclusion: ELR could be an effective and reliable marker to predict CIN development in individuals with STEMI who undergo primary PCI. Early prediction of CIN risk is critical to provide intensive preventive measures for high-risk patients.

Makale detayları

The diagnostik value of eosinophil-to-lymphocyte ratio in predicting contrast-induced nephropathy in patients with ST-segment elevation myocardial infarction

Yazarlar:

Orhan Karayiğit | Murat Gök | Ahmet Balun | Alparslan Kurtul

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.120-125

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343176

pISSN:

2718-0115

Eosinophil-to-lymphocyte ratio

contrast-induced nephropathy

percutaneous coronary intervention

ST-segment elevation myocardial infarction

Sayı

Makale detayları

The diagnostik value of eosinophil-to-lymphocyte ratio in predicting contrast-induced nephropathy in patients with ST-segment elevation myocardial infarction

Yazarlar: Orhan Karayiğit | Murat Gök | Ahmet Balun | Alparslan Kurtul

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Kardiyoloji

Dergi: Anatolian Current Medical Journal Vol.7 Issue 2, pp.120-125

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001343176

pISSN: 2718-0115

Eosinophil-to-lymphocyte ratio

contrast-induced nephropathy

percutaneous coronary intervention

ST-segment elevation myocardial infarction

Sayı

Yazarlar:

Orhan Karayiğit | Murat Gök | Ahmet Balun | Alparslan Kurtul

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.120-125

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343176

pISSN:

2718-0115