Chemical Characterizations and Biological Evaluation of Papaya (Carica papaya L.) Essential Oils and Fatty Acids

Eda Türker; Hamide Gübbük; Gözde Öztürk; Betül Demirci

Makale detayları

Chemical Characterizations and Biological Evaluation of Papaya (Carica papaya L.) Essential Oils and Fatty Acids

Yazarlar:

Eda Türker | Hamide Gübbük | Gözde Öztürk | Betül Demirci

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.26 Issue 6, pp.1771-1779

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347787

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The genus Carica L. Caricaceae is presented by 22 species where C. papaya L. is the most widely cultivated and best-known species. It is native in Middle and South America, and consumed for its nutritional values. Also, its medicinal uses such as antimicrobial, antihelmintic, antifungal, hepatoprotective and diuretic among others are known. In this present study, it was aimed to analyse the chemical compositions of C. papaya cv. Sel 42 essential and fatty oils from Antalya cultivars. Essential oils EOs from leaf, ripe and unripe fruits of C. papaya were obtained by hydrodistillation using a Clevenger type apparatus. The essential oils were subsequently analysed by both Gas chromatography GC and Gas chromatography-Mass spectrometry GC-MS. Benzyl isothiocyanate 86.3; 100; 94.4 was found as the main constituent of the EOs of C. papaya leaf, ripe and unripe fruits, respectively. Dried and fresh seeds of C. papaya fatty acids FAs were extracted with n-hexane in a Soxhlet apparatus, and after the methylation the chemical compositions were determined by GC and GC-MS systems. The major FAs of both dried and fresh seeds of C. papaya were oleic acid 72; 70, palmitic acid 15; 16.4, linoleic acid 5.3; 5.1, respectively. The C. papaya EOs and FAs were evaluated also for their in vitro antimicrobial properties against different microbial strains by the agar disk well diffusion method. The EOs and FAs showed relatively weak antimicrobial activity against the tested Escherichia coli NRRL B-3008, Bacillus subtilis NRRL B-4378, and Candida albicans ATCC 10231, respectively. Further biological evaluations are ongoing.

 The genus Carica L. Caricaceae is presented by 22 species where C. papaya L. is the most widely cultivated and best-known species. It is native in Middle and South America, and consumed for its nutritional values. Also, its medicinal uses such as antimicrobial, antihelmintic, antifungal, hepatoprotective and diuretic among others are known. In this present study, it was aimed to analyse the chemical compositions of C. papaya cv. Sel 42 essential and fatty oils from Antalya cultivars. Essential oils EOs from leaf, ripe and unripe fruits of C. papaya were obtained by hydrodistillation using a Clevenger type apparatus. The essential oils were subsequently analysed by both Gas chromatography GC and Gas chromatography-Mass spectrometry GC-MS. Benzyl isothiocyanate 86.3; 100; 94.4 was found as the main constituent of the EOs of C. papaya leaf, ripe and unripe fruits, respectively. Dried and fresh seeds of C. papaya fatty acids FAs were extracted with n-hexane in a Soxhlet apparatus, and after the methylation the chemical compositions were determined by GC and GC-MS systems. The major FAs of both dried and fresh seeds of C. papaya were oleic acid 72; 70, palmitic acid 15; 16.4, linoleic acid 5.3; 5.1, respectively. The C. papaya EOs and FAs were evaluated also for their in vitro antimicrobial properties against different microbial strains by the agar disk well diffusion method. The EOs and FAs showed relatively weak antimicrobial activity against the tested Escherichia coli NRRL B-3008, Bacillus subtilis NRRL B-4378, and Candida albicans ATCC 10231, respectively. Further biological evaluations are ongoing.

 The genus Carica L. Caricaceae is presented by 22 species where C. papaya L. is the most widely cultivated and best-known species. It is native in Middle and South America, and consumed for its nutritional values. Also, its medicinal uses such as antimicrobial, antihelmintic, antifungal, hepatoprotective and diuretic among others are known. In this present study, it was aimed to analyse the chemical compositions of C. papaya cv. Sel 42 essential and fatty oils from Antalya cultivars. Essential oils EOs from leaf, ripe and unripe fruits of C. papaya were obtained by hydrodistillation using a Clevenger type apparatus. The essential oils were subsequently analysed by both Gas chromatography GC and Gas chromatography-Mass spectrometry GC-MS. Benzyl isothiocyanate 86.3; 100; 94.4 was found as the main constituent of the EOs of C. papaya leaf, ripe and unripe fruits, respectively. Dried and fresh seeds of C. papaya fatty acids FAs were extracted with n-hexane in a Soxhlet apparatus, and after the methylation the chemical compositions were determined by GC and GC-MS systems. The major FAs of both dried and fresh seeds of C. papaya were oleic acid 72; 70, palmitic acid 15; 16.4, linoleic acid 5.3; 5.1, respectively. The C. papaya EOs and FAs were evaluated also for their in vitro antimicrobial properties against different microbial strains by the agar disk well diffusion method. The EOs and FAs showed relatively weak antimicrobial activity against the tested Escherichia coli NRRL B-3008, Bacillus subtilis NRRL B-4378, and Candida albicans ATCC 10231, respectively. Further biological evaluations are ongoing.

 The genus Carica L. Caricaceae is presented by 22 species where C. papaya L. is the most widely cultivated and best-known species. It is native in Middle and South America, and consumed for its nutritional values. Also, its medicinal uses such as antimicrobial, antihelmintic, antifungal, hepatoprotective and diuretic among others are known. In this present study, it was aimed to analyse the chemical compositions of C. papaya cv. Sel 42 essential and fatty oils from Antalya cultivars. Essential oils EOs from leaf, ripe and unripe fruits of C. papaya were obtained by hydrodistillation using a Clevenger type apparatus. The essential oils were subsequently analysed by both Gas chromatography GC and Gas chromatography-Mass spectrometry GC-MS. Benzyl isothiocyanate 86.3; 100; 94.4 was found as the main constituent of the EOs of C. papaya leaf, ripe and unripe fruits, respectively. Dried and fresh seeds of C. papaya fatty acids FAs were extracted with n-hexane in a Soxhlet apparatus, and after the methylation the chemical compositions were determined by GC and GC-MS systems. The major FAs of both dried and fresh seeds of C. papaya were oleic acid 72; 70, palmitic acid 15; 16.4, linoleic acid 5.3; 5.1, respectively. The C. papaya EOs and FAs were evaluated also for their in vitro antimicrobial properties against different microbial strains by the agar disk well diffusion method. The EOs and FAs showed relatively weak antimicrobial activity against the tested Escherichia coli NRRL B-3008, Bacillus subtilis NRRL B-4378, and Candida albicans ATCC 10231, respectively. Further biological evaluations are ongoing.

Makale detayları

Chemical Characterizations and Biological Evaluation of Papaya (Carica papaya L.) Essential Oils and Fatty Acids

Yazarlar: Eda Türker | Hamide Gübbük | Gözde Öztürk | Betül Demirci

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.26 Issue 6, pp.1771-1779

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001347787

pISSN: 2630-6344

Carica papaya L.

Caricaceae

essential oil

fatty oil

antimicrobial activity

Sayı

Yazarlar:

Eda Türker | Hamide Gübbük | Gözde Öztürk | Betül Demirci

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.26 Issue 6, pp.1771-1779

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347787

pISSN:

2630-6344