Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Ayhan ATIGAN; Yeliz ARMAN KARAKAYA; Umit CABUS

doi:https://doi.org/10.5472/marumj.925209

Makale detayları

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Yazarlar:

Ayhan ATIGAN | Yeliz ARMAN KARAKAYA | Umit CABUS

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 2021 Vol.34 Issue 2, pp.167-174

Belge Tipi:

Makale

Yayın Tarihi:

5/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000544093

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941

DOI:

https://doi.org/10.5472/marumj.925209

Özet:

 

Objectives: Mature cystic teratomas (MCT) originate from three germ layers: ectoderm, mesoderm and endoderm. The predictive
significance of tumor markers in mature cystic teratomas is still unclear. In this study, we aimed to evaluate the predictive value of
tumor markers in ovarian MCTs and histopathological contents of tumor.
Materials and Methods: The data of 106 patients who were operated for ovarian MCT between 2015 and 2020 were analyzed
retrospectively. In addition, slides in the pathology archive were re-examined under a microscope to evaluate their histopathological
contents.
Results: The average age of the patients was 35.7; 26.7 in the cystectomy group and 42.1 in the oophorectomy group (p = 0.000). The
ratio of tumor markers exceeding the cut off value for carbohydrate antigen (CA 19-9), lactate dehydrogenase (LDH), cancer antigen
(CA 125), carcinoma antigen (CA 15-3), carcinoembryonic antigen (CEA) were 45.2%; 47.7%; 8.15%; 12.3%; 6.9%, respectively.
Histopathological examination of MCTs revealed 99.1% ectoderm, 45.3% mesodermal, 39.6% endodermal origin.
Conclusion: Mature cystic teratoma is a benign tumor of the reproductive age that contains three germ layers in various proportions.
LDH and CA 19-9 can be a helpful tool in predicting mature cystic teratomas.

Makale detayları

Mature cystic ovarian teratomas: Relationship between histopathological contents and clinical features

Yazarlar: Ayhan ATIGAN | Yeliz ARMAN KARAKAYA | Umit CABUS

Yayıncı: Marmara University

Ana Başlıklar: Hastalıklar

Dergi: Marmara Medical Journal 2021 Vol.34 Issue 2, pp.167-174

Belge Tipi: Makale

Yayın Tarihi: 5/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000544093

Sıklık: Aylık

eISSN: 1309-9469

pISSN: 1019-1941

DOI: https://doi.org/10.5472/marumj.925209

Sayı

Yazarlar:

Ayhan ATIGAN | Yeliz ARMAN KARAKAYA | Umit CABUS

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 2021 Vol.34 Issue 2, pp.167-174

Belge Tipi:

Makale

Yayın Tarihi:

5/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000544093

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941

DOI:

https://doi.org/10.5472/marumj.925209