Effect of vaccine on prognosis and mortality in COVID-19

Selda Tekin; Nilufer Coskum; Esra Adıyeke; Erman Şen; Ozgun Topcuoglu Sarı; Mücahit Uğur Aygün; Ayşe Şabablı Çetin; Fatma Yılmaz-karadağ; Nurten Bakan

Makale detayları

Effect of vaccine on prognosis and mortality in COVID-19

Yazarlar:

Selda Tekin | Nilufer Coskum | Esra Adıyeke | Erman Şen | Ozgun Topcuoglu Sarı | Mücahit Uğur Aygün | Ayşe Şabablı Çetin | Fatma Yılmaz-karadağ | Nurten Bakan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282272

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aim: The aim of our study is to reveal the factors affecting the clinical course of COVID-19 infection and mortality in immune and non-immune patients aged 65 and over. Material and Method: The study was carried out by scanning the files of a total of 1,642 COVID-19 cases aged 65 and over. The 1337 cases included in the study were divided into two groups as follows: patients who were vaccinated with the 2nd dose of CoronaVac but became infected with COVID-19 after the 14-day period in which immunization should develop Group I and the others who were unvaccinated, or infected with COVID-19 after a single dose of vaccination or infected after receiving a 2nd dose of vaccination in 14 days Group II. The groups were compared with each other about mortality and the factors affecting mortality. Results: The length of intensive care unit ICU stay, and the total length of hospital stay were significantly longer in Group II than Group I p0.05. The need for mechanical ventilation MV and the length of MV were also significantly higher in Group II than Group I p0.05. All patients enrolled in the study had lung involvement. The percentage of Computed tomography CT involvement over 50 was statistically significant in Group II p0.05. The percentage of severe and critically severe patients and mortality were significantly high in Group II vs. Group I p0.05. Conclusion: When we compared the vaccinated and unvaccinated groups of 65 years of age, we found that hospitalization in the ICU and the need for MV increased mortality, and the vaccine reduced the need for intensive care and MV.

 Aim: The aim of our study is to reveal the factors affecting the clinical course of COVID-19 infection and mortality in immune and non-immune patients aged 65 and over. Material and Method: The study was carried out by scanning the files of a total of 1,642 COVID-19 cases aged 65 and over. The 1337 cases included in the study were divided into two groups as follows: patients who were vaccinated with the 2nd dose of CoronaVac but became infected with COVID-19 after the 14-day period in which immunization should develop Group I and the others who were unvaccinated, or infected with COVID-19 after a single dose of vaccination or infected after receiving a 2nd dose of vaccination in 14 days Group II. The groups were compared with each other about mortality and the factors affecting mortality. Results: The length of intensive care unit ICU stay, and the total length of hospital stay were significantly longer in Group II than Group I p0.05. The need for mechanical ventilation MV and the length of MV were also significantly higher in Group II than Group I p0.05. All patients enrolled in the study had lung involvement. The percentage of Computed tomography CT involvement over 50 was statistically significant in Group II p0.05. The percentage of severe and critically severe patients and mortality were significantly high in Group II vs. Group I p0.05. Conclusion: When we compared the vaccinated and unvaccinated groups of 65 years of age, we found that hospitalization in the ICU and the need for MV increased mortality, and the vaccine reduced the need for intensive care and MV.

 Aim: The aim of our study is to reveal the factors affecting the clinical course of COVID-19 infection and mortality in immune and non-immune patients aged 65 and over. Material and Method: The study was carried out by scanning the files of a total of 1,642 COVID-19 cases aged 65 and over. The 1337 cases included in the study were divided into two groups as follows: patients who were vaccinated with the 2nd dose of CoronaVac but became infected with COVID-19 after the 14-day period in which immunization should develop Group I and the others who were unvaccinated, or infected with COVID-19 after a single dose of vaccination or infected after receiving a 2nd dose of vaccination in 14 days Group II. The groups were compared with each other about mortality and the factors affecting mortality. Results: The length of intensive care unit ICU stay, and the total length of hospital stay were significantly longer in Group II than Group I p0.05. The need for mechanical ventilation MV and the length of MV were also significantly higher in Group II than Group I p0.05. All patients enrolled in the study had lung involvement. The percentage of Computed tomography CT involvement over 50 was statistically significant in Group II p0.05. The percentage of severe and critically severe patients and mortality were significantly high in Group II vs. Group I p0.05. Conclusion: When we compared the vaccinated and unvaccinated groups of 65 years of age, we found that hospitalization in the ICU and the need for MV increased mortality, and the vaccine reduced the need for intensive care and MV.

 Aim: The aim of our study is to reveal the factors affecting the clinical course of COVID-19 infection and mortality in immune and non-immune patients aged 65 and over. Material and Method: The study was carried out by scanning the files of a total of 1,642 COVID-19 cases aged 65 and over. The 1337 cases included in the study were divided into two groups as follows: patients who were vaccinated with the 2nd dose of CoronaVac but became infected with COVID-19 after the 14-day period in which immunization should develop Group I and the others who were unvaccinated, or infected with COVID-19 after a single dose of vaccination or infected after receiving a 2nd dose of vaccination in 14 days Group II. The groups were compared with each other about mortality and the factors affecting mortality. Results: The length of intensive care unit ICU stay, and the total length of hospital stay were significantly longer in Group II than Group I p0.05. The need for mechanical ventilation MV and the length of MV were also significantly higher in Group II than Group I p0.05. All patients enrolled in the study had lung involvement. The percentage of Computed tomography CT involvement over 50 was statistically significant in Group II p0.05. The percentage of severe and critically severe patients and mortality were significantly high in Group II vs. Group I p0.05. Conclusion: When we compared the vaccinated and unvaccinated groups of 65 years of age, we found that hospitalization in the ICU and the need for MV increased mortality, and the vaccine reduced the need for intensive care and MV.

Makale detayları

Effect of vaccine on prognosis and mortality in COVID-19

Yazarlar:

Selda Tekin | Nilufer Coskum | Esra Adıyeke | Erman Şen | Ozgun Topcuoglu Sarı | Mücahit Uğur Aygün | Ayşe Şabablı Çetin | Fatma Yılmaz-karadağ | Nurten Bakan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282272

pISSN:

2636-8579

Vaccine

COVID-19

elder age

Vaccine

COVID-19

elder age

Sayı

Makale detayları

Effect of vaccine on prognosis and mortality in COVID-19

Yazarlar: Selda Tekin | Nilufer Coskum | Esra Adıyeke | Erman Şen | Ozgun Topcuoglu Sarı | Mücahit Uğur Aygün | Ayşe Şabablı Çetin | Fatma Yılmaz-karadağ | Nurten Bakan

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.7-12

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282272

pISSN: 2636-8579

Vaccine

COVID-19

elder age

Vaccine

COVID-19

elder age

Sayı

Yazarlar:

Selda Tekin | Nilufer Coskum | Esra Adıyeke | Erman Şen | Ozgun Topcuoglu Sarı | Mücahit Uğur Aygün | Ayşe Şabablı Çetin | Fatma Yılmaz-karadağ | Nurten Bakan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282272

pISSN:

2636-8579