Türk Toplumundaki Gestasyonel Diabetes Mellitus’lu Gebelerde  Helicobacter pylori Seropozitivitesi Insidansı

Adile Yeşim AKDEMİR; İrem DARKA; Ülkü ÖZMEN; Müge HARMA; Mehmet HARMA

Makale detayları

Türk Toplumundaki Gestasyonel Diabetes Mellitus’lu Gebelerde Helicobacter pylori Seropozitivitesi Insidansı

Yazarlar:

Adile Yeşim AKDEMİR | İrem DARKA | Ülkü ÖZMEN | Müge HARMA | Mehmet HARMA

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Diabetes and Obesity 2019 Vol.3 Issue 3, pp.149-153

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000705438

Sıklık:

Üç Yıllık

eISSN:

2587-0572

pISSN:

2587-0335

Özet:

 


Aim: The aim of this study to determine the Helicobacter pylori (HP) seropositivity in pregnant Turkish women and investigate the relationship with Gestational Diabetus Mellitus (GDM) with HP. 

Material and Methods: A prospective case control study was conducted between September and November 2019 at Zonguldak Bulent Ecevit University, School of Medicine, Obstetrics and Gynecology Department. Pregnant women who were 18-40 years old, at 26-37 weeks of gestational age and had singleton pregnancies included. Exclusion criteria were: Multiple pregnancy, pre-gestational diabetes mellitus, hypertension, hyperlipidemia, anemia and other systemic diseases. Study group was consisted of 46 women with diagnosed as GDM due to 75 gr oral glucose test and control group was consisted of 28 women. HP IgA ve IgG antibodies were measured using ELISA. Women were considered as HP (+) when IgA and/or IgG antibodies were positive, and considered as HP (-)  when both antibodies were negative.

Results: No difference were seen in maternal age, gravidity, parity, abortus, gestational age, ultrasonographic age, and estimated fetal weight between two groups. Body mass index, fasting blood glucose and fasting insulin levels, and HOMA-IR were significantly higher in GDM group than control group (p=0.018; p=<0.001; p=0.004; p=0.001 respectively).  HP seropositivity were 77.3% in GDM group and 66.7% in control group but this difference was not statistically significant. HP IgG seropositivity was significantly higher in GDM group than control group (65.9% vs 31.8%, p=0,010). On the other hand HP IgA incidence was not different between two groups. Presence of both HP IgG and IgA seropositivity was higher in GDM group (28.2% vs 10.71%, GDM and control groups respectively, p= 0.008).   

Conclusion: Incidence of HP seropositivity and HP IgG seropositivity in Turkish pregnant women with GDM were higher than pregnant women without GDM, but statistical significance could not be established in aspect of HP seropositivity. This data will be helpful for future studies that will investigate relation between HP seropositivity and pregnancy complications. 

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Makale detayları

Türk Toplumundaki Gestasyonel Diabetes Mellitus’lu Gebelerde Helicobacter pylori Seropozitivitesi Insidansı

Yazarlar: Adile Yeşim AKDEMİR | İrem DARKA | Ülkü ÖZMEN | Müge HARMA | Mehmet HARMA

Yayıncı: Zonguldak Bulent Ecevit University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Turkish Journal of Diabetes and Obesity 2019 Vol.3 Issue 3, pp.149-153

Belge Tipi: Makale

Yayın Tarihi: 12/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000705438

Sıklık: Üç Yıllık

eISSN: 2587-0572

pISSN: 2587-0335

Sayı

Yazarlar:

Adile Yeşim AKDEMİR | İrem DARKA | Ülkü ÖZMEN | Müge HARMA | Mehmet HARMA

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Diabetes and Obesity 2019 Vol.3 Issue 3, pp.149-153

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000705438

Sıklık:

Üç Yıllık

eISSN:

2587-0572

pISSN:

2587-0335