Histochemical and Fluorescent Labelling of  Neurons Projecting to Nucleus Accumbens: the  Relation to Pain Processing

Gülgün KAYALIOĞLU

Makale detayları

Histochemical and Fluorescent Labelling of Neurons Projecting to Nucleus Accumbens: the Relation to Pain Processing

Yazarlar:

Gülgün KAYALIOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 3, pp.219-230

Belge Tipi:

Makale

Yayın Tarihi:

2/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

This study was undertaken to  examine the laminar distribution of spinotelencephalic  tract neurons in the rat, by means  of retrograde fluorescent labelling and to  estimate the role of NADPH-diaphorase-reactive  spinal cells as sources of spino-supraspinal  pathways in the rat. The localization,  size and shape of some neurons were  similar in both labelling methods. Cells were  mostly multipolar in the medial part of nucl.  proprius, and fusiform and spindle-shaped in  lamina I and X. It is suggested that some of  the NADPH-d (+) neurons in the deep dorsal  horn and lamina X are sources of a spino-supraspinal  pathway to nucleus accumbens  and the excitability and spontaneous activity  of these dynamic neurons may be higher  when spinally mediated hyperalgesia is developed.

 

This study was undertaken to  examine the laminar distribution of spinotelencephalic  tract neurons in the rat, by means  of retrograde fluorescent labelling and to  estimate the role of NADPH-diaphorase-reactive  spinal cells as sources of spino-supraspinal  pathways in the rat. The localization,  size and shape of some neurons were  similar in both labelling methods. Cells were  mostly multipolar in the medial part of nucl.  proprius, and fusiform and spindle-shaped in  lamina I and X. It is suggested that some of  the NADPH-d (+) neurons in the deep dorsal  horn and lamina X are sources of a spino-supraspinal  pathway to nucleus accumbens  and the excitability and spontaneous activity  of these dynamic neurons may be higher  when spinally mediated hyperalgesia is developed.

Makale detayları

Histochemical and Fluorescent Labelling of Neurons Projecting to Nucleus Accumbens: the Relation to Pain Processing

Yazarlar:

Gülgün KAYALIOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 3, pp.219-230

Belge Tipi:

Makale

Yayın Tarihi:

2/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Nucleus accumbens

Nociception

Hyperalgesia

NADPH-diaphorase

Fluoro-Gold

Sayı

Makale detayları

Histochemical and Fluorescent Labelling of Neurons Projecting to Nucleus Accumbens: the Relation to Pain Processing

Yazarlar: Gülgün KAYALIOĞLU

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1998 Vol.28 Issue 3, pp.219-230

Belge Tipi: Makale

Yayın Tarihi: 2/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000758360

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Nucleus accumbens

Nociception

Hyperalgesia

NADPH-diaphorase

Fluoro-Gold

Sayı

Yazarlar:

Gülgün KAYALIOĞLU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 3, pp.219-230

Belge Tipi:

Makale

Yayın Tarihi:

2/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758360

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144