Abnormal Uterine Bleeding in Adolescents: Treatment with Combined Oral Contraceptive Pills is Effective Even in Hospitalized Patients with Bleeding Disorders

M. Metin ALTAY

Makale detayları

Abnormal Uterine Bleeding in Adolescents: Treatment with Combined Oral Contraceptive Pills is Effective Even in Hospitalized Patients with Bleeding Disorders

Yazarlar:

M. Metin ALTAY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 5, pp.431-435

Belge Tipi:

Makale

Yayın Tarihi:

4/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755716

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Aims: To show the efficacy of oral contraceptive (OC) treatment for hospitalized adolescent patients with abnormal uterine bleeding (AUB).  Materials and Methods: Thirty-one girls with AUB and anemia hospitalized within the last two years were included. The patients´ medical records were evaluated retrospectively. All patients were given combined OC containing 0.03 mg ethinyl estradiol plus 0.15 mg desogestrel according to a defined protocol.   Results: Among 31 patients, 8 (25.8%) had bleeding disorders: 3 (9.7%) had factor VII deficiency, 3 (9.7%) thrombocytopenia, 1 (3.2%) factor VIII deficiency and 1 (3.2%) von Willebrand disease. Vaginal bleeding stopped in all patients within a few days with the treatment protocol.   Conclusions: Adolescents are good responders to medical treatment despite the presence of bleeding disorders, probably due to the positive coagulative effect of the estrogen component of OCs on platelets and clotting factors. Continuation of OC will be a problem in adolescent girls, because there are some misconceptions about OC in the Turkish population, such as that OC can cause infertility or hormonal imbalance. Appropriate counselling is necessary to overcome this difficulty. We believe that the presence of an Adolescent Gynecology Unit affected the success of our treatment.

 

Aims: To show the efficacy of oral contraceptive (OC) treatment for hospitalized adolescent patients with abnormal uterine bleeding (AUB).  Materials and Methods: Thirty-one girls with AUB and anemia hospitalized within the last two years were included. The patients´ medical records were evaluated retrospectively. All patients were given combined OC containing 0.03 mg ethinyl estradiol plus 0.15 mg desogestrel according to a defined protocol.   Results: Among 31 patients, 8 (25.8%) had bleeding disorders: 3 (9.7%) had factor VII deficiency, 3 (9.7%) thrombocytopenia, 1 (3.2%) factor VIII deficiency and 1 (3.2%) von Willebrand disease. Vaginal bleeding stopped in all patients within a few days with the treatment protocol.   Conclusions: Adolescents are good responders to medical treatment despite the presence of bleeding disorders, probably due to the positive coagulative effect of the estrogen component of OCs on platelets and clotting factors. Continuation of OC will be a problem in adolescent girls, because there are some misconceptions about OC in the Turkish population, such as that OC can cause infertility or hormonal imbalance. Appropriate counselling is necessary to overcome this difficulty. We believe that the presence of an Adolescent Gynecology Unit affected the success of our treatment.

Makale detayları

Abnormal Uterine Bleeding in Adolescents: Treatment with Combined Oral Contraceptive Pills is Effective Even in Hospitalized Patients with Bleeding Disorders

Yazarlar:

M. Metin ALTAY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 5, pp.431-435

Belge Tipi:

Makale

Yayın Tarihi:

4/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755716

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Dysfunctional uterine bleeding

adolescence

bleeding disorder

ethinyl estradiol

desogestrel

Sayı

Makale detayları

Abnormal Uterine Bleeding in Adolescents: Treatment with Combined Oral Contraceptive Pills is Effective Even in Hospitalized Patients with Bleeding Disorders

Yazarlar: M. Metin ALTAY

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2008 Vol.38 Issue 5, pp.431-435

Belge Tipi: Makale

Yayın Tarihi: 4/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000755716

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Dysfunctional uterine bleeding

adolescence

bleeding disorder

ethinyl estradiol

desogestrel

Sayı

Yazarlar:

M. Metin ALTAY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 5, pp.431-435

Belge Tipi:

Makale

Yayın Tarihi:

4/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755716

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144