A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines

Çağla Begüm APAYDIN; Zafer CESUR

Makale detayları

A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines

Yazarlar:

Çağla Begüm APAYDIN | Zafer CESUR

Yayıncı:

Istanbul University

Ana Başlıklar:

Farmakoloji ve terapötik

Dergi:

İstanbul Journal of Pharmacy 2019 Vol.49 Issue 2, pp.61-63

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000513022

Sıklık:

Aylık

eISSN:

2587-2087

Özet:

 


DOI: 10.26650/IstanbulJPharm.2019.19002


This report is about an unexpected
formation of N,N’-bis(substituted phenoxyacetyl) hydrazine derivatives. The
reaction between N’-(4-ethylcyclohexylidene)phenoxyacetohydrazide with sulfanyl
acids to obtain 4-thiazolidinones s, 
gave an unexpected product, N,N’-bis(phenoxyacetyl)hydrazine, with high
purity instead of the expected cyclocondensation product.  When repeating the reaction with p-toluenesulfonic
acid under the same conditions, the reaction resulted in the same compound.
This indicates that two molecules of
N’-(4-ethylcyclohexylidene)phenoxyacetohydrazide were involved in the reaction.
The reaction can be applied as a different and new procedure for the synthesis
of several N,N’-bis(substituted phenoxyacetyl)hydrazine derivatives. 

Cite this article as: Apaydın ÇB, Cesur Z
(2019). A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines.
Istanbul J Pharm 49 (2): 61-63.


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Makale detayları

A new approach for the synthesis of N,N’-bis(phenoxyacetyl)hydrazines

Yazarlar: Çağla Begüm APAYDIN | Zafer CESUR

Yayıncı: Istanbul University

Ana Başlıklar: Farmakoloji ve terapötik

Dergi: İstanbul Journal of Pharmacy 2019 Vol.49 Issue 2, pp.61-63

Belge Tipi: Makale

Yayın Tarihi: 7/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000513022

Sıklık: Aylık

eISSN: 2587-2087

Sayı

Yazarlar:

Çağla Begüm APAYDIN | Zafer CESUR

Yayıncı:

Istanbul University

Ana Başlıklar:

Farmakoloji ve terapötik

Dergi:

İstanbul Journal of Pharmacy 2019 Vol.49 Issue 2, pp.61-63

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000513022

Sıklık:

Aylık

eISSN:

2587-2087