The relationship between canlph score and saphenous vein graft disease

Serafettin	demir Serafettin	demır; Armağan Acele; Arafat Yıldırım; Ozge Ozcan Abacıoglu

Makale detayları

The relationship between canlph score and saphenous vein graft disease

Yazarlar:

Serafettin demir Serafettin demır | Armağan Acele | Arafat Yıldırım | Ozge Ozcan Abacıoglu

Yayıncı:

Mersin University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Mersin Üniversitesi Sağlık Bilimleri Dergisi Vol.16 Issue 1, pp.14-21

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287367

pISSN:

1308-0830

Anahtar kelimeler:

Özet:

 Objective: The frequency and clinical presentation of saphenous vein graft disease SVGD is increasing so it is important to reveal the predisposing factors and identify the patients in the risk group. In this study; We aimed to evaluate the relationship between CRPalbumin ratio neutrophillymphocyte ratio platelethemoglobin ratio CANLPH score and SVGD, which enables the evaluation of three biomarkers such as platelethemoglobin ratio PHR, CRPalbumin ratio CAR and neutrophillymphocyte ratio NLR. Method: Total of 754 patients who had coronary angiography in our hospital between January 2018 and January 2020 and had history of coronary artery bypass graft were included retrospectively. Patients with stenosis of at least 50 in SVGs constituted the SVGH group and without stenosis in SVGs the controls. CAR, NLR and PHR values were calculated and cut-off values were determined using the Youden index and scores were obtained as 0 or 1. The sum of these 3 scores was recorded as the CANLPH score. A p value of 0.05 was considered statistically significant. Results: The mean age of all patients was 66.08.6 73 male. The patients in SVGD group n372 were more diabetic and had lower ejection fraction than controls p0.041 and p0.001. The groups were similar in terms of PHR p0.690 but mean CAR p0.001 and NLR p0.003 were higher in SVGD group. In multivariate logistic regression analysis CANLPH, CAR, NLR, lower EF and higher glucose were independent predictors of SVGD. CANLPH score was better with an Area under curve AUC 0.663 and p0.001, 95 confidence Interval CI :0.620-0.705. Conclusion: CANLPH score can be a laboratory biomarker for predicting SVGD.

 Objective: The frequency and clinical presentation of saphenous vein graft disease SVGD is increasing so it is important to reveal the predisposing factors and identify the patients in the risk group. In this study; We aimed to evaluate the relationship between CRPalbumin ratio neutrophillymphocyte ratio platelethemoglobin ratio CANLPH score and SVGD, which enables the evaluation of three biomarkers such as platelethemoglobin ratio PHR, CRPalbumin ratio CAR and neutrophillymphocyte ratio NLR. Method: Total of 754 patients who had coronary angiography in our hospital between January 2018 and January 2020 and had history of coronary artery bypass graft were included retrospectively. Patients with stenosis of at least 50 in SVGs constituted the SVGH group and without stenosis in SVGs the controls. CAR, NLR and PHR values were calculated and cut-off values were determined using the Youden index and scores were obtained as 0 or 1. The sum of these 3 scores was recorded as the CANLPH score. A p value of 0.05 was considered statistically significant. Results: The mean age of all patients was 66.08.6 73 male. The patients in SVGD group n372 were more diabetic and had lower ejection fraction than controls p0.041 and p0.001. The groups were similar in terms of PHR p0.690 but mean CAR p0.001 and NLR p0.003 were higher in SVGD group. In multivariate logistic regression analysis CANLPH, CAR, NLR, lower EF and higher glucose were independent predictors of SVGD. CANLPH score was better with an Area under curve AUC 0.663 and p0.001, 95 confidence Interval CI :0.620-0.705. Conclusion: CANLPH score can be a laboratory biomarker for predicting SVGD.

 Objective: The frequency and clinical presentation of saphenous vein graft disease SVGD is increasing so it is important to reveal the predisposing factors and identify the patients in the risk group. In this study; We aimed to evaluate the relationship between CRPalbumin ratio neutrophillymphocyte ratio platelethemoglobin ratio CANLPH score and SVGD, which enables the evaluation of three biomarkers such as platelethemoglobin ratio PHR, CRPalbumin ratio CAR and neutrophillymphocyte ratio NLR. Method: Total of 754 patients who had coronary angiography in our hospital between January 2018 and January 2020 and had history of coronary artery bypass graft were included retrospectively. Patients with stenosis of at least 50 in SVGs constituted the SVGH group and without stenosis in SVGs the controls. CAR, NLR and PHR values were calculated and cut-off values were determined using the Youden index and scores were obtained as 0 or 1. The sum of these 3 scores was recorded as the CANLPH score. A p value of 0.05 was considered statistically significant. Results: The mean age of all patients was 66.08.6 73 male. The patients in SVGD group n372 were more diabetic and had lower ejection fraction than controls p0.041 and p0.001. The groups were similar in terms of PHR p0.690 but mean CAR p0.001 and NLR p0.003 were higher in SVGD group. In multivariate logistic regression analysis CANLPH, CAR, NLR, lower EF and higher glucose were independent predictors of SVGD. CANLPH score was better with an Area under curve AUC 0.663 and p0.001, 95 confidence Interval CI :0.620-0.705. Conclusion: CANLPH score can be a laboratory biomarker for predicting SVGD.

 Amaç: Safen ven greft hastalığının SVGH sıklığı ve klinik prezentasyonu giderek artmaktadır, bu nedenle predispozan faktörlerin ortaya çıkarılması ve risk grubundaki hastaların belirlenmesi önemlidir. Bu çalışmanın amacı, SVGH ile CRPalbümin oranı CAR, nötrofillenfosit oranı NLR ve trombosithemoglobin oranı PHR gibi üç biyobelirtecin değerlendirilmesini sağlayan CRPAlbüminNötrofilLenfositTrombositHemoglobin CANLPH skoru arasındaki ilişkiyi araştırmaktır. Yöntem: Çalışmaya hastanemizde 1 Ocak 2018 - 1 Ocak 2020 tarihleri arasında koroner anjiyografi yapılmış ve koroner arter baypas greft KABG öyküsü olan toplam 754 hasta geriye dönük olarak dahil edilmiştir. SVGlerinin en az birinde ve en az 50 darlığı olan hastalar SVGH grubu ve SVGlerde anlamlı darlığı bulunmayan hastalar kontrol grubu olarak dahil edildi. CAR, NLR ve PHR değerleri hastaların laboratuar verilerinden hesaplandı. Youden indeksi kullanılarak CAR, NLR ve PHR nin limit değerleri belirlendi ve puanlar 0 veya 1 olarak elde edildi. Bu üç skorun puanlarının toplamı ile grupların CANLPH skorları belirlendi. p0.05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Hastaların yaş ortalaması 66.08.6 73 erkek idi. SVGH grubunda n372, Diyabetes Mellitus DM oranı kontrol grubuna n 382 göre göre daha yüksekti ve hastaların ejeksiyon fraksiyonu EF daha düşüktü p0.041 ve p0.001. Gruplar PHR düzeyleri açısından benzerdi ancak ortalama CAR ve NLR skorları SVGH grubunda daha yüksek saptandı. p0.690, p0.001 ve p0.003, sırasıyla. Çok değişkenli regresyon analizinde CANLPH, CAR, NLR, düşük EF ve yüksek glukoz seviyelerinin SVGHnin bağımsız öngördürücüleri olduğu ve CANLPH skorunun, Eğri altındaki alan EAA 0.663 ve p0.001, 95 güven aralığı CI :0.620-0.705 değerleri ile daha iyi olduğu saptandı. Sonuç: Basit ve kolay hesaplanabilen CANLPH skoru, SVGH yi öngördürmede bir laboratuvar biyobelirteci olarak kullanılabilir.

Makale detayları

The relationship between canlph score and saphenous vein graft disease

Yazarlar:

Serafettin demir Serafettin demır | Armağan Acele | Arafat Yıldırım | Ozge Ozcan Abacıoglu

Yayıncı:

Mersin University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Mersin Üniversitesi Sağlık Bilimleri Dergisi Vol.16 Issue 1, pp.14-21

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287367

pISSN:

1308-0830

CANLPH score

coronary artery bypass

saphenous vein graft disease

CANLPH skoru

koroner arter bypass greft

safen ven greft hastalığı

Sayı

Makale detayları

The relationship between canlph score and saphenous vein graft disease

Yazarlar: Serafettin demir Serafettin demır | Armağan Acele | Arafat Yıldırım | Ozge Ozcan Abacıoglu

Yayıncı: Mersin University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Mersin Üniversitesi Sağlık Bilimleri Dergisi Vol.16 Issue 1, pp.14-21

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001287367

pISSN: 1308-0830

CANLPH score

coronary artery bypass

saphenous vein graft disease

CANLPH skoru

koroner arter bypass greft

safen ven greft hastalığı

Sayı

Yazarlar:

Serafettin demir Serafettin demır | Armağan Acele | Arafat Yıldırım | Ozge Ozcan Abacıoglu

Yayıncı:

Mersin University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Mersin Üniversitesi Sağlık Bilimleri Dergisi Vol.16 Issue 1, pp.14-21

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001287367

pISSN:

1308-0830