Synthesis, Characterization and Primary Antituberculosis Activity Evaluation of 4-(3-Coumarinyl)-3-benzyl-4-thiazolin-2-one Benzylidenehydrazones

Aysel GÜRSOY; Nilgün KARALI

Makale detayları

Synthesis, Characterization and Primary Antituberculosis Activity Evaluation of 4-(3-Coumarinyl)-3-benzyl-4-thiazolin-2-one Benzylidenehydrazones

Yazarlar:

Aysel GÜRSOY | Nilgün KARALI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2003 Vol.27 Issue 5, pp.545-552

Belge Tipi:

Makale

Yayın Tarihi:

4/2003

Belge Dili:

Türkçe

Document ID (Org No.):

2000729483

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

In this study a new series of 4-(3-coumarinyl)-3-benzyl-4-thiazolin-  2-one benzylidenehydrazones 3a-t was synthesized.  Structures of the title   compounds were elucidated by elemental analyses and spectrometric data  (IR, 1H-NMR, 13C-NMR and EIMS).  3a-t were evaluated for  antituberculosis activity against Mycobacterium tuberculosis} H37Rv in  BACTEC 12B medium using the BACTEC 460 radiometric system.

 

In this study a new series of 4-(3-coumarinyl)-3-benzyl-4-thiazolin-  2-one benzylidenehydrazones 3a-t was synthesized.  Structures of the title   compounds were elucidated by elemental analyses and spectrometric data  (IR, 1H-NMR, 13C-NMR and EIMS).  3a-t were evaluated for  antituberculosis activity against Mycobacterium tuberculosis} H37Rv in  BACTEC 12B medium using the BACTEC 460 radiometric system.

Makale detayları

Synthesis, Characterization and Primary Antituberculosis Activity Evaluation of 4-(3-Coumarinyl)-3-benzyl-4-thiazolin-2-one Benzylidenehydrazones

Yazarlar: Aysel GÜRSOY | Nilgün KARALI

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2003 Vol.27 Issue 5, pp.545-552

Belge Tipi: Makale

Yayın Tarihi: 4/2003

Belge Dili: Türkçe

Document ID (Org No.): 2000729483

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Aysel GÜRSOY | Nilgün KARALI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2003 Vol.27 Issue 5, pp.545-552

Belge Tipi:

Makale

Yayın Tarihi:

4/2003

Belge Dili:

Türkçe

Document ID (Org No.):

2000729483

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527