Assesment of blood parameters relevant to aterosclerosis and coronary artery disease after paratiroidectomy

Meriç Emre BOSTANCI; Murat Can MOLLAOĞLU; Kürşat KARADAYI

doi:https://doi.org/10.7197/223.vi.504097

Makale detayları

Assesment of blood parameters relevant to aterosclerosis and coronary artery disease after paratiroidectomy

Yazarlar:

Meriç Emre BOSTANCI | Murat Can MOLLAOĞLU | Kürşat KARADAYI

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.438-445

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922679

DOI:

https://doi.org/10.7197/223.vi.504097

Özet:

 


Objective: The
preoperative and postoperative calcium, parathormone levels, platelet counts,
mean platelet volume values of the patients were compared in order to
investigate the changes in the risk of atherosclerosis and coronary artery
disease in parathyroidectomy. 


Method: Twelve male
and 43 female patients who underwent parathyroidectomy between 01.01.2008 and
01.01.2018 at the Cumhuriyet University Surgical Oncology Clinic were included
in the study. On the tenth preoperative and postoperative day, blood was drawn
for the platelet, mean platelet volume, calcium and parathyroid hormone levels
after a fasting period of twelve hours. The preoperative and postoperative
calcium, parathormone levels, platelet counts, mean platelet volume values of
the patients were compared in order to investigate the changes in the risk of
atherosclerosis and coronary artery disease in parathyroidectomy. 


Results: The mean
pre-operative blood calcium levels of the patients included in the study were
10.75 ± 1.49 mg / dl, . Mean postoperative blood calcium level was 8.59 ± 1.14
mg / dl. The mean preoperative mean platelet volume of the patients was 26.1 ±
121.55 fL, Postoperative mean platelet volume was 9.36 ± 1.26 fL. The mean
preoperative parathormone level was 535,08 ± 711,08, The mean postoperative
parathyroid hormone level was 74.47 ± 128.02 pg / ml. The mean preoperative
blood platelet count of the patients included in the study was 418000 ± 8000 /
mm³, The mean postoperative blood platelet count was 252000 ± 7000 / mm³.


Conclusions: In our study,
we found that the decrease in serum parathormone level, serum platelet level,
mean platelet volume, after parathyroidectomy was statistically significant.
Mean platelet volume and platelet count were decreased after parathyroidectomy,
which are indicators of atherosclerosis and coronary artery disease;
Parathyroidectomy reduces the risk of atherosclerosis and coronary artery
disease. Additional clinical and laboratory studies are needed to support the
risk of atherosclerosis and coronary artery disease after parathyroidectomy.


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Makale detayları

Assesment of blood parameters relevant to aterosclerosis and coronary artery disease after paratiroidectomy

Yazarlar: Meriç Emre BOSTANCI | Murat Can MOLLAOĞLU | Kürşat KARADAYI

Ana Başlıklar: Sağlık teşvikleri

Dergi: Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.438-445

Belge Tipi: Makale

Yayın Tarihi: 12/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000922679

DOI: https://doi.org/10.7197/223.vi.504097

Sayı

Yazarlar:

Meriç Emre BOSTANCI | Murat Can MOLLAOĞLU | Kürşat KARADAYI

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.438-445

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922679

DOI:

https://doi.org/10.7197/223.vi.504097