Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience

Asuman Demirbuğa; Sukran Poyrazoglu

Makale detayları

Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience

Yazarlar:

Asuman Demirbuğa | Sukran Poyrazoglu

Yayıncı:

Istanbul University

Ana Başlıklar:

Çocuk Endokrinolojisi

Dergi:

Çocuk Dergisi Vol.24 Issue 3, pp.154-161

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001342383

pISSN:

1308-8491

Anahtar kelimeler:

Özet:

 Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus DM, hypertension, and metabolic syndrome MetS. This study evaluated MetS and type 2 diabetes mellitus DM in overweight and obese children. Methods: Between 2000 and 2013, 474 obese and overweight children aged 18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated. Results: Of the patients, 50.4 n  239 were girls, and the mean age was 10.913.06 years. According to the body mass index, 20.5 n97 of the patients were overweight and 79.5 n377 were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group p 0.05. MetS was found in 30.8 n146 of the patients. The MetS rate was 37.7 n142 in the obese patients and 4.1 n4 in the overweight patients, and the difference between them was statistically significant p0.001 Based on the oral glucose tolerance test; 45 9.5 patients had impaired fasting glycaemia, 24 5 had impaired glucose tolerance and 4 0.84 had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR. Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications.

 Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus DM, hypertension, and metabolic syndrome MetS. This study evaluated MetS and type 2 diabetes mellitus DM in overweight and obese children. Methods: Between 2000 and 2013, 474 obese and overweight children aged 18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated. Results: Of the patients, 50.4 n  239 were girls, and the mean age was 10.913.06 years. According to the body mass index, 20.5 n97 of the patients were overweight and 79.5 n377 were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group p 0.05. MetS was found in 30.8 n146 of the patients. The MetS rate was 37.7 n142 in the obese patients and 4.1 n4 in the overweight patients, and the difference between them was statistically significant p0.001 Based on the oral glucose tolerance test; 45 9.5 patients had impaired fasting glycaemia, 24 5 had impaired glucose tolerance and 4 0.84 had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR. Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications.

 Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus DM, hypertension, and metabolic syndrome MetS. This study evaluated MetS and type 2 diabetes mellitus DM in overweight and obese children. Methods: Between 2000 and 2013, 474 obese and overweight children aged 18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated. Results: Of the patients, 50.4 n  239 were girls, and the mean age was 10.913.06 years. According to the body mass index, 20.5 n97 of the patients were overweight and 79.5 n377 were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group p 0.05. MetS was found in 30.8 n146 of the patients. The MetS rate was 37.7 n142 in the obese patients and 4.1 n4 in the overweight patients, and the difference between them was statistically significant p0.001 Based on the oral glucose tolerance test; 45 9.5 patients had impaired fasting glycaemia, 24 5 had impaired glucose tolerance and 4 0.84 had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR. Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications.

 Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus DM, hypertension, and metabolic syndrome MetS. This study evaluated MetS and type 2 diabetes mellitus DM in overweight and obese children. Methods: Between 2000 and 2013, 474 obese and overweight children aged 18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated. Results: Of the patients, 50.4 n  239 were girls, and the mean age was 10.913.06 years. According to the body mass index, 20.5 n97 of the patients were overweight and 79.5 n377 were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group p 0.05. MetS was found in 30.8 n146 of the patients. The MetS rate was 37.7 n142 in the obese patients and 4.1 n4 in the overweight patients, and the difference between them was statistically significant p0.001 Based on the oral glucose tolerance test; 45 9.5 patients had impaired fasting glycaemia, 24 5 had impaired glucose tolerance and 4 0.84 had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR. Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications.

Makale detayları

Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience

Yazarlar: Asuman Demirbuğa | Sukran Poyrazoglu

Yayıncı: Istanbul University

Ana Başlıklar: Çocuk Endokrinolojisi

Dergi: Çocuk Dergisi Vol.24 Issue 3, pp.154-161

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001342383

pISSN: 1308-8491

Childhood obesity

overweight

metabolic syndrome

type 2 diabetes mellitus

Sayı

Yazarlar:

Asuman Demirbuğa | Sukran Poyrazoglu

Yayıncı:

Istanbul University

Ana Başlıklar:

Çocuk Endokrinolojisi

Dergi:

Çocuk Dergisi Vol.24 Issue 3, pp.154-161

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001342383

pISSN:

1308-8491