The Role of Monocyte to High-Density Lipoprotein Cholesterol Ratio in Prediction of increased systemic inflammation and the risk of cardiovascular disease in endometriosis

İsmail BİYİK; Fatih KESKİN; Nagihan SAZ

Makale detayları

The Role of Monocyte to High-Density Lipoprotein Cholesterol Ratio in Prediction of increased systemic inflammation and the risk of cardiovascular disease in endometriosis

Yazarlar:

İsmail BİYİK | Fatih KESKİN | Nagihan SAZ

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 2, pp.106-110

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507581

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483

Özet:

 

Background and objectives  
Endometriosis occurs in about 5-10 in 100  women of reproductive age. The pathophysiology of endometriosis is controversial. Some studies claimed an association between endometriosis and increased levels of inflammatory factors in peritoneal fluid and/or peripheral blood. Monocyte / HDL cholesterol ratio (MHR) and neutrophil/lymphocyte ratio (NLR) are inflammatory markers and are used as predictors and prognostic indicators of mortality and morbidity in many diseases. In this study, we aimed to  investigate whether Monocyte / HDL cholesterol ratio (MHR) and neutrophil/lymphocyte ratio (NLR) are increased in endometriosis as in patients with chronic inflammation and cardiovascular diseases.
Materials and Methods
This is a retrospective case-control study conducted  with 87 women, 45 in the endometriosis group and 42 in the control group. The demographic data, biochemical, complete blood count parameters and lipid profile of the cases were recorded and compared between the groups.
Results
The mean age of the endometriosis group was 33.88 years and was older than the control group. In terms of other demographic data, there were no difference between the two groups. Although the platelet distribution width and triglyceride values of the endometriosis group were higher than controls, they were interpreted as clinically insignificant. There were no significant differences between the groups in terms of other laboratory parameters including MHR and NLR.
Conclusions
In this study, MHR and NLR are found similar in endometriosis and control groups. Further studies are needed to investigate the relationship between increased systemic inflammation.

Makale detayları

The Role of Monocyte to High-Density Lipoprotein Cholesterol Ratio in Prediction of increased systemic inflammation and the risk of cardiovascular disease in endometriosis

Yazarlar: İsmail BİYİK | Fatih KESKİN | Nagihan SAZ

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 2, pp.106-110

Belge Tipi: Makale

Yayın Tarihi: 4/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000507581

Sıklık: Üç Aylık

eISSN: 1309-5129

pISSN: 1309-4483

Sayı

Yazarlar:

İsmail BİYİK | Fatih KESKİN | Nagihan SAZ

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 2, pp.106-110

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507581

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483