Investigation of Beta-2 microglobulin Levels of Workers Who Exposed to Lead

Oya Torun GÜNGÖR; Ceylan BAL; Müjgan ERCAN; Murat BÜYÜKŞEKERCİ; Mehmet KÖŞ; Fatma Meriç YILMAZ

Makale detayları

Investigation of Beta-2 microglobulin Levels of Workers Who Exposed to Lead

Yazarlar:

Oya Torun GÜNGÖR | Ceylan BAL | Müjgan ERCAN | Murat BÜYÜKŞEKERCİ | Mehmet KÖŞ | Fatma Meriç YILMAZ

Yayıncı:

Engin TUTKUN

Dergi:

The Turkish Journal Of Occupational / Environmental Medicine and Safety 2016 Vol.1 Issue 3, pp.0-0

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000835569

Sıklık:

Üç Aylık

eISSN:

2149-4711

pISSN:

2149-4711

Özet:

 

Lead is a common metal in environment both in nature and in industry because of common usage. Clinical, experimental and epidemiological many studies have proved that lead exposure causes renal damage. In our study we aimed to investigate the tubulary function marker urinary beta-2 microglobulin levels in workers who exposed to lead. A total number of 336 workers of different occupational groups who refered to Ankara Occupational Diseases Hospital toxicology polyclinic for periodical examination were included in the study and separated into two groups; group 1(n=177) and group 2 (n=159) ; whose blood lead levels were >10µg/dL and <10µg/dL, respectively. Lead levels were measured by Agilent 7700 series ICP-MS device, serum blood urea nitrogen and creatinine levels were analyzed by Vitros 5.1 FS device, beta-2 microglobulin levels in 24 hours urine were estimated by micro-ELISA method. SPSS for Windows 18 version was used for statistical analysis. Significance between groups was analyzed by Mann-Whitney U test. Even though 24 hours urine beta-2 microglobulin median levels in the group 1 were higher than the group 2, there was not a statistically significant difference between groups (median: 0.23, 0.21, respectively p=0.713). No significant difference was found between groups by means of serum blood urea nitrogen and creatinine levels (p=0.365; p=0.130 respectively). As a conclusion we did not find a significant difference in blood urea nitrogen and creatinine levels and in beta-2 microglobulin levels in lead exposure.

Makale detayları

Investigation of Beta-2 microglobulin Levels of Workers Who Exposed to Lead

Yazarlar: Oya Torun GÜNGÖR | Ceylan BAL | Müjgan ERCAN | Murat BÜYÜKŞEKERCİ | Mehmet KÖŞ | Fatma Meriç YILMAZ

Yayıncı: Engin TUTKUN

Dergi: The Turkish Journal Of Occupational / Environmental Medicine and Safety 2016 Vol.1 Issue 3, pp.0-0

Belge Tipi: Makale

Yayın Tarihi: 1/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000835569

Sıklık: Üç Aylık

eISSN: 2149-4711

pISSN: 2149-4711

Sayı

Yazarlar:

Oya Torun GÜNGÖR | Ceylan BAL | Müjgan ERCAN | Murat BÜYÜKŞEKERCİ | Mehmet KÖŞ | Fatma Meriç YILMAZ

Yayıncı:

Engin TUTKUN

Dergi:

The Turkish Journal Of Occupational / Environmental Medicine and Safety 2016 Vol.1 Issue 3, pp.0-0

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000835569

Sıklık:

Üç Aylık

eISSN:

2149-4711

pISSN:

2149-4711