Anthelmintic Activity of Ethanol Extract of Polygonum minus Leaves against Ascaridia galli

Dara Agusti Maulidya; Muhammad Ibnu Kahtan; Diana Natalia; Mitra Handini; Ari Vidiyantoro

doi:https://doi.org/10.5799/jmid.403142

Makale detayları

Anthelmintic Activity of Ethanol Extract of Polygonum minus Leaves against Ascaridia galli

Yazarlar:

Dara Agusti Maulidya | Muhammad Ibnu Kahtan | Diana Natalia | Mitra Handini | Ari Vidiyantoro

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2018 Vol.08 Issue 01, pp.23-26

Belge Tipi:

Makale

Yayın Tarihi:

3/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000487424

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.403142

Özet:

 


Anthelmintic Activity of Ethanol
Extract of Polygonum minus Leaves against
Ascaridia galli


Dara Agusti
Maulidya1, Muhammad Ibnu Kahtan2, Diana Natalia2,
Mitra Handini3, Ari Widiyantoro4


1University of Tanjungpura, Faculty
of Medicine,  Pontianak, West Kalimantan, Indonesia


2University of Tanjungpura, Faculty
of Medicine, Department of Parasitology, Pontianak, West Kalimantan, Indonesia


3University of Tanjungpura, Faculty
of Medicine, Department of Physiology, Pontianak, West Kalimantan, Indonesia


4University of Tanjungpura, Faculty
of Mathematics and Science, Department of Chemistry, Pontianak, West
Kalimantan, Indonesia



 

ABSTRACT


Objectives: Helminth infection is one of the main matters that
cause health problems in developing countries. Polygonum minus are empirically used as an anthelmintic drug, but
there has been no scientific study that proves it. 


Methods: This
study was aimed at determining the anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli in vitro. The extract
was prepared in three different concentrations i.e 0.5 mg/mL, 1 mg/mL and 2
mg/mL. NaCl 0.9% was used as a negative control group and albendazole 0.2
mg/mL, a broad spectrum anthelmintic was used as a positive control group. Ascaridia galli was used as the test
parasite. The study involved the determination of death time of the worms. 


Results: The
death time of the worms that caused by the extract concentration 0.5 mg/mL, 1
mg/mL and 2 mg/mL, respectively were (mean±SD) 35±3.32 hours, 32.8±2.39 hours
and 25±3.39 hours. The death time that caused by negative and positive control
group were 76.6±8.30 hours and 19.2±1.48 hours. There is no significant
difference of death time of the worms between the extract concentration 2 mg/mL
and the positive control group. 


Conclusion: The anthelmintic activity of ethanol extract of Polygonum minus leaves has been
confirmed and extract concentration 2 mg/mL has the same anthelmintic activity
with albendazole 0.2 mg/mL. J Microbiol
Infect Dis 2018; 8(1):23-26


Keywords:
Anthelmintic, Polygonum minus, Ascaridia
galli, ascariasis


.

Makale detayları

Anthelmintic Activity of Ethanol Extract of Polygonum minus Leaves against Ascaridia galli

Yazarlar: Dara Agusti Maulidya | Muhammad Ibnu Kahtan | Diana Natalia | Mitra Handini | Ari Vidiyantoro

Yayıncı: Sağlık Araştırmaları Derneği

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Microbiology and Infectious Diseases 2018 Vol.08 Issue 01, pp.23-26

Belge Tipi: Makale

Yayın Tarihi: 3/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000487424

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/jmid.403142

Sayı

Yazarlar:

Dara Agusti Maulidya | Muhammad Ibnu Kahtan | Diana Natalia | Mitra Handini | Ari Vidiyantoro

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2018 Vol.08 Issue 01, pp.23-26

Belge Tipi:

Makale

Yayın Tarihi:

3/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000487424

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.403142