Clinical characteristics and results of patients who underwent minor salivary gland biopsy with the suspicion of Sjogren syndrome

Öznur Kutluk; Fatih Çay

Makale detayları

Clinical characteristics and results of patients who underwent minor salivary gland biopsy with the suspicion of Sjogren syndrome

Yazarlar:

Öznur Kutluk | Fatih Çay

Yayıncı:

Balıkesir University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Balıkesir Medical Journal Vol.8 Issue 3, pp.129-137

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001336820

pISSN:

2564-6664

Anahtar kelimeler:

Özet:

 Objective: To evaluate the value and accuracy of biopsy in diagnosing Sjogren syndrome SS by evaluating the results of patients who underwent mınor salivary gland biopsy MSGB with the suspicion of SS. Material and Methods: The study was planned with a retrospective assessment of 127 patients with a biopsy performed for SS diagnosis. The clinical and laboratory characteristics of the patients who underwent MSGB were recorded from their files. SS diagnosis was placed using the rating system according to 2016 ACREULAR classification criteria or based on expert opinion. Results: 113 patients met the ınclusion criteria. 72 patients diagnosed with SS. 56 were diagnosed according to the 2016 ACREULAR classification criteria and 16 were diagnosed according to expert opinion. There were 57 patients with positive MSGB outcomes 55 SS, 2 not SS. There were 56 patients with MSGB negative outcomes 17 SS, 39 not SS. The sensitivity of MSGB for SS diagnosis was 76.4, and the specificity was 95.1. Conclusion: All of our patients had antibody test results, but the number of objective tests included in the classification criteria such as salivary flow rate and Schirmer was low. Although MSGB is considered an invasive technique, it appears to be safe technique as long as it is performed by experienced professionals. It will assist in the final decision for patients with SS suspicion and who cannot undergo other objective tests.

 Objective: To evaluate the value and accuracy of biopsy in diagnosing Sjogren syndrome SS by evaluating the results of patients who underwent mınor salivary gland biopsy MSGB with the suspicion of SS. Material and Methods: The study was planned with a retrospective assessment of 127 patients with a biopsy performed for SS diagnosis. The clinical and laboratory characteristics of the patients who underwent MSGB were recorded from their files. SS diagnosis was placed using the rating system according to 2016 ACREULAR classification criteria or based on expert opinion. Results: 113 patients met the ınclusion criteria. 72 patients diagnosed with SS. 56 were diagnosed according to the 2016 ACREULAR classification criteria and 16 were diagnosed according to expert opinion. There were 57 patients with positive MSGB outcomes 55 SS, 2 not SS. There were 56 patients with MSGB negative outcomes 17 SS, 39 not SS. The sensitivity of MSGB for SS diagnosis was 76.4, and the specificity was 95.1. Conclusion: All of our patients had antibody test results, but the number of objective tests included in the classification criteria such as salivary flow rate and Schirmer was low. Although MSGB is considered an invasive technique, it appears to be safe technique as long as it is performed by experienced professionals. It will assist in the final decision for patients with SS suspicion and who cannot undergo other objective tests.

 Objective: To evaluate the value and accuracy of biopsy in diagnosing Sjogren syndrome SS by evaluating the results of patients who underwent mınor salivary gland biopsy MSGB with the suspicion of SS. Material and Methods: The study was planned with a retrospective assessment of 127 patients with a biopsy performed for SS diagnosis. The clinical and laboratory characteristics of the patients who underwent MSGB were recorded from their files. SS diagnosis was placed using the rating system according to 2016 ACREULAR classification criteria or based on expert opinion. Results: 113 patients met the ınclusion criteria. 72 patients diagnosed with SS. 56 were diagnosed according to the 2016 ACREULAR classification criteria and 16 were diagnosed according to expert opinion. There were 57 patients with positive MSGB outcomes 55 SS, 2 not SS. There were 56 patients with MSGB negative outcomes 17 SS, 39 not SS. The sensitivity of MSGB for SS diagnosis was 76.4, and the specificity was 95.1. Conclusion: All of our patients had antibody test results, but the number of objective tests included in the classification criteria such as salivary flow rate and Schirmer was low. Although MSGB is considered an invasive technique, it appears to be safe technique as long as it is performed by experienced professionals. It will assist in the final decision for patients with SS suspicion and who cannot undergo other objective tests.

 Amaç: Sjogren sendromu şüphesi ile minör tükürük bezi biyopsisi yapılan hastaların sonuçlarının değerlendirilerek biyopsinin Sjögren sendromu SS tanısındaki yerini ve değerini saptamak. Gereç ve Yöntemler: Çalışma, SS tanısı için biyopsi yapılan 127 hastanın sonuçlarının geriye dönük değerlendirilmesi ile planlandı. Minör tükürük bezi biyopsisi uygulanan hastaların klinik ve laboratuvar özellikleri dosyalarından kaydedildi. SS teşhisi, 2016 ACREULAR sınıflandırma kriterlerine göre veya uzman görüşüne göre konuldu. Bulgular: 113 hasta çalışmaya dahil edilme kriterlerini karşıladı. Sjogren sendromu tanısı konulan 72 hasta vardı. 72 hastanın 56 tanesine 2016 ACREULAR sınıflandırma kriterlerine göre tanı konulurken, 16 tanesine uzman görüşüne göre tanı konuldu. Minör tükürük bezi biyopsi sonucu pozitif 57 55 SS, 2SS değil, negatif 56 17SS, 39SS değil kişi vardı. Minör tükürük bezi biyopsisinin SS tanısı için duyarlılığı 76,4, özgüllüğü ise 95,1 idi. Sonuç: Hastalarımızın tamamında antikor testi sonucu vardı ancak tükürük akış hızı ve Schirmer gibi sınıflandırma kriterlerinde yer alan objektif testi olan hasta sayısı düşüktü. Minör tükürük bezi biyopsisi invaziv bir teknik olarak görülse de deneyimli profesyoneller tarafından yapıldığı sürece güvenli bir teknik gibi görünmektedir. SS şüphesi olan ve diğer objektif testlerin uygulanmadığı hastalarda kesin karara varılmasında yardımcı olacaktır.

Makale detayları

Clinical characteristics and results of patients who underwent minor salivary gland biopsy with the suspicion of Sjogren syndrome

Yazarlar:

Öznur Kutluk | Fatih Çay

Yayıncı:

Balıkesir University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Balıkesir Medical Journal Vol.8 Issue 3, pp.129-137

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001336820

pISSN:

2564-6664

sjogren syndrome

diagnosis

minor salivary biopsysjogren sendromu,

tanı,

minör tükürük bezi biyopsisi

Sayı

Makale detayları

Clinical characteristics and results of patients who underwent minor salivary gland biopsy with the suspicion of Sjogren syndrome

Yazarlar: Öznur Kutluk | Fatih Çay

Yayıncı: Balıkesir University

Ana Başlıklar: Romatoloji ve Artrit

Dergi: Balıkesir Medical Journal Vol.8 Issue 3, pp.129-137

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001336820

pISSN: 2564-6664

sjogren syndrome

diagnosis

minor salivary biopsysjogren sendromu,

tanı,

minör tükürük bezi biyopsisi

Sayı

Yazarlar:

Öznur Kutluk | Fatih Çay

Yayıncı:

Balıkesir University

Ana Başlıklar:

Romatoloji ve Artrit

Dergi:

Balıkesir Medical Journal Vol.8 Issue 3, pp.129-137

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001336820

pISSN:

2564-6664