The Efficacy of Decreased Ovarian Reserve on in Vitro Fertilization Outcome

Özlem Kara; İdil Duran

Makale detayları

The Efficacy of Decreased Ovarian Reserve on in Vitro Fertilization Outcome

Yazarlar:

Özlem Kara | İdil Duran

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.315-318

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300286

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: In this study, we aimed to compare the effects of microdose and antagonist regimens on IVF-ICSI outcome. Materials and Methods: The study was conducted at the Maltepe University Medical Faculty Training and Research Hospital IVF Clinic during the period of 2018 and 2022. The files of the patients were reviewed retrospectively and age, duration of infertility, basal FSH level, body mass index, antral follicle number AFC, antimullerian hormon AMH level, retrieved oocyte number, metaphase 2 oocyte number, fertilization and pregnancy rates were evaluated. The patients in Group 1 n124 were treated by using gonadotropin releasing hormone GnRH microdose protocol and in Group 2 n136 were treated by using antagonist protocol. Results: There was no significant difference between the groups in terms of the characteristics of the patients such as age, infertility duration, basal FSH level body mass index, AFC and AMH level p0.05. The retrieved oocyte number, metaphase 2 oocyte number, fertilization rates and pregnancy rates were also similar p0.05. Conclusion: Our results demonstrated that microdose and antagonist regimens have similar effect in poor reponder women on IVF-ICSI outcome.

 Purpose: In this study, we aimed to compare the effects of microdose and antagonist regimens on IVF-ICSI outcome. Materials and Methods: The study was conducted at the Maltepe University Medical Faculty Training and Research Hospital IVF Clinic during the period of 2018 and 2022. The files of the patients were reviewed retrospectively and age, duration of infertility, basal FSH level, body mass index, antral follicle number AFC, antimullerian hormon AMH level, retrieved oocyte number, metaphase 2 oocyte number, fertilization and pregnancy rates were evaluated. The patients in Group 1 n124 were treated by using gonadotropin releasing hormone GnRH microdose protocol and in Group 2 n136 were treated by using antagonist protocol. Results: There was no significant difference between the groups in terms of the characteristics of the patients such as age, infertility duration, basal FSH level body mass index, AFC and AMH level p0.05. The retrieved oocyte number, metaphase 2 oocyte number, fertilization rates and pregnancy rates were also similar p0.05. Conclusion: Our results demonstrated that microdose and antagonist regimens have similar effect in poor reponder women on IVF-ICSI outcome.

 Purpose: In this study, we aimed to compare the effects of microdose and antagonist regimens on IVF-ICSI outcome. Materials and Methods: The study was conducted at the Maltepe University Medical Faculty Training and Research Hospital IVF Clinic during the period of 2018 and 2022. The files of the patients were reviewed retrospectively and age, duration of infertility, basal FSH level, body mass index, antral follicle number AFC, antimullerian hormon AMH level, retrieved oocyte number, metaphase 2 oocyte number, fertilization and pregnancy rates were evaluated. The patients in Group 1 n124 were treated by using gonadotropin releasing hormone GnRH microdose protocol and in Group 2 n136 were treated by using antagonist protocol. Results: There was no significant difference between the groups in terms of the characteristics of the patients such as age, infertility duration, basal FSH level body mass index, AFC and AMH level p0.05. The retrieved oocyte number, metaphase 2 oocyte number, fertilization rates and pregnancy rates were also similar p0.05. Conclusion: Our results demonstrated that microdose and antagonist regimens have similar effect in poor reponder women on IVF-ICSI outcome.

 Amaç: Biz bu çalışmada mikrodoz ve antagonist rejimlerin IVF-ICSI sonucu üzerindeki etkilerini karşılaştırmayı amaçladık. Araçlar ve Yöntem: Çalışma 2018-2022 yılları arasında Maltepe Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi Tüp Bebek Kliniğinde gerçekleştirildi. Hastaların dosyaları retrospektif olarak incelendi ve yaş, infertilite süresi, bazal FSH düzeyi, vücut kitle indeksi, antral folikül sayısı AFC, antimüllerian hormon AMH düzeyi, toplanan oosit sayısı, metafaz 2 oosit sayısı, fertilizasyon ve gebelik oranları değerlendirildi. Grup 1deki hastalara n124 gonadotropin releasing hormon GnRH mikrodoz protokolü, Grup 2deki n136 hastalara ise antagonist protokol uygulandı. Bulgular: Hastaların yaş, infertilite süresi, bazal FSH düzeyi vücut kitle indeksi, AFC ve AMH düzeyi gibi parametreler açısından gruplar arasında anlamlı fark yoktu p0.05. Elde edilen oosit sayısı, metafaz 2 oosit sayısı, fertilizasyon oranları ve gebelik oranları da benzerdi p0.05. Sonuç: Bizim sonuçlarımız, mikrodoz ve antagonist rejimlerin zayıf yanıt veren kadınlarda IVF-ICSI sonucu üzerinde benzer etkiye sahip olduğunu göstermiştir.

Makale detayları

The Efficacy of Decreased Ovarian Reserve on in Vitro Fertilization Outcome

Yazarlar:

Özlem Kara | İdil Duran

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.315-318

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300286

pISSN:

2619-9203

antagonist regimen

ın vitro fertilization

microdose protocol

poor responder

pregnancyIn vitro fertilizasyon

zayıf yanıt veren

gebelik

mikrodoz protokol

antagonist rejim

Sayı

Makale detayları

Yazarlar: Özlem Kara | İdil Duran

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.315-318

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001300286

pISSN: 2619-9203

Sayı

Yazarlar:

Özlem Kara | İdil Duran

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.315-318

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001300286

pISSN:

2619-9203