In Vitro Antibacterial Effect of Hesperidin Microemulsion to Staphylococcus aureus and Listeria monocytogenes

Harun Hızlısoy

Makale detayları

In Vitro Antibacterial Effect of Hesperidin Microemulsion to Staphylococcus aureus and Listeria monocytogenes

Yazarlar:

Harun Hızlısoy

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Gıda Hijyeni ve Teknolojisi

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 2, pp.117-121

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314967

pISSN:

1308-1594

Anahtar kelimeler:

Özet:

 Foodborne bacterial infections and intoxications constitute a large proportion of bacterial diseases worldwide. In recent years, there has been an increasing resistance to chemotherapeutics used in the treatment of these diseases. Studies have shown that some compounds extracted from natural products and plants have alternative potential to antibiotics. In this study, it was aimed to reveal the antimicrobial potential of hesperidin microemulsion on Listeria monocytogenes and Staphylococcus aureus. In the study, the broth microdilution method was used to demonstrate in vitro antimicrobial activity. In the microdilution test, the MIC values of hesperidin for S. aureus and L. monocytogenes were as 128 μgmL. In comparison, the MIC values of ampicillin for S. aureus and L. monocytogenes were as 0.5 μgmL. Hesperidin is a compound with biologically valuable properties. Its antimicrobial effect may open a promising field as an alternative to antibiotics. However, detailed studies on hesperidin and similar potential active substances are needed to fully understand its therapeutic potential and to define its mechanisms of action.

 Foodborne bacterial infections and intoxications constitute a large proportion of bacterial diseases worldwide. In recent years, there has been an increasing resistance to chemotherapeutics used in the treatment of these diseases. Studies have shown that some compounds extracted from natural products and plants have alternative potential to antibiotics. In this study, it was aimed to reveal the antimicrobial potential of hesperidin microemulsion on Listeria monocytogenes and Staphylococcus aureus. In the study, the broth microdilution method was used to demonstrate in vitro antimicrobial activity. In the microdilution test, the MIC values of hesperidin for S. aureus and L. monocytogenes were as 128 μgmL. In comparison, the MIC values of ampicillin for S. aureus and L. monocytogenes were as 0.5 μgmL. Hesperidin is a compound with biologically valuable properties. Its antimicrobial effect may open a promising field as an alternative to antibiotics. However, detailed studies on hesperidin and similar potential active substances are needed to fully understand its therapeutic potential and to define its mechanisms of action.

 Foodborne bacterial infections and intoxications constitute a large proportion of bacterial diseases worldwide. In recent years, there has been an increasing resistance to chemotherapeutics used in the treatment of these diseases. Studies have shown that some compounds extracted from natural products and plants have alternative potential to antibiotics. In this study, it was aimed to reveal the antimicrobial potential of hesperidin microemulsion on Listeria monocytogenes and Staphylococcus aureus. In the study, the broth microdilution method was used to demonstrate in vitro antimicrobial activity. In the microdilution test, the MIC values of hesperidin for S. aureus and L. monocytogenes were as 128 μgmL. In comparison, the MIC values of ampicillin for S. aureus and L. monocytogenes were as 0.5 μgmL. Hesperidin is a compound with biologically valuable properties. Its antimicrobial effect may open a promising field as an alternative to antibiotics. However, detailed studies on hesperidin and similar potential active substances are needed to fully understand its therapeutic potential and to define its mechanisms of action.

 Gıda kaynaklı bakteriyel enfeksiyonlar ve zehirlenmeler dünya genelinde bakteriyel hastalıkların büyük bir bölümünü oluşturmaktadır. Son yıllarda bu hastalıkların tedavisinde kullanılan kemoterapötiklere karşı artan bir direnç söz konusudur. Yapılan çalışmalar, doğal ürünlerden ve bitkilerden elde edilen bazı bileşiklerin antibiyotiklere alternatif potansiyele sahip olduğunu göstermiştir. Bu çalışmada hesperidin mikroemülsiyonunun Listeria monocytogenes ve Staphylococcus aureus üzerindeki antimikrobiyal potansiyelinin ortaya konulması amaçlanmıştır. Çalışmada, in vitro antimikrobiyal aktiviteyi göstermek için broth mikrodilüsyon yöntemi kullanılmıştır. Mikrodilüsyon testinde hesperidinin S. aureus ve L. monocytogenes için MİK değerleri 128 μgmL olarak bulunmuştur. Buna karşılık, ampisilinin S. aureus ve L. monocytogenes için MİK değerleri 0.5 μgmL olarak bulunmuştur. Hesperidin biyolojik olarak değerli özelliklere sahip bir bileşiktir. Antimikrobiyal etkisi antibiyotiklere alternatif olarak umut verici bir alan açabilir. Bununla birlikte, terapötik potansiyelini tam olarak anlamak ve etki mekanizmalarını tanımlamak için hesperidin ve benzeri potansiyel aktif maddeler üzerinde ayrıntılı çalışmalara ihtiyaç vardır.

Makale detayları

In Vitro Antibacterial Effect of Hesperidin Microemulsion to Staphylococcus aureus and Listeria monocytogenes

Yazarlar:

Harun Hızlısoy

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Gıda Hijyeni ve Teknolojisi

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 2, pp.117-121

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314967

pISSN:

1308-1594

Antibacterial

Staphylococcus aureus

Listeria monocytogenes

MIC

HesperidinHesperidin

Antibakteriyel

Staphylococcus aureus

Listeria monocytogenes

MIC

Sayı

Makale detayları

Yazarlar: Harun Hızlısoy

Yayıncı: Afyon Kocatepe University

Ana Başlıklar: Veteriner Gıda Hijyeni ve Teknolojisi

Dergi: Kocatepe Veteriner Dergisi Vol.17 Issue 2, pp.117-121

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001314967

pISSN: 1308-1594

Sayı

Yazarlar:

Harun Hızlısoy

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Gıda Hijyeni ve Teknolojisi

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 2, pp.117-121

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314967

pISSN:

1308-1594